Accelerating Catalysis Understanding via Large Language Model Data Extraction and Shallow Machine Learning Techniques [0.03%]
通过大型语言模型数据提取和浅层机器学习技术加速催化理解
Brianna R Farris,Kevin C Leonard
Brianna R Farris
Catalysis is inherently complex. The lack of precise knowledge available to experimental researchers about the microenvironment, catalytic sites, mechanisms, and changes that occur under reaction conditions has hindered the effectiveness of...
Hexafluoroisopropanol-Mediated Cascade Cyclization for Construction of α‑Amino-γ-spirolactones [0.03%]
六氟异丙醇介导的串联环化反应构建α-氨基酸-γ-螺内酯类化合物
Haoran Li,Fangting Huang,Claire Miesch et al.
Haoran Li et al.
Given the ubiquity of spirolactones in pharmaceutical agents, natural products, and small-molecule chemical probes, considerable research has been devoted to streamlining their synthesis. Yet, the preparation of α-amino-γ-spirolactones, w...
Designing Peptide Fossils That Model the Evolution of the Bacterial Ferredoxin Fold [0.03%]
设计模拟细菌铁氧还蛋白折叠进化的肽化石
Bhanu P Jagilinki,Ian Campbell,Alexei M Tyryshkin et al.
Bhanu P Jagilinki et al.
Electron transfer coupled to redox chemistry is at the heart of metabolism. The proteins responsible for moving electrons (protein electron carriers) must have emerged at the origin of life. The small iron-sulfur-binding bacterial ferredoxi...
Control of Conical Intersection Dynamics in CF3I Photodissociation via Halogen Bonding [0.03%]
通过卤素键控制CF3I光解离的锥形交叉点动力学
Dong Yan,Huimin Zhang,Fangfang Li et al.
Dong Yan et al.
The dynamics of conical intersections are critical in governing the diverse pathways of chemical reactions, especially in photoexcited polyatomic systems. However, the systematic control of conical intersection dynamics remains a formidable...
Joaquin Resasco
Joaquin Resasco
Electrolyte cations are conventionally viewed as inert spectators in electrocatalysis. However, a wealth of observations show that catalytic rates are often highly sensitive to cation identity. Despite their prevalence, these cation effects...
Enhancing the Efficacy, Utility, and Throughput of the Transcription Block Survival Peptide Library Screening Platform [0.03%]
增强转录阻断生存肽文库筛选平台的效力、实用性和通量
Andrew Brennan,T M Simon Tang,Jody M Mason
Andrew Brennan
Genetically encoded peptide library screening is a powerful strategy for discovering inhibitors of protein-protein and protein-DNA interactions. The Transcription Block Survival (TBS) assay enables the in vivo selection of peptides that ant...
AND Logic Gate-Based Dual-Specificity DNA Circuit for Isothermal HBV rcDNA Detection [0.03%]
一种基于与逻辑门的用于等温检测乙肝病毒rcDNA的双功能DNA电路
Jingyi Si,Yifan Gao,Zhenzhou Yang et al.
Jingyi Si et al.
The quantitative analysis of blood HBV DNA is essential for controlling the spread of HBV and improving the prognosis of individuals infected with the virus. Yet the HBV genome exhibits complex variation, such as multiple-site mutations for...
Cooperative Copper/Lipase Catalysis for the Chemoenzymatic Dynamic Kinetic Resolution (DKR) of Bis(hetero)arenols [0.03%]
协同铜/脂肪酶催化杂芳基醇的动态动力学拆分(DKR)
Kun Wang,Yao Peng,Dingkai Lou et al.
Kun Wang et al.
Chemoenzymatic dynamic kinetic resolution (DKR), which combines a metal racemization catalyst with an enzyme, has been demonstrated as an elegant solution to deliver centrally and axially chiral products from their racemates. Bis-(hetero)-a...
Unveiling Atomic-Level Synergy of Pt3Fe Alloy Nanoparticles and Fe Single Atoms for Enhanced Electrochemical Stability [0.03%]
揭开Pt3Fe合金纳米颗粒与单个铁原子的原子协同作用以增强电化学稳定性之谜
Wen Huang,Jiabao Nie,Zhiying Zheng et al.
Wen Huang et al.
The hybridization of single atom sites (SASs) and nanoparticles (NPs) demonstrates enhanced stability under acidic electrochemical environments when compared to their individual components; however, the underlying synergistic mechanisms rem...
Accurate Quantification of 45N2O with a Membrane Inlet Mass Spectrometer by Optimizing the Temperature of a Cold Trap [0.03%]
通过优化冷阱温度精确使用膜进样质谱测定45N2O数量化精度
Chunyi Kuang,Xiaomei Shen,Zhiming Qu et al.
Chunyi Kuang et al.
Membrane Inlet Mass Spectrometry (MIMS) is extensively applied in the study of nitrogen cycling processes. However, robust methods for the quantitative detection of N2O by this technique are still scarce. In this study, acidified azide was ...