Aromatase in the Human Brain [0.03%]
人脑中的芳香化酶
Iñigo Azcoitia,Pablo Mendez,Luis M Garcia-Segura
Iñigo Azcoitia
The aromatase cytochrome P450 (P450arom) enzyme, or estrogen synthase, which is coded by the CYP19A1 gene, is widely expressed in a subpopulation of excitatory and inhibitory neurons, astrocytes, and other cell types in the human brain. Exp...
Testosterone Therapy for the Treatment of Age-Related Hypogonadism: Risks with Uncertain Benefits [0.03%]
雄激素缺乏的治疗——获利尚不确定的风险
Christine P Nguyen,Mark Hirsch,Suresh Kaul et al.
Christine P Nguyen et al.
Testosterone replacement therapy has been approved in the United States since the 1950s for men with "classical" hypogonadism. These men have specific and well-recognized hypothalamic, pituitary, or testicular conditions leading to deficien...
Association of Leptin with Total and Free Testosterone: Results from the National Health and Nutrition Examination Surveys [0.03%]
脂瘦素与总睾酮和游离睾酮的关系：来自全国健康与营养调查的结果
Thiago Fernandes Negris Lima,Sirpi Nackeeran,Evgeniya Rakitina et al.
Thiago Fernandes Negris Lima et al.
Introduction: Obese men can have testosterone deficiency (TD) but the etiology is uncertain. Leptin is a 16-kDa protein produced primarily by adipose tissue and, therefore, is positively associated with the amount of body...