Genotoxic effects of atmospheric PAH and heavy metals: Interaction and mechanistic evidence - a narrative review [0.03%]
大气中的多环芳烃和重金属的遗传毒性：交互作用及机制证据-综述文章
Norberto Alarcón-Herrera,Sandra Gómez-Arroyo,Saúl Flores-Maya et al.
Norberto Alarcón-Herrera et al.
Environmental contaminants present a significant concern owing to their pervasive distribution and their capacity to induce molecular and cellular damage. Among these, polycyclic aromatic hydrocarbons and heavy metals are of particular impo...
Interactions between polystyrene-derived micro- and nanoplastics and the microbiota: a systematic review of multi-omics mouse studies [0.03%]
聚苯乙烯衍生的微塑料和纳米塑料与微生物群相互作用的系统评价：小鼠多组学研究综述
Deniz Özkan Vardar,Berzan Ekmen,Abdulhamit Çalı
Deniz Özkan Vardar
Micro- and nanoplastics (MNPs), especially polystyrene-derived particles (PS-MPs/PS-NPs), have become a growing concern due to their increasing presence in the environment and their proven biological toxicity. Although PS particles have bee...
A critical review of styrene and styrene-7,8-oxide genotoxicity literature: an update [0.03%]
苯乙烯和苯乙烯氧化物遗传毒性文献的批判性复习：更新版
Lynn H Pottenger,Marcy Banton,Wade T Barranco et al.
Lynn H Pottenger et al.
Recent studies investigating mutagenic/cytogenetic effects of styrene and styrene-7,8-oxide (SO) were reviewed to update published critical evaluations of these data from 2019. Transcriptomics studies relevant to styrene/SO genotoxicity wer...
Abiola Olawale Ilori,Naven Chetty
Abiola Olawale Ilori
South Africa's water resources are increasingly impacted by mining, industrial activity, and natural geology, raising concerns about radionuclide contamination. This review synthesizes peer-reviewed studies assessing radionuclide concentrat...
Environmental determinants of therapeutic drug failure: a systematic review of heavy metal-induced inefficacy [0.03%]
环境决定的治疗药物失效：重金属诱导的无效性的系统性回顾研究
James O Ibibama,Godswill J Udom,Rehoboth Uwaga et al.
James O Ibibama et al.
Therapeutic drug failure poses a significant global health burden, particularly in developing regions with high environmental toxicant exposure. While traditionally attributed to factors such as substandard drugs, genetic polymorphisms, and...
Uncovering the nexus of human health hazards of nanoplastics, gut-dysbiosis and antibiotic-resistance [0.03%]
揭示纳米塑料的人类健康危害、肠道菌群失调和抗生素耐药性的关联
Prashant Sharma,Sakshi Dagariya,Shubham Sharma et al.
Prashant Sharma et al.
Nanoplastics (1-1000 nm) (NPs) represent a novel and insidious class of emerging contaminants with the potential to profoundly disrupt gut microbial ecology and accelerate the spread of antibiotic resistance two critical and converging thre...
An ecological study of Superfund contaminants and thyroid cancer incidence in the United States [0.03%]
美国受污染场地污染物与甲状腺癌发病率的生态学研究
Sara J Zaat,Mathilda Monaghan,Maaike van Gerwen
Sara J Zaat
Environmental contaminants potentially associated with thyroid cancer are found in Superfund sites, areas the United States Environmental Protection Agency (EPA) has listed for cleanup. This study investigated the association between thyroi...
Mutation accumulation following extended exposure of human HepaRG cells to a genotoxic carcinogen [0.03%]
人类HepaRG细胞长期接触基因毒致癌物后的突变积累
Xiaoqing Guo,Ji-Eun Seo,Jaime Miranda-Colon et al.
Xiaoqing Guo et al.
Accurately evaluating chemical risk may benefit from the development of human-relevant models capable of capturing the effects of treatments that closely mimic real-world environmental and pharmaceutical exposures. Building on our previous ...
Mechanisms of DNA repair and mutagenesis induced by acetaldehyde, acrolein, aristolochic acids, and vinyl chloride [0.03%]
乙醛、丙烯醛、 Aristolochic 酸和氯乙烯引起的DNA修复及突变机制
Kyle Jones,Emmaline Dye,Nyla Gilkes et al.
Kyle Jones et al.
Humans are continually exposed to a diverse array of environmental chemicals that can damage DNA and compromise genomic integrity. Among these genotoxic agents, acetaldehyde, acrolein, aristolochic acids, and vinyl chloride are particularly...
Assessing carcinogenic and mutagenic hazards in firefighting: a comprehensive review [0.03%]
评估消防领域的致癌和致突变危害：全面回顾
Radosław Makowski,Wioletta Rogula-Kozłowska,Andrzej Polanczyk
Radosław Makowski
This review aims to critically assess the carcinogenic and mutagenic risks associated with firefighting, with a focus on cancer incidence, cancer mortality and other chronic health outcomes. Firefighting is widely recognized as a high-risk ...