Jacqueline Mikol
Jacqueline Mikol
Clayton A Wiley
Clayton A Wiley
For the past 400 years, the most common cause of dementia was tertiary syphilis [1]. Its prevalence declined dramatically with the advent of potent antibiotics in the 20th century, but these same antibiotics also helped increase our average...
Fatma E El-Khouly,Rianne Haumann,Marjolein Breur et al.
Fatma E El-Khouly et al.
Aims: Diffuse intrinsic pontine glioma (DIPG) is a childhood brainstem tumor with a median overall survival of eleven months. Lack of chemotherapy efficacy may be related to an intact blood-brain barrier (BBB). In this study we aim to inves...
Arnulf H Koeppen,Rahman F Rafique,Joseph E Mazurkiewicz et al.
Arnulf H Koeppen et al.
Heart disease is an integral part of Friedreich ataxia (FA) and the most common cause of death in this autosomal recessive disease. The result of the mutation is lack of frataxin, a small mitochondrial protein. The clinical and pathological...
Molecular clarification of brainstem astroblastoma with EWSR1-BEND2 fusion in a 38-year-old man [0.03%]
成人脑干星形细胞瘤伴EWSR1-BEND2融合基因的分子病理学研究
Matthew A Smith-Cohn,Zied Abdullaev,Kenneth D Aldape et al.
Matthew A Smith-Cohn et al.
The majority of astroblastoma occur in a cerebral location in children and young adults. Here we describe the unusual case of a 38-year-old man found to have a rapidly growing cystic enhancing circumscribed brainstem tumor with high grade h...
John F Crary
John F Crary
This article reviews a collection of manuscripts in the field of neurodegenerative disease chosen from what are considered by the author to be among the 10 most important and potentially impactful topics or research trends of 2020 relevant ...
Desmoplastic myxoid tumor of pineal region, SMARCB1-mutant, in young adult [0.03%]
年轻成人松果体区黏液样肌成纤维细胞瘤伴SMARCB1基因突变
Branavan Manoranjan,Yves P Starreveld,Robert A Nordal et al.
Branavan Manoranjan et al.
We present a young adult woman who developed a myxoid tumor of the pineal region having a SMARCB1 mutation, which was phenotypically similar to the recently described desmoplastic myxoid, SMARCB1-mutant tumor of the pineal region (DMT-SMARC...
Taylor's focal cortical dysplasia revisited: History, original specimens and impact [0.03%]
重新审视特莱尔局灶性皮质发育不良：历史、原始标本及影响
Burkhard S Kasper
Burkhard S Kasper
50 years ago back in 1971, David C. Taylor and colleagues from England reported on a small series of surgical epilepsy cases proposing a new type of tissue lesion as a cause of difficult-to-treat focal epilepsy: a localized malformation of ...
Differentiation of primary CNS lymphoma and glioblastoma using Raman spectroscopy and machine learning algorithms [0.03%]
基于拉曼光谱和机器学习算法区分原发性中枢神经系统淋巴瘤和胶质母细胞瘤
Gilbert Georg Klamminger,Karoline Klein,Laurent Mombaerts et al.
Gilbert Georg Klamminger et al.
Objective and Methods: Timely discrimination between primary CNS lymphoma (PCNSL) and glioblastoma is crucial for diagnosis and therapy, but also determines the intraoperative surgical course. Advanced radiological methods allow for their d...