Evaluation of molecular effects associated with apoptosis, tumour progression, angiogenesis and metastasis by a novel combination of drugs with ormeloxifene in triple negative breast cancer cells [0.03%]
评估奥美洛西芬与新药组合对三阴性乳腺癌细胞凋亡、肿瘤进展、血管生成和转移的分子效应
Shehna Sharaf,Sreelekshmi S,Saikant Regidi et al.
Shehna Sharaf et al.
Aim: To investigate the molecular effects of a novel combination [sertraline and plumbagin (comb) with ormeloxifene (Orm)] for anticancer activity in triple negative breast cancer cell line "MDA-MB-231". ...
Comparison of primary and passaged tumor cell cultures and their application in personalized medicine [0.03%]
原代肿瘤细胞培养和传代肿瘤细胞系在精准医疗中的比较及应用研究进展
Vladislava V Pipiya,Zarema E Gilazieva,Shaza S Issa et al.
Vladislava V Pipiya et al.
Passaged cell lines represent currently an integral component in various studies of malignant neoplasms. These cell lines are utilized for drug screening both in monolayer cultures or as part of three-dimensional (3D) tumor models. They can...
Immunotherapy in thymic epithelial tumors: tissue predictive biomarkers for immune checkpoint inhibitors [0.03%]
免疫检查点抑制剂的组织预后生物标志物预测胸腺上皮肿瘤的免疫疗法
Stefano Lucà,Marina Accardo,Severo Campione et al.
Stefano Lucà et al.
Thymic epithelial tumors (TETs) are rare malignant neoplasms arising in the thymus gland. Nevertheless, TETs, including thymomas (TMs), thymic carcinomas (TCs), and thymic neuroendocrine neoplasms (TNENs), are the most common mediastinal ma...
Jutatip Panaampon,Seiji Okada
Jutatip Panaampon
Primary effusion lymphoma (PEL) is a large B-cell neoplasm usually presenting as a serious effusion in body cavities without detectable tumor masses. It is an AIDS-related non-Hodgkin's lymphoma (HL) with human herpes virus 8 (HHV8)/Kaposi ...
Imaging of supratentorial ependymomas with radio-pathological correlation [0.03%]
放射病理相关的幕上室管膜瘤影像学表现
Arpita Sahu,Aditi Venkatesh,Aman Snehil et al.
Arpita Sahu et al.
Aim: Supratentorial ependymoma (STE) is a rare tumor with distinct genetic alterations, whose imaging features have been scarcely studied. This study aims to review the computed tomography (CT) and magnetic resonance imag...
Vanessa Patel,Sandra Casimiro,Catarina Abreu et al.
Vanessa Patel et al.
Breast cancer (BC) is the most prevalent malignancy affecting women worldwide, including Portugal. While the majority of BC cases are sporadic, hereditary forms account for 5-10% of cases. The most common inherited mutations associated with...
Chemotherapy related changes in cfDNA levels in squamous non-small cell lung cancer: correlation with symptom scores and radiological responses [0.03%]
化疗诱导的肺鳞癌患者游离DNA水平变化与症状评分及影像学疗效的关系
Nithiyanandan Ravi,Parul Gupta,Amanjit Bal et al.
Nithiyanandan Ravi et al.
Aim: There is limited data on prognostic value of baseline plasma cell free DNA (cfDNA) in advanced squamous non-small cell lung cancer (sq-NSCLC). This prospective observational study aimed to assess change in plasma cfD...
Shihao Shang,Lei Zhang,Kepu Liu et al.
Shihao Shang et al.
Bladder cancer (BC) is the tenth most common malignancy globally. Urothelial carcinoma (UC) is a major type of BC, and advanced UC (aUC) is associated with poor clinical outcomes and limited survival rates. Current options for aUC treatment...
Clinical relevance of circulating tumor DNA in ovarian cancer: current issues and future opportunities [0.03%]
循环肿瘤DNA在卵巢癌中的临床意义：当前问题和未来机遇
Elena Trevisi,Cristiana Sessa,Ilaria Colombo
Elena Trevisi
Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. Due to the lack of effective screening and early detection strategies, many patients with OC are diagnosed with advanced disease, where treatment is rarely curative. M...