Non-targeted effects of stereotactic radiotherapy: a review of the evidence coming from the clinical field [0.03%]
立体定向放疗的非靶向效应：来自临床领域的证据回顾
Angela Barillaro,Mara Caroprese,Chiara Feoli et al.
Angela Barillaro et al.
Background: Preclinical animal studies have demonstrated that radiation treatment (RT) can induce effects beyond the anatomical site of irradiation. Non-targeted effects of RT (NTER) have been sporadically reported in cli...
Multikinase and highly selective kinase inhibitors in the neoadjuvant treatment of patients with thyroid cancer [0.03%]
多激酶和高选择性激酶抑制剂在甲状腺癌新辅助治疗中的应用
Laura Valerio,Antonio Matrone
Laura Valerio
Multikinase inhibitors (MKIs) and highly selective tyrosine kinase inhibitors (HS-TKIs) positively impact the progression-free survival (PFS) of locally advanced and metastatic thyroid cancer cases. Moreover, disease-specific survival (DSS)...
Unmasking the potential: mechanisms of neuroinflammatory modulation by oncolytic viruses in glioblastoma [0.03%]
揭开潜在机制：溶瘤病毒在胶质母细胞瘤中对神经炎症的调节作用
Narimene Beder,Seyedeh Nasim Mirbahari,Mourad Belkhelfa et al.
Narimene Beder et al.
Glioblastoma, an aggressive and lethal brain tumor, presents enormous clinical challenges, including molecular heterogeneity, high recurrence rates, resistance to conventional therapies, and limited therapeutic penetration across the blood-...
Genomic alterations in the WNT/β-catenin pathway and resistance of colorectal cancer cells to pathway-targeting therapies [0.03%]
WNT/β-连环蛋白通路的基因组改变与结肠癌细胞对通路靶向疗法抵抗性
Ioannis A Voutsadakis
Ioannis A Voutsadakis
Aim: Colorectal cancer is the most prevalent gastrointestinal malignancy with limited therapeutic options in the metastatic setting. The WNT/β-catenin/adenomatous polyposis coli (APC) pathway is commonly deregulated in t...
Concomitant exposure to benzodiazepines during pembrolizumab-based therapy for advanced non-small-cell lung cancer: a propensity-score matched analysis of monitoring agency data [0.03%]
接受派姆单抗为基础的晚期非小细胞肺癌治疗的同时接触苯二氮平类药物：来自倾向性评分匹配分析监测机构数据的结果
Fabrizio Nelli,Enzo Maria Ruggeri,Antonella Virtuoso et al.
Fabrizio Nelli et al.
Aim: The interaction of concomitant benzodiazepine (BZD) exposure during immune checkpoint blockade has not been comprehensively investigated to date. This research aimed to determine the influence of BZD intake on the su...
Immunotherapy in cervical cancer: an innovative approach for better treatment outcomes [0.03%]
宫颈癌的免疫疗法：一种提高治疗效果的创新方法
Treshita Dey,Sushma Agrawal
Treshita Dey
Cervical cancer remains a significant global health challenge, ranking as the fourth most common cancer among women. Persistent infection with high-risk human papillomavirus (HPV) is the primary etiological factor, leading to immune evasion...
Herbal based nanoparticles as a possible and potential treatment of cancer: a review [0.03%]
基于草药的纳米粒作为癌症的一种可能的和潜在的治疗方法：一项回顾性研究
Roshan Yadav,Himmat Singh Chawra,Gaurav Dubey et al.
Roshan Yadav et al.
Cancer is the greatest cause of mortality worldwide. Various drug classes treat various cancers. Nanoformulations made from natural sources are being studied for treating several diseases, including cancer. Surgery, chemotherapy, immunother...
Ruiyang Lv,Zhenzhu Liu,Maoxin Lv et al.
Ruiyang Lv et al.
Bladder cancer is currently the most common malignant tumor of the urinary system. The traditional treatment methods for bladder cancer are mainly surgery, chemotherapy, radiotherapy, and targeted therapy; however, these treatment methods d...
Releasing the brakes: the role of immune checkpoint inhibitors in laryngeal cancer [0.03%]
释放制动：免疫检查点抑制剂在喉癌中的作用
Michail Athanasopoulos,Pinelopi Samara,Georgios Agrogiannis et al.
Michail Athanasopoulos et al.
Laryngeal cancer, a subtype of head and neck cancer, poses significant challenges due to its profound impact on essential functions such as speech and swallowing and poor survival rates in advanced stages. Traditional treatments-surgery, ra...
Elacestrant in hormone receptor-positive metastatic breast cancer: a post-hoc analysis [0.03%]
艾克司壮醇在激素受体阳性转移性乳腺癌中的作用：事后分析
Azza Sarfraz,Muzna Sarfraz,Faheem Javad et al.
Azza Sarfraz et al.
Background: Breast cancer is a leading cause of mortality in women. Hormone therapy plays a crucial role in treatment of hormone receptor-positive metastatic breast cancer. Elacestrant is a selective estrogen receptor deg...