Physicochemical Descriptors in Biodistribution and Clearance of Contrast Agents [0.03%]
对比剂的物理化学表征在对比剂分布和清除过程中的作用
Sung Ahn,Benjamin Sanchez-Langeling,Jeong Heon Lee et al.
Sung Ahn et al.
Hepatobiliary and renal excretions are the two major in vivo elimination pathways, of which prediction is particularly important for the optimization of systemic and/or target-site exposure of new near-infrared (NIR) fluorescent contrast ag...
Evan M Mettenbrink,Wen Yang,Stefan Wilhelm
Evan M Mettenbrink
Bioimaging enables the spatiotemporal visualization of biological processes at various scales empowered by a range of different imaging modalities and contrast agents. Upconversion nanoparticles (UCNPs) represent a distinct type of such con...
Optical Tissue Phantoms for Quantitative Evaluation of Surgical Imaging Devices [0.03%]
用于定量评估外科成像设备的光学组织仿真体
Jason Dinh,Atsushi Yamashita,Homan Kang et al.
Jason Dinh et al.
Optical tissue phantoms (OTPs) have been extensively applied to the evaluation of imaging systems and surgical training. Due to their human tissue-mimicking characteristics, OTPs can provide accurate optical feedback on the performance of i...
In Vivo Assessment and Monitoring of Burn Wounds Using a Handheld Terahertz Hyperspectral Scanner [0.03%]
利用便携式太赫兹高光谱扫描仪对烧伤创面进行活体评估和监测
Omar B Osman,Zachery B Harris,Juin W Zhou et al.
Omar B Osman et al.
The accuracy of clinical assessment techniques in diagnosing partial-thickness burn injuries has remained as low as 50-76%. Depending on the burn depth and environmental factors in the wound, such as reactive oxygen species, inflammation, a...
Yuzhi Shi,Zhenyu Li,Patricia Yang Liu et al.
Yuzhi Shi et al.
The current outbreak of the coronavirus disease-19 (COVID-19) pandemic worldwide has caused millions of fatalities and imposed a severe impact on our daily lives. Thus, the global healthcare system urgently calls for rapid, affordable, and ...
Sub-10-nm distance measurements between fluorophores using photon-accumulation enhanced reconstruction (PACER) [0.03%]
利用光子累积增强重构(PACER)技术实现荧光分子间小于10纳米的距离测量
Biqin Dong,Ki-Hee Song,Janel L Davis et al.
Biqin Dong et al.
Single-molecule localization microscopy (SMLM) precisely localizes individual fluorescent molecules within the wide field of view. However, the localization precision is fundamentally limited to around 20 nm due to the physical photon limit...