Abrahams Ocanto,Xabier Mielgo-Rubio,Javier Luna Tirado et al.
Abrahams Ocanto et al.
Oncology patients are more susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection due to hospital contact and an immunological system that can be compromised by antineoplastic therapy and supportive treatments...
Effect of coronavirus disease 2019 on diagnosis and treatment of hepatocellular carcinoma: a systematic review [0.03%]
2019冠状病毒病对肝细胞癌诊断和治疗影响的系统评价
Afrooz Mazidimoradi,Samane Sabet Birjandi,Hamid Salehiniya
Afrooz Mazidimoradi
Aim: Changes in strategies in the coronavirus disease 2019 (COVID-19) crisis and the imposing of restrictions have isolated many vulnerable patients including those with hepatocellular carcinoma (HCC) from routine medical...
Overcoming phenotypic switching: targeting protein-protein interactions in cancer [0.03%]
克服表型转换：癌症中蛋白质-蛋白质相互作用的靶向治疗
Christos Ladias,Pavlos Papakotoulas,Maria Papaioannou et al.
Christos Ladias et al.
Alternative protein-protein interactions (PPIs) arising from mutations or post-translational modifications (PTMs), termed phenotypic switching (PS), are critical for the transmission of alternative pathogenic signals and are particularly si...
Acryl-3,5-bis(2,4-difluorobenzylidene)-4-piperidone targeting cellular JUN proto-oncogene, AP-1 transcription factor subunit inhibits head and neck squamous cell carcinoma progression [0.03%]
丙烯-3,5-双（2,4-二氟苯基亚甲基）-4-哌啶酮靶向细胞JUN原癌基因，AP-1转录因子亚单位抑制头颈鳞状细胞癌进展
Levi Arnold,Juan Pineda Gomez,Michael Barry et al.
Levi Arnold et al.
Aim: Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer worldwide with a survival rate below fifty percent. Addressing meager therapeutic options, a series of small molecule inhibitors were sc...
A review on in silico virtual screening methods in COVID-19 using anticancer drugs and other natural/chemical inhibitors [0.03%]
针对新冠肺炎的抗癌药物及其他天然/化学抑制剂的虚拟筛选方法综述
Babak Sokouti
Babak Sokouti
The present coronavirus disease 2019 (COVID-19) pandemic scenario has posed a difficulty for cancer treatment. Even under ideal conditions, malignancies like small cell lung cancer (SCLC) are challenging to treat because of their fast devel...
Integration of signaling pathway and bromodomain and extra-terminal domain inhibition for the treatment of mutant Kirsten rat sarcoma viral oncogene homolog cancer [0.03%]
信号传导途径和溴结构域与末端外结构域抑制整合治疗哈泽致癌基因阳性的癌症
Gerhard Hamilton,Sandra Stickler,Barbara Rath
Gerhard Hamilton
Mutant Kirsten rat sarcoma viral oncogene homolog (KRAS) is now a drugable oncogenic driver and the KRAS G12C variant responds clinically to sotorasib and adagrasib that covalently block the cysteine of the active center and inhibit downstr...
Effect of vitamin D supplementation on inflammatory markers and total antioxidant capacity in breast cancer women using a machine learning technique [0.03%]
维生素D补充对乳腺癌患者炎症标志物和总抗氧化能力影响的机器学习研究
Marzieh Tahmasebi,Masoud Veissi,Seyed Ahmad Hosseini et al.
Marzieh Tahmasebi et al.
Aim: This study aimed to establish a learning system using an artificial neural network (ANN) to predict the effects of vitamin D supplementation on the serum levels of vitamin D, inflammatory factors, and total antioxida...
Molecular interaction of metastasis suppressor genes and tumor microenvironment in breast cancer [0.03%]
乳腺癌中转移抑制基因与肿瘤微环境的分子相互作用
Sathammai Sathappa Supuramanian,Sid Dsa,Sitaram Harihar
Sathammai Sathappa Supuramanian
Breast cancer (BC) is a leading cause of cancer-related deaths in women worldwide where the process of metastasis is a major contributor to the mortality associated with this disease. Metastasis suppressor genes are a group of genes that pl...
Biomarkers in renal cell carcinoma and their targeted therapies: a review [0.03%]
肾细胞癌的生物标志物及其靶向治疗研究进展（综述）
Shruti Gupta,Shamsher Singh Kanwar
Shruti Gupta
Renal cell carcinoma (RCC) is one of the most life-threatening urinary malignancies displaying poor response to radiotherapy and chemotherapy. Although in the recent past there have been tremendous advancements in using targeted therapies f...
Melatonin, BAG-1 and cortisol circadian interactions in tumor pathogenesis and patterned immune responses [0.03%]
褪黑激素、BAG-1和皮质醇的昼夜节律相互作用在肿瘤发生和发展模式化免疫反应中的作用
George Anderson
George Anderson
A dysregulated circadian rhythm is significantly associated with cancer risk, as is aging. Both aging and circadian dysregulation show suppressed pineal melatonin, which is indicated in many studies to be linked to cancer risk and progressi...