Magnetite nanoparticles: an emerging adjunctive tool for the improvement of cancer immunotherapy [0.03%]
磁铁矿纳米颗粒：一种改善癌症免疫治疗的新兴辅助工具
Phoomipat Jungcharoen,Kunakorn Thivakorakot,Nachayada Thientanukij et al.
Phoomipat Jungcharoen et al.
Cancer immunotherapy has emerged as a groundbreaking field, offering promising and transformative tools for oncological research and treatment. However, it faces several limitations, including variations in cancer types, dependence on the t...
Alteration of glucose metabolism and expression of glucose transporters in ovarian cancer [0.03%]
卵巢癌中葡萄糖代谢及葡萄糖转运体表达的变化
Fatima Ben Ali,Zineb Qmichou,Mohamed Oukabli et al.
Fatima Ben Ali et al.
Aerobic glycolysis also known as the Warburg effect, remains a hallmark of various cancers, including ovarian cancer. Cancer cells undergo metabolic changes to sustain their tumorigenic properties and adapt to environmental conditions, such...
Hexachlorobenzene as a differential modulator of the conventional and metronomic chemotherapy response in triple negative breast cancer cells [0.03%]
六氯苯作为三阴性乳腺癌细胞常规化疗和间歇化疗反应的调节剂
Yamila Sanchez,Mariana Abigail Vasquez Callejas,Noelia Victoria Miret et al.
Yamila Sanchez et al.
Aim: Triple negative breast cancer (TNBC) is usually treated with high doses of paclitaxel, whose effectiveness may be modulated by the action of environmental contaminants such as hexachlorobenzene. High doses of paclita...
Joaquim Carreras,Rifat Hamoudi,Naoya Nakamura
Joaquim Carreras
Hematologists, geneticists, and clinicians came to a multidisciplinary agreement on the classification of lymphoid neoplasms that combines clinical features, histological characteristics, immunophenotype, and molecular pathology analyses. T...
Spheroids and organoids derived from colorectal cancer as tools for in vitro drug screening [0.03%]
体外药物筛选的结直肠癌类球体和器官体
Sahira Syamimi Ahmad Zawawi,Elyn Amiela Salleh,Marahaini Musa
Sahira Syamimi Ahmad Zawawi
Colorectal cancer (CRC) is a heterogeneous disease. Conventional two-dimensional (2D) culture employing cell lines was developed to study the molecular properties of CRC in vitro. Although these cell lines which are isolated from the tumor ...
Tri-specific killer engager: unleashing multi-synergic power against cancer [0.03%]
三特异性杀伤器扩增剂：释放多协同抗肿瘤力量
Peeranut Winidmanokul,Aussara Panya,Seiji Okada
Peeranut Winidmanokul
Cancer continues to be a global health concern, necessitating innovative solutions for treatment. Tri-specific killer engagers (TriKEs) have emerged as a promising class of immunotherapeutic agents, offering a multifaceted approach to cance...
Tumor metabolism in pheochromocytomas: clinical and therapeutic implications [0.03%]
嗜铬细胞瘤的肿瘤代谢：临床和治疗意义
Mohammad Sadiq Jeeyavudeen,Navin Mathiyalagan,Cornelius Fernandez James et al.
Mohammad Sadiq Jeeyavudeen et al.
Pheochromocytomas and paragangliomas (PPGLs) have emerged as one of the most common endocrine tumors. It epitomizes fascinating crossroads of genetic, metabolic, and endocrine oncology, providing a canvas to explore the molecular intricacie...
Improving single nucleotide polymorphisms genotyping accuracy for dihydropyrimidine dehydrogenase testing in pharmacogenetics [0.03%]
用于药物基因组学中二氢嘧啶脱氢酶检测的单核苷酸多态性分型准确性的提高
Annalaura Montella,Sueva Cantalupo,Giuseppe D&#x;Alterio et al.
Annalaura Montella et al.
Fluoropyrimidines, crucial in cancer treatment, often cause toxicity concerns even at standard doses. Toxic accumulation of fluoropyrimidine metabolites, culminating in adverse effects, can stem from impaired dihydropyrimidine dehydrogenase...
Emerging roles of type 1 innate lymphoid cells in tumour pathogenesis and cancer immunotherapy [0.03%]
1型先天淋巴细胞在肿瘤发生及癌症免疫治疗中的作用不容忽视
James Michael Verner,Harry Frederick Arbuthnott,Raghavskandhan Ramachandran et al.
James Michael Verner et al.
Innate lymphoid cells (ILCs) are the most recently discovered class of innate immune cells found to have prominent roles in various human immune-related pathologies such as infection and autoimmune diseases. However, their role in cancer wa...
CD99 tumor associated antigen is a potential target for antibody therapy of T-cell acute lymphoblastic leukemia [0.03%]
CD99肿瘤相关抗原是T细胞急性淋巴性白血病抗体治疗的潜在靶点
Kamonporn Kotemul,Watchara Kasinrerk,Nuchjira Takheaw
Kamonporn Kotemul
Monoclonal antibodies (mAbs) are an effective drug for targeted immunotherapy in several cancer types. However, so far, no antibody has been successfully developed for certain types of cancer, including T-cell acute lymphoblastic leukemia (...