Uncovering the nexus of human health hazards of nanoplastics, gut-dysbiosis and antibiotic-resistance [0.03%]
揭示纳米塑料的人类健康危害、肠道菌群失调和抗生素耐药性的关联
Prashant Sharma,Sakshi Dagariya,Shubham Sharma et al.
Prashant Sharma et al.
Nanoplastics (1-1000 nm) (NPs) represent a novel and insidious class of emerging contaminants with the potential to profoundly disrupt gut microbial ecology and accelerate the spread of antibiotic resistance two critical and converging thre...
An ecological study of Superfund contaminants and thyroid cancer incidence in the United States [0.03%]
美国受污染场地污染物与甲状腺癌发病率的生态学研究
Sara J Zaat,Mathilda Monaghan,Maaike van Gerwen
Sara J Zaat
Environmental contaminants potentially associated with thyroid cancer are found in Superfund sites, areas the United States Environmental Protection Agency (EPA) has listed for cleanup. This study investigated the association between thyroi...
Mutation accumulation following extended exposure of human HepaRG cells to a genotoxic carcinogen [0.03%]
人类HepaRG细胞长期接触基因毒致癌物后的突变积累
Xiaoqing Guo,Ji-Eun Seo,Jaime Miranda-Colon et al.
Xiaoqing Guo et al.
Accurately evaluating chemical risk may benefit from the development of human-relevant models capable of capturing the effects of treatments that closely mimic real-world environmental and pharmaceutical exposures. Building on our previous ...
Mechanisms of DNA repair and mutagenesis induced by acetaldehyde, acrolein, aristolochic acids, and vinyl chloride [0.03%]
乙醛、丙烯醛、 Aristolochic 酸和氯乙烯引起的DNA修复及突变机制
Kyle Jones,Emmaline Dye,Nyla Gilkes et al.
Kyle Jones et al.
Humans are continually exposed to a diverse array of environmental chemicals that can damage DNA and compromise genomic integrity. Among these genotoxic agents, acetaldehyde, acrolein, aristolochic acids, and vinyl chloride are particularly...
Assessing carcinogenic and mutagenic hazards in firefighting: a comprehensive review [0.03%]
评估消防领域的致癌和致突变危害：全面回顾
Radosław Makowski,Wioletta Rogula-Kozłowska,Andrzej Polanczyk
Radosław Makowski
This review aims to critically assess the carcinogenic and mutagenic risks associated with firefighting, with a focus on cancer incidence, cancer mortality and other chronic health outcomes. Firefighting is widely recognized as a high-risk ...
Potential anticancer effects and toxicity of flavones luteolin and apigenin in vivo [0.03%]
类黄酮芦丁和木犀草素的抗癌作用及毒性研究
Xilin Li,Yuxi Li,Si Chen et al.
Xilin Li et al.
Luteolin and apigenin, which are abundantly present in various vegetables, fruits, and herbs, have emerged as noteworthy candidates for therapeutic applications. Traditionally recognized for their anti-inflammatory and antioxidant activitie...
Understanding heavy metal accumulation in crops: sources, plant responses, tolerance mechanisms, and environmental effects [0.03%]
理解作物重金属积累：来源、植物响应、耐性机制及环境影响
Sagardeep Sinha,Achyuta Basak,Md Sabir Ahmed Mondol
Sagardeep Sinha
Heavy metals are nearly everywhere in the environment, though at low concentrations. They may come to the environment through anthropologinic or natural causes. Their primary means of naturally enriching soils come from the weathering of pa...
Yuan Le,Xilin Li,Xiaoqing Guo et al.
Yuan Le et al.
Black cohosh (Actaea racemosa L) has been utilized for centuries by Native Americans as a traditional herbal medicine. The rhizome and root extract from black cohosh (BCE) is one of the most popular herbal dietary supplements worldwide. Due...
Transgenerational effects of bisphenol S exposure on the development of experimental asthma [0.03%]
双酚S暴露对实验性哮喘发育的跨代效应
Terumi Midoro-Horiuti,Yoko Murakami,Kazuyo Kuzume et al.
Terumi Midoro-Horiuti et al.
Early exposure to bisphenol A (BPA) is associated with increased asthma prevalence. To examine the effects of the most widely used BPA substitute, bisphenol S (BPS), on the development of childhood asthma, we conducted the study using the m...
Genotoxicity of nanoparticles evaluated using the in vitro micronucleus assay, a review of recent data§ [0.03%]
微核实验在纳米毒理遗传毒性评价中的应用及展望
Alexander W Alund,Li Xia,Tao Chen
Alexander W Alund
The in vitro micronucleus assay is a well-known and established component of the standard genotoxicity test battery. The growing use of nanomaterials around the world along with human exposure to them has increased the need for risk assessm...