A primer on cancer-associated fibroblast mechanics and immunosuppressive ability [0.03%]
癌相关成纤维细胞力学和免疫抑制能力简介
Vanessa C Talayero,Miguel Vicente-Manzanares
Vanessa C Talayero
Cancer-associated fibroblasts (CAFs) are a major point of interest in modern oncology. Their interest resides in their ability to favor tumor growth without carrying genetic mutations. From a translational standpoint, they are potential the...
Yuhan Yang,Yimao Zhang,Yuan Li
Yuhan Yang
Artificial intelligence (AI) algorithms have been applied in abundant medical tasks with high accuracy and efficiency. Physicians can improve their diagnostic efficiency with the assistance of AI techniques for improving the subsequent pers...
Yuanzheng Huang,Zhihui Wang,Junni Gong et al.
Yuanzheng Huang et al.
Macrophages, as ubiquitous and functionally diverse immune cells, play a central role in innate immunity and initiate adaptive immunity. Especially, tumor-associated macrophages (TAMs) are crucial contributors to the tumorigenesis and devel...
Diagnostic value of liquid biopsy in the era of precision medicine: 10 years of clinical evidence in cancer [0.03%]
精确医学时代液体活检的诊断价值：癌症临床证据10年
Vincenza Caputo,Fortunato Ciardiello,Carminia Maria Della Corte et al.
Vincenza Caputo et al.
Liquid biopsy is a diagnostic repeatable test, which in last years has emerged as a powerful tool for profiling cancer genomes in real-time with minimal invasiveness and tailoring oncological decision-making. It analyzes different blood-cir...
Artificial intelligence fusion for predicting survival of rectal cancer patients using immunohistochemical expression of Ras homolog family member B in biopsy [0.03%]
基于活检标本中Ras同系物家族成员B免疫组化表达预测直肠癌患者生存的人工智能融合模型
Tuan D Pham,Vinayakumar Ravi,Bin Luo et al.
Tuan D Pham et al.
Aim: The process of biomarker discovery is being accelerated with the application of artificial intelligence (AI), including machine learning. Biomarkers of diseases are useful because they are indicators of pathogenesis ...
Crude extract of Ficus deltoidea Jack (FD) as a natural biological therapy [0.03%]
罗氏万寿藤的粗提取物作为天然生物疗法的研究
Mahmoud Dogara Abdulrahman
Mahmoud Dogara Abdulrahman
Aim: This study shows how important it is to coordinate research on Ficus deltoidea Jack (FD) so that results from different sources can be compared directly and a scientific conclusion can be made. ...
Encouraging probiotics for the prevention and treatment of immune-related adverse events in novel immunotherapies against malignant glioma [0.03%]
鼓励使用益生菌来预防和治疗新型恶性胶质瘤免疫疗法导致的免疫相关不良反应
Sayuri Yoshikawa,Kurumi Taniguchi,Haruka Sawamura et al.
Sayuri Yoshikawa et al.
Among the malignant tumors in the central nervous system (CNS), glioma is the most challenging tumor to the public society, which accounts for the majority of intracranial malignant tumors with impaired brain function. In general, conventio...
Mutant and non-mutant neoantigen-based cancer vaccines: recent advances and future promises [0.03%]
基于突变和非突变新抗原的癌症疫苗：近期进展与未来展望
Mohamad Omar Ashi,Fathia Mami-Chouaib,Stéphanie Corgnac
Mohamad Omar Ashi
Major advances in cancer treatment have emerged with the introduction of immunotherapies using blocking antibodies that target T-cell inhibitory receptors, such as programmed death-1 (PD-1) and cytotoxic T-lymphocyte-associated antigen-4 (C...
Evaluating immune response in vitro in a relevant microenvironment: a high-throughput microfluidic model for clinical screening [0.03%]
在相关的微环境中评估体外免疫反应：用于临床筛查的高通量微流体模型
Flora Doffe,Layla Fuoco,Judith Michels et al.
Flora Doffe et al.
Aim: Functional screening of new pharmaceutical compounds requires clinically relevant models to monitor essential cellular and immune responses during cancer progression, with or without treatment. Beyond survival, the e...
New phase therapeutic pursuits for targeted drug delivery in glioblastoma multiforme [0.03%]
多形性胶质母细胞瘤靶向药物传递的新阶段治疗追求
Manisha Singh,Divya Jindal,Vinayak Agarwal et al.
Manisha Singh et al.
Glioblastoma multiforme (GBM) is known as the most aggressive and prevalent brain tumor with a high mortality rate. It is reported in people who are as young as 10 years old to as old as over 70 years old, exhibiting inter and intra tumor h...