An update on the roles of transcription factor Ets1 in autoimmune diseases [0.03%]
转录因子Ets1在自身免疫病中的作用机制研究进展
Lee Ann Garrett-Sinha
Lee Ann Garrett-Sinha
Transcription factors are crucial to regulate gene expression in immune cells and in other cell types. In lymphocytes, there are a large number of different transcription factors that are known to contribute to cell differentiation and the ...
Amrita Nepalia,Sheryl Erica Fernandes,Harpreet Singh et al.
Amrita Nepalia et al.
The emergence of resistance to anti-infective agents poses a significant threat to successfully treating infections caused by bacteria. Bacteria acquire random mutations due to exposure to environmental stresses, which may increase their fi...
Daniel V Olivença,Jacob D Davis,Carla M Kumbale et al.
Daniel V Olivença et al.
Cystic fibrosis (CF) is widely known as a disease of the lung, even though it is in truth a systemic disease, whose symptoms typically manifest in gastrointestinal dysfunction first. CF ultimately impairs not only the pancreas and intestine...
Recent insights explaining susceptibility to endometriosis-From genetics to environment [0.03%]
近期解释子宫内膜异位症易感性的新见解-从遗传学到环境因素
Ana Sofia Pais,Teresa Almeida-Santos
Ana Sofia Pais
Endometriosis is a disease with a heterogeneous pathogenesis, explained by multiple theories, and also with a polymorphic presentation. The purpose of this literature review is to systematize the genetic, inflammatory, and environmental fac...
Alignment behavior of nerve, vascular, muscle, and intestine cells in two- and three-dimensional strategies [0.03%]
二维和三维策略下神经细胞、血管细胞、肌肉细胞和肠细胞的排列行为
Amir Jafari,Erfan Behjat,Haniyeh Malektaj et al.
Amir Jafari et al.
By harnessing structural hierarchical insights, plausibly simulate better ones imagination to figure out the best choice of methods for reaching out the unprecedented developments of the tissue engineering products as a next level. Construc...
MicroRNAs as powerful tool against COVID-19: Computational perspective [0.03%]
计算角度下的微小核糖核酸抗新冠肺炎的潜力分析
Ankur Omer
Ankur Omer
Severe acute respiratory syndrome coronavirus 2 is the virus that is responsible for the current pandemic, COVID-19 (SARS-CoV-2). MiRNAs, a component of RNAi technology, belong to the family of short, noncoding ssRNAs, and may be crucial in...
Astrocyte-mediated mechanisms contribute to traumatic brain injury pathology [0.03%]
星形胶质细胞介导的机制有助于创伤性脑损伤的病理变化
Carmen Muñoz-Ballester,Stefanie Robel
Carmen Muñoz-Ballester
Astrocytes respond to traumatic brain injury (TBI) with changes to their molecular make-up and cell biology, which results in changes in astrocyte function. These changes can be adaptive, initiating repair processes in the brain, or detrime...
Network medicine for patients' stratification: From single-layer to multi-omics [0.03%]
网络医学在患者的分类中应用：从单层到多组学
Manuela Petti,Lorenzo Farina
Manuela Petti
Precision medicine research increasingly relies on the integrated analysis of multiple types of omics. In the era of big data, the large availability of different health-related information represents a great, but at the same time untapped,...
Ana Filipa Ferreira,Maria Soares,Teresa Almeida-Santos et al.
Ana Filipa Ferreira et al.
Follicular microenvironment is paramount in the acquisition of oocyte competence, which is dependent on two interconnected and interdependent processes: nuclear and cytoplasmic maturation. Extensive research conducted in human and model sys...
Xinyue Zhao,Xiaomin Hu,Junjie Han et al.
Xinyue Zhao et al.
Fungi, being a necessary component of the gut microbiome, potentially have direct or indirect effects on the health and illness status of the host. The gut mycobiome is an inducer of the host's immunity, maintaining intestinal homeostasis, ...