YAP1 fusion-positive ependymoma presenting in an adult with a pigmented phenotype and association with superficial siderosis [0.03%]
YAP1融合阳性室管膜瘤在成人中的表现及其与色素表型和浅表铁沉积症的关系
Osorio Lopes Abath Neto,Leonardo Furtado Freitas,Martha Quezado et al.
Osorio Lopes Abath Neto et al.
Striking intraneuronal neurofilament inclusions restricted to the locus coeruleus in a patient with Creutzfeldt-Jakob disease [0.03%]
一名克雅氏病(Creutzfeldt-Jakob disease)患者的黑质蓝斑核神经纤维缠结现象
Felix Leitner,Sigrid Klotz,Karoline Ornig et al.
Felix Leitner et al.
Michel Mittelbronn
Michel Mittelbronn
As in previous years, including 2023, a major focus in the neurooncological area of neuropathology was put on more precise and constantly faster diagnostic procedures, even reaching the level of ultra-fast intraoperative diagnostics based o...
María Martínez de Lagrán,Karen Bascón-Cardozo,Mara Dierssen
María Martínez de Lagrán
Neurodevelopmental disorders encompass a range of conditions such as intellectual disability, autism spectrum disorder, rare genetic disorders and developmental and epileptic encephalopathies, all manifesting during childhood. Over 1,500 ge...
68th Annual Meeting of the German Society of Neuropathology and Neuroanatomy (DGNN) - Meeting Abstracts: September 12-14, 2024, Regensburg, Germany [0.03%]
2024年9月12-14日德国神经病理学和神经解剖学协会第68届年度会议摘要：德国雷根斯堡
Dear colleagues, It is my pleasure and honor to host the 68th Annual Meeting of the German Society of Neuropathology and Neuroanatomy (DGNN) in Regensburg. Since the Magdeburg meeting in 2019 this is the first pure national meeting of our s...
Mesial temporal lobe epilepsy and hippocampal sclerosis associated with BRAFV600E mutant neurons in the Cornu Ammonis: an uncertain pathogenesis and a diagnostic challenge [0.03%]
BRAF V600E突变神经元与海马硬化相关的颞叶内侧癫痫：不确定的发病机制和诊断挑战
Samir Alsalek,Alexander S Himstead,Scott Self et al.
Samir Alsalek et al.
Mesial temporal lobe epilepsy (MTLE) is a common cause of seizures, and hippocampal sclerosis (HS) is the predominant subtype. BRAFV600E mutations in MTLE-HS have only been reported infrequently. Herein, we illustrate the neurologic, radiol...
Cell-in-cell phenomena of intracellular neutrophils in a recurrent pleomorphic xanthoastrocytoma [0.03%]
复发性多形黄色星形细胞瘤中的中性粒细胞胞内包涵现象
Gianna M Fote,Kamran Urgun,Jordan Davies et al.
Gianna M Fote et al.
We describe a case of a young patient with a recurrent pleomorphic xanthoastrocytoma (PXA) showing unusual cell-in-cell (CiC) phenomena. We observed mostly viable but also necrotic neutrophils engulfed within tumor cells. The recurrent tumo...
Benjamin Englert,Sigrun Roeber,Thomas Arzberger et al.
Benjamin Englert et al.
Background: The postmortem diagnostic of individuals having suffered presumptive neurodegenerative disease comprises exclusion of a prion disease, extensive brain sampling and histopathological evaluation, which are resource-intensive and t...
An optimized filter trap assay for detecting recombinant authentic tau fibrils [0.03%]
一种优化的滤过陷阱法用于检测重组天然tau淀粉样纤维
Allison R Balaj,Thomas L Rothstein,Hiroaki Kaku
Allison R Balaj
The development and optimization of the Filter Trap Assay (FTA) for the detection of authentic tau fibrils in vitro mark a pivotal advancement in the realm of tauopathy research, particularly by addressing the limitations of using polyanion...
Stem cell-associated transcription factors in non-functioning pituitary neuroendocrine tumours [0.03%]
与垂体神经内分泌肿瘤相关的干细胞转录因子
Kristin Astrid Øystese,Nicoleta Cristina Olarescu,Cecilia Lindskog et al.
Kristin Astrid Øystese et al.
Background: Cells with stem cell features have been described in pituitary neuroendocrine tumours (PitNETs). Transcription factors SOX2 and SOX9 are stem cell-associated markers while the pituitary progenitor marker PROP1 is involved in ant...