Alyona Ivanova,David G Munoz,John Woulfe
Alyona Ivanova
There is considerable evidence for a role for metabolic dysregulation, including disordered purine nucleotide metabolism, in the pathogenesis of Alzheimer's disease (AD). Purine nucleotide synthesis in the brain is regulated with high fidel...
Increased frontocortical microvascular raspberry density in frontotemporal lobar degeneration compared to Lewy body disease and control cases: a neuropathological study [0.03%]
额颞叶变性与路易体疾病和对照病例相比额皮质微血管树莓密度增加的神经病理学研究
Henric Ek Olofsson,Elisabet Englund
Henric Ek Olofsson
Background: Brain raspberries are histologically defined microvascular entities that are highly prevalent in the neocortex. Increased cortical raspberry density occurs in vascular dementia, but also with advancing age. Here, we examined the...
A novel KDM2A::YAP1 fusion in a pediatric supratentorial CNS neoplasm resembling a tumor with BCOR internal tandem duplication [0.03%]
儿童幕上CNS肿瘤中出现的一种新的KDM2A::YAP1融合，类似于具有BCOR内部串联重复的肿瘤
Arnault Tauziède-Espariat,Alice Métais,Dorian Bochaton et al.
Arnault Tauziède-Espariat et al.
Capillary basal lamina in human brain and spinal cord has fibrillar collagen type I and type III: Ignorance may not be bliss [0.03%]
人脑和脊髓的毛细血管基底膜含有I型和III型纤维状胶原蛋白：无知未必是福
Wen-Lang Lin,Dennis W Dickson
Wen-Lang Lin
The capillary basal lamina (BL) located between the endothelial cell, pericyte and perivascular astrocyte plays important roles in normal and diseased central nervous system (CNS). Using immunohistochemistry (IHC), electron microscopy (EM) ...
Parkinsonism associated with prolonged unresponsive wakefulness syndrome after blunt head injury: a clinico-pathological study [0.03%]
钝器伤后持续植物状态相关的帕金森综合征的临床病理研究
Kurt A Jellinger
Kurt A Jellinger
Objective: Survival after traumatic brain injury (TBI) and posttraumatic parkinsonian-like symptoms is increasing, in particular in those patients developing during disease course an unresponsive wakefulness syndrome (UWS) previously termed...
A novel FUS::BEND2 fusion expanding the molecular spectrum of astroblastomas [0.03%]
新颖的FUS::BEND2融合蛋白扩大了星形细胞母细胞瘤分子谱系的范围
Arnault Tauziède-Espariat,Benjamin Bonhomme,Nathalène Truffaux et al.
Arnault Tauziède-Espariat et al.
Andrew T McKenzie,Emma L Thorn,Oge Nnadi et al.
Andrew T McKenzie et al.
Cryopreservation, the preservation of tissues at subzero temperatures, is a mainstay of brain banking that allows for the storage of brain tissue without the use of chemical fixatives. This is particularly important for molecular studies th...
Adult glioblastoma with Lynch syndrome-associated mismatch repair deficiency forms a distinct high-risk molecular subgroup [0.03%]
成人胶质母细胞瘤伴林奇综合征相关错配修复缺陷形成一个独特的高危分子亚组
Maria-Magdalena Georgescu
Maria-Magdalena Georgescu
Glioblastoma is the most frequent and malignant primary brain tumor. Although the survival is generally dismal for glioblastoma patients, risk stratification and the identification of high-risk subgroups is important for prompt and aggressi...
John F Crary
John F Crary
This review highlights a collection of both diverse and highly impactful studies published in the previous year selected by the author from the neurodegenerative neuropathology literature. As with previous reviews in this series, the focus ...
Northern Lights Neuroscience Symposium 2024: Expanding Spectrum of Common Dementia Disorders [0.03%]
2024年北方神经科学研讨会：常见痴呆症谱系的扩展视野
The Northern Lights Neuroscience Symposium 2024 "Expanding Spectrum of Common Dementia Disorders" was held in Hanasaari, Helsinki (Espoo), Finland on September 26-27, 2024. The meeting was jointly organised by the Scandinavian Neuropatholog...