Preclinical assessment of dual CYP26[A1/B1] inhibitor, DX308, as an improved treatment for keratinization disorders [0.03%]
CYP26[A1/B1]双重抑制剂DX308改善角化障碍性疾病治疗的临床前评估研究
J G S Veit,Y Poumay,D Mendes et al.
J G S Veit et al.
Background: Retinoid-based therapies are commonly used in the treatment of disorders of keratinization and other skin disorders but can result in non-specific effects and adverse reactions. Use of retinoic acid metabolism...
Psychosocial aspects of obesity in adults with psoriasis: A systematic review [0.03%]
成人银屑病肥胖患者的身心社会因素系统回顾
N T Pavlova,K Kioskli,C Smith et al.
N T Pavlova et al.
Background: Excess weight is a common (30%-40%) multifactorial concern that remains understudied in adults with psoriasis. Objectives: ...
Multi parametric biophysical assessment of treatment effects on xerotic skin [0.03%]
干燥皮肤治疗效果的多参数生物物理评估
H Stettler,J M Crowther,M Brandt et al.
H Stettler et al.
Background: Topical moisturizing products are widely used to alleviate the problems associated with xerotic skin. Their use affects many properties of the stratum corneum (SC) in a complex and interrelated manner. The ran...
Prevalence and treatment of vitamin K deficiency in paediatric patients with recessive dystrophic epidermolysis bullosa-severe subtype [0.03%]
维生素K缺乏在严重型交配性营养不良表皮松解症患儿中的患病率及治疗状况
N Yerlett,G Petrof,K Holsgrove et al.
N Yerlett et al.
Introduction: Patients with recessive dystrophic epidermolysis bullosa-severe subtype (RDEB-S) are at risk of vitamin K deficiency, potentially causing abnormal clotting, excessive bleeding, poor bone metabolism and abnor...
Sex disparity in skin carcinogenesis and potential influence of sex hormones [0.03%]
性别差异与皮肤致癌及性激素的潜在影响
V Collier,M Musicante,T Patel et al.
V Collier et al.
Background: Sex or gender disparity in skin cancer has been documented for a long time at the population level. UV radiation (UVR) is a common environmental risk for all three major types of skin cancer: cutaneous melanom...
M H Larsen,Å Hermansen,C R Borge et al.
M H Larsen et al.
Objective: To explore health literacy (HL) profiles within a cohort of people with psoriasis. A cluster approach identifies groups of individuals that have similar HL profiles. The method unmasks sub-groups with particula...
Efficacy and safety of secukinumab for the treatment of severe ABCA12 deficiency-related ichthyosis in a child [0.03%]
塞库珠单抗治疗严重ABCA12缺乏相关性鱼鳞病患儿的疗效和安全性
J Yogarajah,C Gouveia,J Iype et al.
J Yogarajah et al.
Background: Patients with severe autosomal recessive congenital ichthyosis (ARCI) show a T helper 17/interleukin 17 (Th17/IL17) skewing in their skin and serum, resembling the inflammatory profile of psoriatic patients. S...
Case Reports
Skin health and disease. 2021 May 3;1(2):e25. DOI:10.1002/ski2.25 2021
A case of hypereosinophilia with digital ischaemia successfully treated with intravenous prostaglandin E1 [0.03%]
静脉注射前列腺素E1治疗重度嗜酸细胞增生伴指端缺血一例报告
M Kaga,H Takeuchi,K Iwahara et al.
M Kaga et al.
In the therapeutic management of eosinophilic disorder, it is important to prevent hypereosinophilia (HE)-related organ damage even in the process of diagnosis. We describe here a unique clinical and histopathological findings of the patien...
Case Reports
Skin health and disease. 2021 May 3;1(2):e32. DOI:10.1002/ski2.32 2021
Can atopic eczema and psoriasis coexist? A systematic review and meta-analysis [0.03%]
特应性皮炎和银屑病能否共存？系统评价与荟萃分析
A Cunliffe,S Gran,U Ali et al.
A Cunliffe et al.
Importance: Previous studies report both coexistence and mutual exclusivity of atopic eczema (AE) and psoriasis, but these have not been appraised systematically. Knowledge of such disease association throws light on dise...