An overview of the feasibility of nanomedicine in pancreatic cancer theranostics [0.03%]
纳米药物在胰腺癌诊疗中的可行性的概述
Kyriakos Kokkinogoulis,Aristomenis Kollas,David Simeonidis et al.
Kyriakos Kokkinogoulis et al.
Pancreatic ductal adenocarcinoma (PDAC) is among the top causes of cancer-induced mortality, frequently diagnosed too late to be treated effectively, due to the poor prognosis and the limited successful therapeutic options. Apart from the c...
Future perspectives: targeting fibroblast growth factor receptor 1 to enhance the efficacy of immunotherapy [0.03%]
前景展望：通过靶向成纤维细胞生长因子受体1提高免疫疗法的疗效
Ilya Tsimafeyeu
Ilya Tsimafeyeu
Fibroblast growth factor receptor 1 (FGFR1) plays a critical role in the progression of various cancers through its involvement in cell proliferation, survival, and differentiation. More recently, FGFR1 has been implicated in the mechanisms...
Role of exosomes in transforming growth factor-β-mediated cancer cell plasticity and drug resistance [0.03%]
外泌体在转化生长因子-β介导的癌细胞可塑性及耐药中的作用
Tatiana Ruksha,Nadezhda Palkina
Tatiana Ruksha
Transforming growth factor-β (TGF-β) is a multifunctional molecule with a dual role in carcinogenesis. Recent studies have demonstrated its various effects on cancer-related processes. However, the identification of TGF-β and TGF-β sign...
Mutational landscape of epidermoid carcinoma of the penis in a Brazilian cohort [0.03%]
巴西队列中阴茎鳞状细胞癌的突变特征
Renato Mendes Rossi De Lucca,Danielle Barbosa Brotto,Claudia Tarcila Gomes Sares et al.
Renato Mendes Rossi De Lucca et al.
Aim: Penile cancer (PeCa) is a rare malignancy strongly associated with poor genital hygiene and is more prevalent in regions with low socioeconomic status. PeCa accounts for approximately 2% to 4% of all male cancers in ...
A viral circular RNA in Kaposi's sarcoma-associated herpesvirus modulates viral and host gene expression during latent and lytic replication [0.03%]
一种Kaposi肉瘤疱疹病毒中的病毒来源的循环RNA通过调控潜伏期和增殖期的基因表达来影响病毒及宿主基因的表达
Soleil Torres,Vaibhav Jain,Daniel Stribling et al.
Soleil Torres et al.
Aim: Circular RNA (circRNA) is a class of noncoding, single-stranded RNA generated by backsplicing, a process where the 5' and 3' ends of an RNA are covalently joined. Virally encoded circRNAs have been identified in seve...
Mariana Chantre-Justino,Walter Meohas
Mariana Chantre-Justino
Musculoskeletal sarcomas represent heterogeneous and rare malignant bone and soft tissue tumors, affecting children and adults. Patients exhibiting poor clinical outcomes are often described, being associated with non-response to chemothera...
Circulating tumor cells: overcoming challenges of detecting a needle in a haystack [0.03%]
循环肿瘤细胞检测：克服大海捞针的挑战
Zhuldyz Myrkhiyeva,Kuanysh Seitkamal,Zhannat Ashikbayeva et al.
Zhuldyz Myrkhiyeva et al.
Circulating tumor cells (CTCs) are cancer cells that are detached from the primary and metastatic tumor site and invade the bloodstream. Most importantly, CTCs are the key players in the development of metastasis. As one of the main compone...
Jeanny B Aragon-Ching
Jeanny B Aragon-Ching
The role of circulating tumor DNA (ctDNA) in urothelial cancers is a rapidly evolving area of research. Urothelial cancer is the most common subtype of bladder cancer, and biomarkers that predict response or prognosticate outcomes have been...
Prognostic impact of biomarkers in PMBCL: rationale for early integration of immune checkpoint inhibitors [0.03%]
生物标志物在PMBCL中的预后影响：早期整合免疫检查点抑制剂的合理性
Yana K Mangasarova,Runiza R Abdurashidova,Natalya V Risinskaya et al.
Yana K Mangasarova et al.
Aim: This research aims to guide future strategies for personalized treatment of primary mediastinal large B-cell lymphoma (PMBCL), particularly to identify high-risk patients who may benefit from incorporating immune che...
Utility of CA-125 for diagnosis and prognosis of breast cancer: a systematic review [0.03%]
CA125在乳腺癌诊断和预后中的作用：系统性回顾分析研究
Zohre Momenimovahed,Afrooz Mazidimoradi,Leila Allahqoli et al.
Zohre Momenimovahed et al.
Background: Different tumor markers are utilized in the assessment of breast cancer. The function of these markers in assessing, tracking, and following up on breast cancer has drawn the interest of numerous researchers. ...