Kinetic Characterization of F 420-Dependent Sugar-6-Phosphate Dehydrogenase from Cryptosporangium arvum [0.03%]
来源于Cryptosporangium arvum的F420依赖型糖磷酸脱氢酶的动力学性质研究
Alaa Aziz,Desiree R Czapski,Ravi Ramkissoon et al.
Alaa Aziz et al.
F 420-dependent glucose-6-phosphate dehydrogenase (FGD) catalyzes the oxidation of glucose-6-phosphate (G6P) to 6-phosphogluconolactone (6PG). Recent phylogenetic analyses have identified a new subclass of these enzymes, F 420-dependent sug...
Annalisa Invernizzi,Francesco Nai,Rajiv Kumar Bedi et al.
Annalisa Invernizzi et al.
N 6-Adenosine methylation is the most abundant modification of mRNA. The three members of the YTH domain family proteins (YTHDF1-3) recognize in the cytoplasm the m6A-RNA modification. We screened a library of about 500,000 fragments (i.e.,...
Overcoming Global Antifungal Challenges: Medical and Agricultural Aspects [0.03%]
全球抗真菌挑战：医学和农业方面面临的难题及应对策略
László Galgóczy
László Galgóczy
The prevalence of fungal infections and contamination has increased alarmingly over the past decade, posing a significant threat to human health and the food supply and negatively affecting welfare. This escalating concern is primarily attr...
Phenylalkyl Acetophenones and Anacardic Acids from Knema oblongifolia with Synthetic Analogues as Anti-infectives and Antibacterial Agents [0.03%]
来源于拟卫矛长果种的苯基丙酮和山胡椒酸及其抗感染和抗菌活性类似物的研究
Olivier Auguste Kirchhoffer,Jahn Nitschke,Alexandre Luscher et al.
Olivier Auguste Kirchhoffer et al.
The present study investigates the potential anti-infective and antibacterial properties of phenylalkyl acetophenones and anacardic acids isolated from the ethyl acetate extract of the leaves of Knema oblongifolia, along with synthetic deri...
Poly-Arginine Tails and Helical Segments of Natural Antimicrobial Peptides Display Concerted Action at Membranes for Enhanced Antimicrobial Effects [0.03%]
聚精氨酸尾部和天然抗菌肽中的螺旋片段在膜上协同作用以增强抗菌活性
Navleen Kaur,Kinjal Mondal,Megan E Mitchell et al.
Navleen Kaur et al.
Sequence motifs or patterns found in natural antimicrobial peptides (AMPs) have a great impact on their microbicidal activities. Here, through database inquiries and biological assays, we explore the enhanced antibacterial function associat...
Toward a Beautiful Amalgam: The Necessity of Heterogeneity in RNA Science and Research Culture [0.03%]
兼收并蓄：RNA科学研究文化异质性的必要性
Sudeshi M Abedeera,Mary Donnelly,James Hagerty et al.
Sudeshi M Abedeera et al.
RNA biology exemplifies functional heterogeneitydistinct RNA classes are expressed in tissue- and development-specific contexts, adopt dynamic conformational ensembles, and form intricate, context-dependent interactions with proteins and ...
Morpholinoethoxy-Substituted Cationic Metal-Free and Metallo Phthalocyanines: In Vitro Photodynamic Therapy Activities, PDT-Induced ROS Level Measurements, and Cellular Death Mechanism [0.03%]
N-甲氧基乙基化形态金属自由和金属洛通：体内光动力治疗活性，PDT引起的ROS水平测量和细胞死亡机制
Muge Serhatli,Seyma Isik,Ayfer Kalkan et al.
Muge Serhatli et al.
In this study, morpholinoethoxy-attached cationic tetra-substituted phthalocyanines (Pcs), including metal-free (HQH 2 Pc), zinc (HQZnPc), and indium (HQInPc) derivatives, were synthesized following established protocols. Their structures w...
Bridging Health Disparity Gaps in Alzheimer's Disease among Marginalized Populations: Clinical Proteomics as a Case Study [0.03%]
临床蛋白质组学为例探究阿尔茨海默病患者中的边缘群体的健康差距问题
Henry A Adeola,Renã A S Robinson
Henry A Adeola
Alzheimer's disease (AD) and AD-related dementias (ADRD) represent a significant health challenge, with a growing impact on marginalized populations who often experience inequities in overall healthcare access and outcomes. Many factors con...
Introducing the Tutorial Manuscript Type at the ACS Au Community Journals [0.03%]
美国化学学会Au社区期刊教程手稿类型的介绍
Squire J Booker,Stephanie L Brock,Xiangdong Li et al.
Squire J Booker et al.
In Vitro and In Vivo Antifungal Efficacy and Safety of the Ca Def2.1G27‑K44 Peptide against the Neglected and Drug-Resistant Pathogen [0.03%]
Ca Def2.1G27-K44肽对被忽视和耐药真菌的体内外抗真菌活性及安全性评估
Thomas Z A Guimarães,Érica O Mello,Douglas R Lucas et al.
Thomas Z A Guimarães et al.
The growing threat of fungal infections, driven by increasing drug resistance, has become a major global health concern. Candidiasis, a common human infection, is associated with high mortality, particularly in invasive cases. Among non- (N...