Racial disparities in hepatocellular carcinoma: a TCGA-based gene expression study of Caucasian and Asian populations [0.03%]
基于TCGA的基因表达研究中的白人和亚洲人群肝细胞癌的种族差异性分析
Muhammad Rezki Rasyak,Sri Jayanti,Cyrollah Disoma et al.
Muhammad Rezki Rasyak et al.
Aim: Hepatocellular carcinoma (HCC) displays both shared and ethnicity-specific molecular characteristics. Using transcriptomic data from The Cancer Genome Atlas (TCGA), we compared gene expression profiles between Asian ...
Bispecific antibodies in the treatment of epithelial ovarian, endometrial, and cervical cancer: an overview of current applications, challenges, and emerging opportunities [0.03%]
针对上皮性卵巢癌、子宫内膜癌和宫颈癌治疗的双特异性抗体：当前应用、挑战及发展机遇概述
Sara Parola,Ilaria Colombo
Sara Parola
Gynecological cancer remains one of the leading causes of mortality worldwide. Recent advances in genomic and molecular sequencing have significantly enhanced our understanding of the biological pathways that drive tumor progression and res...
Retraction: Anti-angiogenic effects of Moringa oleifera silver nanoparticles on endothelial cells: in vitro and ex vivo studies [0.03%]
撤稿：摩尔林嘉叶素对内皮细胞的抗血管生成作用：体外和植株外研究
Editorial Office
Editorial Office
[This retracts the article DOI: 10.37349/etat.2025.1002332.]. © Open Exploration Editorial Office 2025.
Differential molecular mechanisms of bortezomib sensitization to rhTRAIL in non-small cell lung cancer cell lines [0.03%]
硼替佐米对非小细胞肺癌细胞系rhTRAIL增敏的分子机制不同
Paweł Kochany,Janet H Stegehuis,Leonie H A M de Wilt et al.
Paweł Kochany et al.
Aim: TNF-related apoptosis-inducing ligand (TRAIL) is a promising targeted anti-cancer agent for several types of cancer, including non-small cell lung cancer (NSCLC). The proteasome inhibitor bortezomib can further poten...
Synergistic anticancer efficacy of optimized curcumin-piperine loaded magnetic nanoparticles for the treatment of colorectal cancer [0.03%]
一种优化的姜黄素-胡椒碱负载磁性纳米颗粒协同抗结直肠癌药效研究
Ritika Puri,Vimal Arora
Ritika Puri
Aim: The current study uses the depicted approach to synthesize curcumin-piperine loaded Poloxamer F-68 coated magnetic nanoparticles (CUR-PIP-F68-Fe3O4 NPs) to achieve a synergistic anti-cancer impact on an in vitro HCT-...
New approaches of green silver nanoparticles for cancer and biomedical applications: a review [0.03%]
绿色银纳米颗粒在癌症和生物医学应用中的新方法：综述
Puja Kumari,Khushi Quadri,Renu Kadian et al.
Puja Kumari et al.
The green synthesis of silver nanoparticles (AgNPs) has recently gained prominence as a sustainable and eco-friendly alternative to conventional physical and chemical methods. Utilizing biological entities such as plant extracts, bacteria, ...
Engineered nanocarriers for targeted lung cancer therapy: mechanistic innovations and recent clinical progress [0.03%]
工程化纳米载体在肺癌靶向治疗中的机制创新及最新临床进展
Heayyean Lee,Khadijah Sajid,Jeehoo Lee
Heayyean Lee
Lung cancer remains the leading cause of cancer mortality worldwide, with progress limited by tumor heterogeneity, drug resistance, and conventional therapy limitations. Nanotechnology-enabled drug delivery offers a transformative approach,...
Predictive value of 8-hydroxy-2'-deoxyguanosine and 8-nitroguanine production in radiation-induced skin damage after postoperative breast cancer radiotherapy [0.03%]
放射治疗后乳腺癌术后放射性皮肤损伤的预测标志物8-脱氧鸟苷和8-硝基鸟嘌呤的作用研究
Emmanouil K Verigos,Sofia Sagredou,Kosmas E Verigos et al.
Emmanouil K Verigos et al.
Aim: During radiation treatment, reactive oxygen species (ROS) and nitrogen species (RNS) are produced and, by extension, DNA adducts known as 8-hydroxy-2'-deoxyguanosine (8-OHdG) and 8-nitroguanine (8-NG), respectively. ...
Next-generation cancer vaccines: targeting cryptic and non-canonical antigens for precision immunotherapy [0.03%]
下一代癌症疫苗：靶向隐蔽及非经典抗原的精准免疫治疗
Anu Shibi Anilkumar,Sheena Mariam Thomas,Ramakrishnan Veerabathiran
Anu Shibi Anilkumar
Cancer immunotherapy has revolutionized oncology by harnessing the immune system to target tumor cells. Cancer vaccines that trigger immune responses specific to tumors are becoming more and more popular among new approaches. Nevertheless, ...
Metabolic plasticity drives specific mechanisms of chemotherapy and targeted therapy resistance in metastatic colorectal cancer [0.03%]
代谢可塑性驱动了转移性结直肠癌化疗和靶向治疗耐药的特定机制
Mariam Rojas,Malena Manzi,Sergio Madurga et al.
Mariam Rojas et al.
Microsatellite-stable metastatic colorectal cancer (MSS mCRC) is currently treated with chemotherapy and targeted agents based on RAS and BRAF mutational status. Although these therapies offer initial benefit, most patients rapidly develop ...