Unlocking the potential of AI: Machine learning and deep learning models for predicting carcinogenicity of chemicals [0.03%]
解锁人工智能的潜力：用于预测化学品致癌性的机器学习和深度学习模型
Wenjing Guo,Jie Liu,Fan Dong et al.
Wenjing Guo et al.
The escalating apprehension surrounding the carcinogenic potential of chemicals emphasizes the imperative need for efficient methods of assessing carcinogenicity. Conventional experimental approaches such as in vitro and in vivo assays, alb...
Understanding the fate of disinfection by-products in swimming pools: current empirical and mechanistic modeling insights [0.03%]
了解游泳池消毒副产物的归宿：当前实证和机制建模见解
Shaorong Chen,Zijian Li
Shaorong Chen
Disinfecting swimming pool water plays a crucial role in preventing the spread of harmful bacteria. However, the interaction between disinfectants and precursors can lead to the formation of potentially disinfection by-products (DBPs). Prol...
Primary Microplastics in the Ecosystem: Ecological Effects, Risks, and Comprehensive Perspectives on Toxicology and Detection Methods [0.03%]
生态系统中初级微塑料的生态效应、风险及毒理学和检测方法的综合透视
Pooja Singh,Gunjan Varshney,Raminder Kaur
Pooja Singh
Recent discoveries of microplastics in cities, suburbs, and even remote locations, far from microplastic source regions, have raised the possibility of long-distance transmission of microplastics in many ecosystems. A little is known scient...
Si Chen,Yuxi Li,Xilin Li et al.
Si Chen et al.
Increasing public interest has resulted in the widespread use of non-pharmaceutical cannabidiol (CBD) products. The sales of CBD products continue to rise, accompanied by concerns regarding unsubstantiated benefits, lack of product quality ...
Si Chen,Zhen Ren,Lei Guo
Si Chen
Since usnic acid was first isolated in 1844 as a prominent secondary lichen metabolite, it has been used for various purposes worldwide. Usnic acid has been claimed to possess numerous therapeutic properties, including antimicrobial, anti-i...
PERform: assessing model performance with predictivity and explainability readiness formula [0.03%]
基于预测性和可解释性评估模型性能的公式
Leihong Wu,Joshua Xu,Weida Tong
Leihong Wu
In the rapidly evolving field of artificial intelligence (AI), explainability has been traditionally assessed in a post-modeling process and is often subjective. In contrary, many quantitative metrics have been routinely used to assess a mo...
Xiaoqing Guo,Hannah Xu,Ji-Eun Seo
Xiaoqing Guo
There has been growing interest in the use of human-derived metabolically competent cells for genotoxicity testing. The HepaRG cell line is considered one of the most promising cell models because it is TP53-proficient and retains many char...
Evaluating the mode of action of perfluorooctanoic acid-induced liver tumors in male Sprague-Dawley rats using a toxicogenomic approach [0.03%]
采用毒性基因组学方法评估全氟辛酸诱导雄性斯普拉格-道利大鼠肝脏肿瘤的致病机理
Xilin Li,Zemin Wang,Qiangen Wu et al.
Xilin Li et al.
The mode of action (MOA) underlying perfluorooctanoic acid (PFOA)-induced liver tumors in rats is proposed to involve peroxisome proliferator-activated receptor α (PPARα) agonism. Despite clear PPARα activation evidence in rodent livers,...
Assessment of clinical chemistry and hematological parameters in female Sprague-Dawley rats following a 7-day oral exposure to three different species of Echinacea [0.03%]
口服三种不同的紫锥菊七天后对雌性Sprague-Dawley大鼠的临床化学和血液学参数评估
Suresh K Nagumalli,Joshua T Salley,Jeffrey D Carstens
Suresh K Nagumalli
Echinacea has grown in popularity due to its broad therapeutic benefits. Despite its popularity, comprehensive safety evaluations for three medicinal species are limited. In this study, female Sprague-Dawley rats received oral doses (0, 25,...
More about making profits or providing safe drinking water? A state-of-the-art review on sachet water contamination in Nigeria [0.03%]
更多关于盈利还是提供安全饮用水？尼日利亚封包水污染现状综述
Johnson C Agbasi,Arinze Longinus Ezugwu,Michael Ekuru Omeka et al.
Johnson C Agbasi et al.
Public health concerns on surface and groundwater contamination worldwide have increased. Sachet water contamination has also raised serious concerns across many developing countries. While previous studies attempted to address this issue, ...