Improved Microplastic Identification from Simultaneously Collected Photothermal Infrared and Raman Spectra Using Multiview Conformal Prediction [0.03%]
基于多视图符合预测的微塑料光热红外和拉曼联合检测方法研究
Rebecca L Parham,Eduardo Ochoa Rivera,Abbygail M Ayala et al.
Rebecca L Parham et al.
Microplastics (MPs) have been documented in urban and remote locations across the globe. Further identification and quantification of MPs are required to determine how widespread they are in the environment. One of the most popular chemomet...
Rapid Classification of Coffee Varieties Using Single-Bean Hot Gas Extraction Ion-Mobility Spectrometry with Machine Learning [0.03%]
基于单一咖啡豆热载气提取离子移动谱的机器学习快速分类方法
Nathanael Aaron Prayoga,Chamarthi Maheswar Raju,Pawel L Urban
Nathanael Aaron Prayoga
Coffee is consumed by over one billion people daily, creating a high risk of adulteration where premium varieties are blended with inferior fillers. While various analytical techniques exist, they are often expensive and require labor-inten...
Data-Driven Electrochemistry Reveals the Impact of Hydrophobicity on Aptamer Cross-Reactivity [0.03%]
数据驱动电化学揭示疏水性对适配体交叉反应性的影响
Emily Carroll,Michael A Pence,Elizabeth Winterholler et al.
Emily Carroll et al.
Electrochemical aptamer-based (E-AB) biosensors offer a promising platform for reagentless detection of molecular targets, yet aptamer recognition can be limited by cross-reactivity, particularly for hydrophobic analytes such as steroid hor...
Selective Preconcentration and Mass Spectrometry Profiling of Charged Extracellular Modified Ribonucleosides by Borate Complexation and Temperature-Assisted Ionic Liquid Microextraction [0.03%]
硼酸络合和温度辅助离子液体微萃取选择性富集及电荷细胞外修饰核苷的质谱分析方法
Gabriella M Floro,Colin P McCarragher,Yu-Li Shih et al.
Gabriella M Floro et al.
Extracellular modified ribonucleosides have recently emerged as potent cell-to-cell signaling molecules, but their low abundance in complex biofluids has impeded progress toward understanding the full complement of their functions. A major ...
Transformation-Aware Molecular Networking for Interpretation of Untargeted LC-HRMS Data [0.03%]
转化感知分子网络法阐释非靶向LC-HRMS数据
Elena Ferri,Cristian Caprari,Maria Angela Vandelli et al.
Elena Ferri et al.
The rapid emergence of new psychoactive substances (NPS) and their extensive biotransformation challenge the reliability and interpretability of chemical measurements in forensic toxicology. Targeted analytical workflows offer high selectiv...
Fully 3D-Printed Sampling-to-Detection Electrochemical Platform for Point-of-Care Measurement of Salivary Uric Acid [0.03%]
用于唾液尿酸即时检测的全3D打印电化学生物传感平台
Ada Raucci,Wanda Cimmino,Cosimo Manna et al.
Ada Raucci et al.
This research presents an innovative all-in-one 3D-printed electrochemical biosensor for noninvasive detection of uric acid in saliva. Uric acid is a key biomarker for monitoring disorders such as gout and kidney disease as well as assessin...
Fully 3D-Printed Analytical Device Based on a Novel Floating Electrode Mechanism for Sweat Rate Acquisition [0.03%]
一种基于新型浮动电极机制的全3D打印分析设备用于汗液分泌率检测
Xing Xuan,Daniel Rojas,Silvia Pérez-Piñero et al.
Xing Xuan et al.
We present herein a unique analytical methodology based on a one-step, three-dimensional printed sensing device for measuring sweat rate noninvasively, which allows for the assessment of hydration levels. It comprises a multilayered constru...
From Gold to Polymer: Latex Bead-Assisted CRISPR-Cas12a Platform for Next-Generation Protein Diagnostics [0.03%]
从金纳米粒子到聚合物：CRISPR-Cas12a体系在下一代蛋白诊断中的应用
Rana Jahani,Jun Chen,Juanhua Kong et al.
Rana Jahani et al.
Sensitive and accurate detection of protein biomarkers in clinical samples is crucial for early disease diagnosis and monitoring treatment outcomes. Although gold nanoparticle (AuNP)-assisted CRISPR-Cas12a biosensors have shown promise, the...
A Theoretical Study of Clorsulon-Imprinted Polypyrrole: Modeling Complementary Cavity Formation and Rebinding of Clorsulon [0.03%]
有关聚吡咯-氯苯酚印迹的理论研究：氯苯酚互补空穴形成及再结合的模拟研究
Enayat Mohsenzadeh,Vilma Ratautaite,Agne Ramanaviciute et al.
Enayat Mohsenzadeh et al.
Clorsulon is highly toxic to aquatic organisms, including fish and invertebrates, and can have long-term adverse effects on the environment. It is commonly used in cattle, and residues excreted in dung can negatively affect dung-dependent i...
Structural Lipidomics Uncovers CC Location-Specific Lipid Signatures and the Response to Immune Checkpoint Inhibitor in dMMR/MSI‑H Colorectal Cancer [0.03%]
结构脂质组学揭示了dMMR / MSI-H结直肠癌中碳-碳位置特异性脂质特征及其对免疫检查点抑制剂的反应
Yiwei Tou,Wei Sun,Pai Liu et al.
Yiwei Tou et al.
Lipidomics offers valuable insights for cancer research. Paternò-Büchi (PB) reaction-based LC-MS/MS enables precise lipid structural resolution at the CC location level. Although mismatch repair-deficient or microsatellite instability-h...