Exploring recent advances in signaling pathways and hallmarks of uveal melanoma: a comprehensive review [0.03%]
探索脉络膜黑色素瘤信号通路及特征的近期进展：全面综述
Majid Banimohammad,Parsa Khalafi,Danial Gholamin et al.
Majid Banimohammad et al.
The purpose of this review was to provide a comprehensive review of the latest insights on the pathogenesis of uveal melanoma (UM) and its intracellular pathways. This article covers the epidemiology of UM, racial predispositions, cytogenet...
State-of-the-art photodynamic therapy for malignant gliomas: innovations in photosensitizers and combined therapeutic approaches [0.03%]
星界光动力疗法治疗恶性胶质瘤的研究进展：光敏剂和联合治疗方案的创新
Bruno A Cesca,Kali Pellicer San Martin,Matías D Caverzan et al.
Bruno A Cesca et al.
Glioblastoma (GBM), the most aggressive and lethal primary brain tumor, poses a significant therapeutic challenge due to its highly invasive nature and resistance to conventional therapies, including surgery, chemotherapy, and radiotherapy....
Eljie Isaak Bragasin,Justin Cheng,Lauren Ford et al.
Eljie Isaak Bragasin et al.
Small cell lung cancer (SCLC) is an aggressive tumor characterized by early metastasis and resistance to treatment, making it a prime target for therapeutic investigation. The current standard of care for frontline treatment involves a comb...
Evgeny N Imyanitov,Elena V Preobrazhenskaya,Natalia V Mitiushkina
Evgeny N Imyanitov
Although immune checkpoint inhibitors (ICIs) are widely used in clinical oncology, less than half of treated cancer patients derive benefit from this therapy. Both tumor- and host-related variables are implicated in response to ICIs. The pr...
Bladder cancer biomarkers [0.03%]
膀胱癌生物标志物
Dominik Godlewski,Dorota Bartusik-Aebisher,Sara Czech et al.
Dominik Godlewski et al.
Bladder cancer (BCa) is among the most frequently diagnosed urinary tract cancers, characterized by a high recurrence rate and significant clinical heterogeneity. Effective diagnosis and treatment of BCa demand continuous advancements in me...
Pancreatic cancer: failures and hopes-a review of new promising treatment approaches [0.03%]
胰腺癌：失败与希望 - 有前景的新治疗手段综述
Vittore Cereda,Mario Rosario D&#x;Andrea
Vittore Cereda
Pancreatic cancer is a challenging disease with limited treatment options and a high mortality rate. Just few therapy advances have been made in recent years. Tumor microenvironment, immunosuppressive features and mutational status represen...
A systematic review and meta-analysis of phase III randomized controlled trials to assess the risk of pneumonia, URTIs, and VTE in multiple myeloma patients treated with isatuximab [0.03%]
一项关于III期随机对照试验的系统回顾和荟萃分析，评估使用isatuximab治疗的多发性骨髓瘤患者患肺炎、上呼吸道感染和静脉血栓栓塞的风险
Daniel Thomas Jones,Hazem Aboaid,Ramaditya Srinivasmurthy et al.
Daniel Thomas Jones et al.
Background: Multiple myeloma (MM) is a hematologic malignancy characterized by the clonal proliferation of malignant plasma cells in the bone marrow, constituting approximately 13% of all hematologic malignancies. Isatuxi...
Luis Cabezón-Gutiérrez,Magda Palka-Kotlowska,Sara Custodio-Cabello et al.
Luis Cabezón-Gutiérrez et al.
Immunotherapy has revolutionized cancer treatment, yet its efficacy is frequently compromised by metabolic mechanisms that drive resistance. Understanding how tumor metabolism shapes the immune microenvironment is essential for developing e...
Implications of noncoding RNAs for cancer therapy: Are we aiming at the right targets? [0.03%]
非编码RNA对于癌症治疗的影响：我们的目标正确吗？
Amil Shah
Amil Shah
The discovery of oncogenes and tumor suppressor genes led to a better understanding of tumorigenesis, and prompted the development of molecularly targeted therapy. Over the past 30 years, many new drugs, which are primarily aimed at activat...
Shorter telomere length as a prognostic marker for survival and recurrence in breast cancer: a systematic review and meta-analysis [0.03%]
短的端粒长度作为乳腺癌生存率和复发预测指标的系统性综述及荟萃分析
Dhyas Munandar Arya Sasmita,Kavi Gilang Permana,Teguh Aryandono et al.
Dhyas Munandar Arya Sasmita et al.
Background: Telomere length is a potential prognostic biomarker in breast cancer, but its clinical utility remains uncertain due to inconsistent findings across the literature. This systematic review and meta-analysis aim...