Deep Learning-Assisted Digital Microfluidic Platform for Automated CRISPR/Cas12 Detection of Mycobacterium tuberculosis [0.03%]
基于深度学习的数字微流控平台实现结核分支杆菌CRISPR/Cas12自动化检测技术
Indira Singh,Peeraphan Compiro,Pornchai Keawsapsak et al.
Indira Singh et al.
CRISPR-based diagnostics offer high sensitivity and specificity for nucleic acid detection, but their translation to point-of-care use remains limited by dependence on benchtop instrumentation, manual reagent handling, and costly optical co...
Linking Nanoscale Film Properties to Electrochemical Response in Cytochrome P450 Membrane Enzyme Films [0.03%]
细胞色素P450膜酶薄膜的纳米级性质与电化学响应之间的关系
Silan Bhandari,Matthew Dixon,Charuksha Walgama et al.
Silan Bhandari et al.
Membrane-bound human liver cytochrome P450 (CYP) enzymes catalyze key steps in xenobiotic metabolism, yet their integration into analytical devices depends critically on surface chemistry and film mechanics. Bacterial membrane preparations ...
High-throughput Optical Analysis to Inform Design of Electrochemical Biosensors [0.03%]
高通量光学分析在电化学生物传感器设计中的应用
Nathan J Ricks,Michael A Pence,Monica Brachi et al.
Nathan J Ricks et al.
Electrochemical biosensors are central to wearable diagnostics, point-of-care testing, and continuous health monitoring due to their low power requirements, compatibility with miniaturized electronics, and proven clinical impact. Despite th...
Peptide-Functionalized Silicon-Photonic E‑Nose for Monitoring Oxidation in Extra Virgin Olive Oil [0.03%]
具有肽官能团的硅基光子E型嗅觉传感器监测特级初榨橄榄油的氧化程度
Hamed Karami,Antonio Pardo,Luis Fernández et al.
Hamed Karami et al.
Oxidation is a major factor affecting the quality and shelf life of Extra Virgin Olive Oil (EVOO), leading to chemical degradation and loss of freshness. This study investigates the assessment of EVOO freshness using a peptide-based optoele...
Chemotaxonomic and Molecular Insights into Phytoplankton Communities in Tropical Aquatic Ecosystems via MALDI FT-ICR Mass Spectrometry [0.03%]
基于MALDI FT-ICR质谱技术的热带水生生态系统浮游植物群落的化学分类学及分子机制研究
Luis M Díaz-Sánchez,Martha L Aguilera,David Stranz et al.
Luis M Díaz-Sánchez et al.
Accurate identification of phytoplankton communities is essential for understanding the ecological dynamics of aquatic ecosystems. Conventional optical microscopy, while widely used, is labor-intensive and limited in its ability to resolve ...
Epitope-Imprinted Polymers for Selective Recognition of Bacterial Proteins: From Design to Analytical Applications [0.03%]
从设计到分析应用的细菌蛋白识别位点印迹聚合物研究进展
Ahmed S El-Tahlawy,Mohamed Aly Saad Aly,Stefano Cinti et al.
Ahmed S El-Tahlawy et al.
Epitope-imprinted polymers (EIPs) represent an advanced evolution of molecular imprinting technology for selective bacterial recognition. By using short, surface-exposed peptide fragments derived from bacterial proteins rather than whole ce...
Voltammetric Translation with Transformers: Converting Cyclic Voltammograms to Differential Pulse Voltammograms [0.03%]
基于变压器的伏安图转换：将循环伏安图转换为差分脉冲伏安图
Byoung-Yong Chang
Byoung-Yong Chang
Here we report a voltammogram translation framework that converts cyclic voltammograms into differential pulse voltammograms, enabling protocol interoperability without requiring paired experimental corpora. We formulate CV → DPV conversio...
Optical, Chemical, and Biological Detection Methods of Microplastics and Nanoplastics [0.03%]
微塑料和纳米塑料的光学、化学和生物检测方法
Carlos Vico,Song Lin Chua
Carlos Vico
Microplastics and nanoplastics (MNPs) are pervasive environmental contaminants with major impacts on ecosystems and human health. This raises the need to accurately detect and characterize MNPs to understand their sources, transport, fate, ...
Graphical Visualization Approach for Two-Dimensional Liquid Chromatography with Parallel Column Arrays [0.03%]
二维液相色谱并行柱阵列图形化可视化方法研究
Deklin Parker,Samuel W Foster,Tina Dahlseid et al.
Deklin Parker et al.
Two-dimensional liquid chromatography (2D-LC) is one of the highest-resolution techniques available to chromatographers for the separation of analytes in complex mixtures. However, data analysis and data visualization remain challenging, es...
Conrad B Milton,Mahmuda Akter,Olivia M Kawakita et al.
Conrad B Milton et al.
Glioblastoma, as the most common malignant brain tumor in humans, remains a big societal challenge; identifying new signaling molecules in glioblastoma opens avenues for alternative treatment strategies. Emerging evidence suggests that neur...