CD117-Targeted Intraoperative Imaging of Gastrointestinal Stromal Tumor Using a Stem-Cell-Factor-Labeled Fluorophore [0.03%]
基于干细胞因子标记的荧光内镜成像技术在胃肠道间质瘤术中的应用研究
Shinsuke Nomura,Shinya Yokomizo,Zhidong Wang et al.
Shinsuke Nomura et al.
Complete resection without damaging the capsule is the gold-standard surgical approach for nonmetastatic gastrointestinal stromal tumors (GIST). However, accurately locating tumors during surgery is challenging because GIST is covered by no...
Long-Term Neural Recording Performance of PEDOT/CNT/Dexamethasone Coated Electrode Array Implanted in Visual Cortex of Rats [0.03%]
PEDOT/CNT/地塞米松涂覆电极阵列在大鼠视觉皮层的长期神经记录性能
Asiyeh Golabchi,Bingchen Wu,Zhanhong Jeff Du et al.
Asiyeh Golabchi et al.
Implantable neural electrode arrays can be inserted in the brain to provide single-cell electrophysiology recording for neuroscience research and brain-machine interface applications. However, maintaining signal quality over time is complic...
Long-Circulating Nanobody Confers Durable Prophylaxis against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Infection [0.03%]
长效循环纳米抗体对新型冠状病毒奥密克戎感染具有持久的预防作用
Geetha Jyothi Vaskuri,Gang Ye,Fan Bu et al.
Geetha Jyothi Vaskuri et al.
Breakthrough infections in vaccinated population and continuous emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants make it imperative to develop more efficacious medical countermeasures. Previously, an anti-S...
Evaluation of a Targeted Drug-Eluting Intravascular Nanotherapy to Prevent Neointimal Hyperplasia in an Atherosclerotic Rat Model [0.03%]
评估针对动脉粥样硬化 rat 模型内皮纳米治疗预防血管平滑肌细胞异位增生的效果
Emily R Newton,David C Gillis,Kui Sun et al.
Emily R Newton et al.
Objective: To test the hypothesis that nitric oxide-bearing collagen-targeted nanofibers will target vascular injury and inhibit neointimal hyperplasia in an atherosclerotic rat model. ...
Polymer design of microwell hydrogels influences epithelial-mesenchymal interactions during human bronchosphere formation [0.03%]
微波井水凝胶的聚合物设计可影响人支气管球形成的上皮-间质相互作用
Madeline K Eiken,Justin E Levine,Shinyeong Lee et al.
Madeline K Eiken et al.
Bronchospheres have emerged as a promising in vitro model towards probing questions on organ development and disease. Several organoid models, including from airway (e.g., bronchial, tracheal) cells, require 3D Matrigel, a complex mouse tum...
A Microfluidic Strategy to Capture Antigen-Specific High-Affinity B Cells [0.03%]
一种捕获抗原特异性高亲和力B细胞的微流控策略
Ahmed M Alhassan,Venktesh S Shirure,Jean Luo et al.
Ahmed M Alhassan et al.
Assessing B cell affinity to pathogen-specific antigens prior to or following exposure could facilitate the assessment of immune status. Current standard tools to assess antigen-specific B cell responses focus on equilibrium binding of the ...
Biodegradable Oxygen-Generating Microneedle Patches for Regenerative Medicine Applications [0.03%]
用于再生医学的可降解产氧微针贴片
Lindsay Barnum,Mohamadmahdi Samandari,Yasir Suhail et al.
Lindsay Barnum et al.
Upon injury, regenerating skin is metabolically active and requires oxygen for physiological processes related to wound healing. Such processes can be halted in hypoxic conditions common in chronic wounds. Microneedle arrays (MNAs) have bee...
Laponite nanoclay loaded microgel suspensions as supportive matrices for osteogenesis [0.03%]
负载Laponite纳米粘土的微凝胶悬浮液作为骨生成的支持性基质
Gagan K Jalandhra,Tzong-Tyng Hung,Kristopher A Kilian
Gagan K Jalandhra
Microscale carriers have emerged as promising materials for nurturing cell growth and as delivery vehicles for regenerative therapies. Carriers based on hydrogels have proved advantageous, where "microgels" can be formulated to have a broad...
Detection of Estrogen Receptor Status in Breast Cancer Cytology Samples by an Optical Nanosensor [0.03%]
光学纳米传感器在乳腺癌细胞学样本中检测雌激素受体状态
Pooja V Gaikwad,Nazifa Rahman,Pratyusha Ghosh et al.
Pooja V Gaikwad et al.
Breast cancer is a substantial source of morbidity and mortality worldwide. Estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2), are the primary biomarkers which inform breast cancer treatm...
Hyaluronic Acid Influences Amino Acid Metabolism via Differential L-Type Amino Acid Transporter 1 Expression in the U87-Malignant Glioma Cell Line [0.03%]
透明酸通过调节U87恶性胶质瘤细胞系中的L-型氨基酸转运蛋白1的表达影响氨基酸代谢
Ashwin A Bale,Swaroop Thammineni,Rohit Bhargava et al.
Ashwin A Bale et al.
The Glioblastoma (GBM) tumor microenvironment is heterogeneous, complex, and is being increasingly understood as a significant contributor to tumor progression. In brain tumors, the extracellular matrix contains a large concentration of Hya...