Exploration of Targeted Anti-tumor Therapy: a contribution to the development of targeted therapies [0.03%]
抗癌药物研发中基于生物标志物的精准医疗探索研究
Nicola Normanno,Graham Packham
Nicola Normanno
Katrin Sak
Katrin Sak
Compared to humans, plants can synthesize an extremely diverse array of chemical compounds, including phenolic acids, flavonoids, stilbenes, lignans, terpenoids, alkaloids, and many other types of secondary metabolites that have been demons...
Consequences of the impact of COVID-19 pandemic on breast cancer at a single Italian institution [0.03%]
意大利单中心机构COVID-19大流行对乳腺癌影响的后果
Daniele Ugo Tari,Rosalinda Santonastaso,Fabio Pinto
Daniele Ugo Tari
Aim: To evaluate the local impact of the coronavirus disease 2019 (COVID-19) pandemic on breast cancer (BC) care, with particular attention to the economical and psychological consequences of the possible delay of new dia...
Antonella Pietragalla,Francesca Ciccarone,Camilla Nero et al.
Antonella Pietragalla et al.
Poly-ADP-ribose polymerase inhibitors (PARP-I) represent one of the most attractive and promising class of biological agents studied both in relapsed ovarian cancer (OC) and in the advanced setting. The availability of this new class of dru...
An overview of the anti-cancer actions of Tanshinones, derived from Salvia miltiorrhiza (Danshen) [0.03%]
丹参茋类抗肿瘤作用研究进展
Irum Naz,Myriam Merarchi,Shanaya Ramchandani et al.
Irum Naz et al.
Tanshinone is a herbal medicinal compound described in Chinese medicine, extracted from the roots of Salvia miltiorrhiza (Danshen). This family of compounds, including Tanshinone IIA and Tanshinone I, have shown remarkable potential as anti...
Raimondo Di Liello,Flora Cimmino,Soraya Simón et al.
Raimondo Di Liello et al.
Immunotherapy has shifted the therapeutic landscape in thoracic cancers. However, assessment of biomarkers for patient selection and disease monitoring remain challenging, especially considering the lack of tissue sample availability for cl...
Understanding doxorubicin associated calcium remodeling during triple-negative breast cancer treatment: an in silico study [0.03%]
计算研究三阴性乳腺癌治疗过程中多柔比星致钙代谢异常的机制
Garhima Arora,Sumana Ghosh,Samrat Chatterjee
Garhima Arora
Aim: Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer with high heterogeneity, rapid progression, and paucity of treatment options. The most effective chemotherapeutic drug used to treat...
Analysis of DNA from liquid biopsy: new genetic biomarkers for cancer immunotherapy? [0.03%]
来自液体活检的DNA分析：癌症免疫治疗的新遗传生物标志物？
Carminia Maria Della Corte,Flora Cimmino,Floriana Morgillo
Carminia Maria Della Corte
Daniele Balducci,Claudia Quatraccioni,Antonio Benedetti et al.
Daniele Balducci et al.
Immune checkpoint inhibitors, such as cytotoxic T-lymphocyte antigen 4 inhibitors, programmed cell death 1 inhibitors and programmed cell death-ligand 1 inhibitors, have recently emerged as novel drugs in the anti-cancer therapy. Their use ...
Potential benefit of β-glucans as adjuvant therapy in immuno-oncology: a review [0.03%]
β-葡聚糖作为免疫肿瘤学辅助治疗的潜在益处：综述
Valeria Cognigni,Nicoletta Ranallo,Francesca Tronconi et al.
Valeria Cognigni et al.
Fungal compounds have long been used for centuries as food supplements. β-glucans have been identified as the most interesting molecules with beneficial effects in several chronic diseases. In vitro studies have shown that they are able to...