Exploring the function of myeloid cells in promoting metastasis in head and neck cancer [0.03%]
探究髓系细胞在促进头颈部癌症转移中的作用
Dakota Dike Dimegwu Okwuone,Deri Morgan,Gregory N Gan
Dakota Dike Dimegwu Okwuone
Head and neck cancer (HNC) is a challenging disease that lacks effective treatment, particularly in the cases that spread locoregionally and metastasize distantly, dramatically reducing patient survival rates. Expanding the understanding of...
Identification of lysyl oxidase as an adipocyte-secreted mediator that promotes a partial mesenchymal-to-epithelial transition in MDA-MB-231 cells [0.03%]
识别氧化酶作为脂肪细胞分泌的介质，可促进MDA-MB-231细胞的部分间质上皮转化的过程
Cassidy M Van Stiphout,Grant Kelly,Nikitha K Pallegar et al.
Cassidy M Van Stiphout et al.
Aim: Breast cancer (BC) is the most common cancer in women worldwide, where adiposity has been linked to BC morbidity. In general, obese premenopausal women diagnosed with triple-negative BC (TNBC) tend to have larger tum...
Zachary Hamel,Sierra Sanchez,David Standing et al.
Zachary Hamel et al.
Pancreatic cancer remains a serious and deadly disease, impacting people globally. There remain prominent gaps in the current understanding of the disease, specifically regarding the role of the signal transducer and activator of transcript...
DNA methylation modulates epigenetic regulation in colorectal cancer diagnosis, prognosis and precision medicine [0.03%]
DNA甲基化调节结肠癌诊断、预后和精准医学中的表观遗传调控
Jingxin Ye,Jianfeng Zhang,Weifeng Ding
Jingxin Ye
Colorectal cancer (CRC) is a multifaceted disease influenced by the interplay of genetic and environmental factors. The clinical heterogeneity of CRC cannot be attributed exclusively to genetic diversity and environmental exposures, and epi...
Early-stage triple negative breast cancer: the therapeutic role of immunotherapy and the prognostic value of pathological complete response [0.03%]
早期三阴性乳腺癌：免疫治疗的治疗作用和病理完全缓解的预后价值
Pierluigi De Santis,Martina Perrone,Chiara Guarini et al.
Pierluigi De Santis et al.
Triple negative breast cancer (TNBC) represents an aggressive disease associated with a high risk of recurrence after curative treatment and a poor prognosis in the metastatic setting. Chemotherapy was for years the only treatment available...
George Pears,Abhishek Mahajan,Anna Olsson-Brown et al.
George Pears et al.
Immunotherapy treatments for cancer are known to cause adverse thyroid events which present a diagnostic challenge to clinicians and radiologists. This case report highlights the importance of a high clinical index of suspicion and careful ...
Novel therapeutic strategies targeting myeloid-derived suppressor cell immunosuppressive mechanisms for cancer treatment [0.03%]
针对髓源性抑制细胞免疫抑制机制的新型癌症治疗策略
Eric Jou,Natasha Chaudhury,Fizza Nasim
Eric Jou
Cancer is the leading cause of death globally superseded only by cardiovascular diseases, and novel strategies to overcome therapeutic resistance against existing cancer treatments are urgently required. Myeloid-derived suppressor cells (MD...
The oncogenic role of hepatitis B virus X gene in hepatocarcinogenesis: recent updates [0.03%]
乙型肝炎病毒X基因在肝癌发生中的致癌作用：最近的更新
Agustiningsih Agustiningsih,Muhammad Rezki Rasyak,Turyadi et al.
Agustiningsih Agustiningsih et al.
Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancers with high mortality rate. Among its various etiological factors, one of the major risk factors for HCC is a chronic infection of hepatitis B virus (HBV). HBV...
Recent preclinical and clinical advances in radioimmunotherapy for non-Hodgkin's lymphoma [0.03%]
放射免疫治疗非霍奇金淋巴瘤的近期临床前和临床进展
Hiroki Goto,Yoshioki Shiraishi,Seiji Okada
Hiroki Goto
Radioimmunotherapy (RIT) is a therapy that combines a radioactive nucleotide with a monoclonal antibody (mAb). RIT enhances the therapeutic effect of mAb and reduces toxicity compared with conventional treatment. The purpose of this review ...
Tomas Koltai,Larry Fliegel
Tomas Koltai
Cells are separated from the environment by a lipid bilayer membrane that is relatively impermeable to solutes. The transport of ions and small molecules across this membrane is an essential process in cell biology and metabolism. Monocarbo...