Detailed neuropathologic report of COVID-19 complicated by large intracerebral hemorrhage and periventricular lesions with macrophagic infiltrates [0.03%]
合并大面积脑出血和室周病变的新冠肺炎患者的神经病理报告
Adrian Levine,Carol Lee,Craig Fava et al.
Adrian Levine et al.
Infection with the SARS-CoV-2 virus affects a wide range of systems. Significant involvement of the central nervous system has been described, including ischemic and hemorrhagic strokes. Thus far, neuropathologic reports of patients who pas...
Neurotrauma: 2021 update [0.03%]
神经创伤：2021年更新
Daniel P Perl
Daniel P Perl
Despite the interruptions and restrictions to the progress of science that the COVID-19 pandemic has introduced, 2020 was marked by a number of important advances in the field of neurotrauma. Here, I will highlight what I believe are among ...
Marta Margeta
Marta Margeta
This review highlights ten important advances in the neuromuscular disease field that were first reported in 2020. The overarching topics include (i) advances in understanding of fundamental neuromuscular biology; (ii) new / emerging diseas...
Pieter Wesseling
Pieter Wesseling
This article briefly presents 10 topics that were selected by the author as 'top 10 discoveries' published in 2020 in the broader field of neurooncological pathology including neurosciences as well as clinical neurooncology of interest for ...
SARS-CoV-2 vaccination induced cerebral venous sinus thrombosis: Do megakaryocytes, platelets and lipid mediators make up the orchestra? [0.03%]
新冠疫苗引起的脑静脉窦血栓：巨核细胞、血小板和脂类介质是幕后推手吗？
Kate Chander Chiang,Ravi Raghavan,Ajay Gupta
Kate Chander Chiang
The COVID-19 vaccines comprised of adenoviral vectors encoding the Spike (S) glycoprotein of SARS-CoV-2 are highly effective but associated with rare thrombotic complications. The adenovirus vector infects epithelial cells expressing the co...
Andrew T McKenzie,Emma Woodoff-Leith,Diana Dangoor et al.
Andrew T McKenzie et al.
Perfusion fixation is a well-established technique in animal research to improve preservation quality in the study of many tissues, including the brain. There is a growing interest in using perfusion to fix postmortem human brain tissue to ...
Post-mortem neuropathologic examination of a 6-case series of CAR T-cell treated patients [0.03%]
供CAR-T细胞治疗的6名患者的死后神经病理学检查结果分析
Nuria Vidal-Robau,Gabriela Caballero,Ivan Archilla et al.
Nuria Vidal-Robau et al.
Introduction: Chimeric antigen receptor (CAR) T-cell therapy is a promising immunotherapy for the treatment of refractory hematopoietic malignancies. Adverse events are common, and neurotoxicity is one of the most important. However, the ph...
Neuropathological findings in possible normal pressure hydro-cephalus: A post-mortem study of 29 cases with lifelines [0.03%]
可能的正常压力脑积水患者的神经病理学发现：29例尸检研究及其生命线分布
Joni J Hänninen,Madoka Nakajima,Aleksi Vanninen et al.
Joni J Hänninen et al.
Aims: There are very few detailed post-mortem studies on idiopathic normal-pressure hydrocephalus (iNPH) and there is a lack of proper neuropathological criteria for iNPH. This study aims to update the knowledge on the neuropathology of iNP...
Miguel Sabariego-Navarro,Álvaro Fernández-Blanco,Cesar Sierra et al.
Miguel Sabariego-Navarro et al.
With a prevalence of 2-4% of the worldwide population, neurodevelopmental disorders (NDDs) comprise a heterogeneous group of disorders associated with neurodevelopmental dysfunction, including intellectual disability (ID), autism spectrum d...
Pigmented ependymoma, a tumor with predilection for the middle-aged adult: case report with methylation classification and review of 16 literature cases [0.03%]
色素性室管膜瘤是一种偏爱中年人的肿瘤：甲基化分类病例报告及16例文献复习
Alexander S Himstead,Mari Perez-Rosendahl,Gianna M Fote et al.
Alexander S Himstead et al.
Ependymomas have rarely been described to contain pigment other than melanin, neuromelanin, lipofuscin or a combination. In this case report, we present a pigmented ependymoma in the fourth ventricle of an adult patient and review 16 additi...