Efficacy and safety of secukinumab for the treatment of severe ABCA12 deficiency-related ichthyosis in a child
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Background: Patients with severe autosomal recessive congenital ichthyosis (ARCI) show a T helper 17/interleukin 17 (Th17/IL17) skewing in their skin and serum, resembling the inflammatory profile of psoriatic patients. Secukinum... ...