Applying machine learning to assist in the morphometric assessment of brain arteriolosclerosis through automation [0.03%]
利用机器学习进行脑小动脉硬化形态学评估的自动化研究
Jerry J Lou,Peter Chang,Kiana D Nava et al.
Jerry J Lou et al.
Objective quantification of brain arteriolosclerosis remains an area of ongoing refinement in neuropathology, with current methods primarily utilizing semi-quantitative scales completed through manual histological examination. These approac...
Selective cellular and regional vulnerability in frontotemporal lobar degeneration: a scoping review [0.03%]
选择性细胞和区域易感性在额颞叶变性中的作用：综述研究
Kashif Ravasia,Veronica Hirsch-Reinshagen
Kashif Ravasia
The three main types of frontotemporal lobar degeneration (FTLD) are characterized by the accumulation of abnormal proteins, namely tau, TDP-43 and FUS. The distribution of these proteins within different human brain regions is well known, ...
Michel Mittelbronn
Michel Mittelbronn
This collection of studies highlights groundbreaking advancements in brain tumor research, particularly primary CNS tumors and brain metastasis. One major focus is the tumor microenvironment, where alterations in cerebral microcirculation a...
Morphological substrate of chronic schizophrenia in elderly patients: a clinicopathological study [0.03%]
老年慢性精神分裂症患者的形态学基础：一项临床病理研究
Kurt A Jellinger
Kurt A Jellinger
Objective: Patients with schizophrenia are at a higher risk of developing dementia, but the basis of cognitive impairment is a matter of discussion. Conflicting results regarding the association of schizophrenia with Alzheimer disease (AD) ...
Alyona Ivanova,David G Munoz,John Woulfe
Alyona Ivanova
There is considerable evidence for a role for metabolic dysregulation, including disordered purine nucleotide metabolism, in the pathogenesis of Alzheimer's disease (AD). Purine nucleotide synthesis in the brain is regulated with high fidel...
Increased frontocortical microvascular raspberry density in frontotemporal lobar degeneration compared to Lewy body disease and control cases: a neuropathological study [0.03%]
额颞叶变性与路易体疾病和对照病例相比额皮质微血管树莓密度增加的神经病理学研究
Henric Ek Olofsson,Elisabet Englund
Henric Ek Olofsson
Background: Brain raspberries are histologically defined microvascular entities that are highly prevalent in the neocortex. Increased cortical raspberry density occurs in vascular dementia, but also with advancing age. Here, we examined the...
A novel KDM2A::YAP1 fusion in a pediatric supratentorial CNS neoplasm resembling a tumor with BCOR internal tandem duplication [0.03%]
儿童幕上CNS肿瘤中出现的一种新的KDM2A::YAP1融合，类似于具有BCOR内部串联重复的肿瘤
Arnault Tauziède-Espariat,Alice Métais,Dorian Bochaton et al.
Arnault Tauziède-Espariat et al.
Capillary basal lamina in human brain and spinal cord has fibrillar collagen type I and type III: Ignorance may not be bliss [0.03%]
人脑和脊髓的毛细血管基底膜含有I型和III型纤维状胶原蛋白：无知未必是福
Wen-Lang Lin,Dennis W Dickson
Wen-Lang Lin
The capillary basal lamina (BL) located between the endothelial cell, pericyte and perivascular astrocyte plays important roles in normal and diseased central nervous system (CNS). Using immunohistochemistry (IHC), electron microscopy (EM) ...
Parkinsonism associated with prolonged unresponsive wakefulness syndrome after blunt head injury: a clinico-pathological study [0.03%]
钝器伤后持续植物状态相关的帕金森综合征的临床病理研究
Kurt A Jellinger
Kurt A Jellinger
Objective: Survival after traumatic brain injury (TBI) and posttraumatic parkinsonian-like symptoms is increasing, in particular in those patients developing during disease course an unresponsive wakefulness syndrome (UWS) previously termed...
A novel FUS::BEND2 fusion expanding the molecular spectrum of astroblastomas [0.03%]
新颖的FUS::BEND2融合蛋白扩大了星形细胞母细胞瘤分子谱系的范围
Arnault Tauziède-Espariat,Benjamin Bonhomme,Nathalène Truffaux et al.
Arnault Tauziède-Espariat et al.