Ingmar Blümcke
Ingmar Blümcke
Neuropathology-based studies in neurosurgically resected brain tissue obtained from carefully examined patients with focal epilepsies remain a treasure box for excellent insights into human neuroscience, including avenues to better understa...
Heterogeneity of DNA methylation profiles and copy number alterations in 10782 adult-type glioblastomas, IDH-wildtype [0.03%]
10782例成人型胶质母细胞瘤DNA甲基化谱及IDH野生型拷贝数改变的异质性分析
David E Reuss,Daniel Schrimpf,Asan Cherkezov et al.
David E Reuss et al.
The morphological patterns leading to the diagnosis of glioblastoma may also commonly be observed in several other distinct tumor entities, which can result in a mixed bag of tumors subsumed under this diagnosis. The 2021 WHO Classification...
Searching for a cut-off point for p53 immunohistochemistry as evidence of TP53 mutations [0.03%]
寻找p53免疫组化作为TP53突变证据的临界值
Ilay Caliskan,Rufei Lu,Cristine Szu Lyn Ding et al.
Ilay Caliskan et al.
HIV and COVID-19: two pandemics with significant (but different) central nervous system complications [0.03%]
HIV和COVID-19：两种具有显著（但不同）中枢神经系统并发症的传染病
Shino Magaki,Ting Zhang,Karam Han et al.
Shino Magaki et al.
Human immunodeficiency virus (HIV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cause significant neurologic disease. Central nervous system (CNS) involvement of HIV has been extensively studied, with well-documented inv...
Blocking TGF-β- and Epithelial-to-Mesenchymal Transition (EMT)-mediated activation of vessel-associated mural cells in glioblastoma impacts tumor angiogenesis [0.03%]
阻断胶质母细胞瘤中TGF-β和上皮间充质转化(EMT)介导的血管相关壁细胞活化影响肿瘤血管生成
Luisa Merk,Katja Regel,Hermann Eckhardt et al.
Luisa Merk et al.
Glioblastoma (GBM) is the most common malignant primary brain tumor in adults. GBM displays excessive and unfunctional vascularization which may, among others, be a reason for its devastating prognosis. Pericytes have been identified as the...
Cellular activation patterns of CD10+ fibro-adipogenic progenitors across acquired disease states in human skeletal muscle biopsies [0.03%]
人类骨骼肌活检中获得性疾病的CD10+成纤维脂肪祖细胞的激活模式
Peter W Schutz,Simon Cheung,Lin Yi et al.
Peter W Schutz et al.
Background: Fibro-adipogenic progenitors (FAP) are muscle resident mesenchymal stem cells pivotal for regulation of myofiber repair. Experimental results show in addition involvement in a range of other pathological conditions and potential...
William Charles McDonald
William Charles McDonald
The World Health Organization classification of pituitary tumors provides a framework for pathologists and researchers to classify pituitary adenomas. From the perspective of a practicing pathologist, this classification can be improved by ...
Deep RNA sequencing of muscle tissue reveals absence of viral signatures in dermatomyositis [0.03%]
肌肉组织的深度RNA序列分析显示皮肌炎中缺乏病毒特征
Victor M Corman,Corinna Preusse,Julia Melchert et al.
Victor M Corman et al.
Objective: To explore a possible connection between active viral infections and manifestation of dermatomyositis (DM). Methods: Skeletal muscle biopsies were analyzed from patients diagnosed with juvenile (n=10) and adult (n=12) DM. Adult D...
Considering the myelin-centric hypothesis: insights from Budka's historical adrenomyeloneuropathy case report [0.03%]
考虑髓鞘为中心的假说：从Budka的历史副神经节瘤病例报告中获得的启示
Ettore Salsano,Chiara Benzoni
Ettore Salsano