Accounting for Withdrawal of Life-Sustaining Treatment in the Analysis of Traumatic Brain Injury Studies [0.03%]
考虑撤除生命维持治疗的创伤性脑损伤研究的统计分析方法
Brian C Healy,Brian L Edlow,Yelena G Bodien
Brian C Healy
Studies that aim to evaluate outcomes after severe traumatic brain injury (TBI) must account for patients who die after withdrawal of life-sustaining treatment (WLST). If we are willing to assume that some of the patients who die of WLST mi...
Sleep Fragmentation as a Diagnostic Biomarker of Traumatic Brain Injury [0.03%]
睡眠片段化作为一种诊断脑震荡的生物标志物
Grant S Mannino,Christian R Baumann,Mark R Opp et al.
Grant S Mannino et al.
Sleep disturbances are among the most prevalent and persistent consequences of traumatic brain injury (TBI), yet they remain underutilized as clinical indicators of injury status. In this perspective, we propose that sleep fragmentation-def...
Liberal Versus Restrictive Transfusion Trigger after Acute Brain Injury: More than Just Higher Blood Oxygen Content [0.03%]
急性脑损伤后输血触发点的利弊：不仅仅是更高的血液携氧能力
Adrienne K Ho
Adrienne K Ho
Previous studies on restrictive versus liberal blood hemoglobin transfusion triggers in critically ill or cardiac surgery patients had established a paradigm favoring restrictive triggers. In contrast, the hemoglobin transfusion threshold i...
Comparative Effectiveness of Midazolam-Based Sedation on the Need for Intracranial Pressure Lowering Therapies in Traumatic Brain Injury [0.03%]
基于咪达唑仑镇静对创伤性脑损伤后降低颅内压治疗需求的影响研究
Rianne G F Dolmans,Giovanni Russo,James Anstey et al.
Rianne G F Dolmans et al.
Sedatives play an important role in the management of patients with severe traumatic brain injury (sTBI) in the intensive care unit (ICU). Benzodiazepines are common for sedation (midazolam-based) but have been discouraged for non-brain-inj...
Crossing the Valley of Death in Spinal Cord Injury: Learning from Successful Translators [0.03%]
脊髓损伤的“死亡之谷”：从成功的转化研究中学习经验
Vieri Failli,Stephen M Strittmatter,Martin E Schwab et al.
Vieri Failli et al.
A straightforward path to successful scientific translation remains uncharted, particularly in a complex progressive condition such as spinal cord injury (SCI), which affects multiple body functions simultaneously. Evolving regulatory requi...
Rebecca T Somach,Miranda M Lim,Akiva S Cohen
Rebecca T Somach
Traumatic Brain Injuries (TBIs) are known to cause a myriad of symptoms in patients. One common symptom after injury is sleep disruptions. One neuropeptide system has been studied repeatedly as a potential cause of sleep disruptions after T...
Temporal Dynamics of Retinal Inflammation Following Blast Exposure in a Ferret Model [0.03%]
爆炸伤后大耳白兔视网膜炎症的时程变化规律研究
Rex Jeya Rajkumar Samdavid Thanapaul,Chetan Pundkar,Gaurav Phuyal et al.
Rex Jeya Rajkumar Samdavid Thanapaul et al.
Blast-induced traumatic ocular injury (bTOI) is a major cause of vision loss in military personnel involved in recent combat operations. However, its underlying mechanisms remain poorly understood, hindering the development of effective tre...
Epidemiology of Spinal Cord Injury in British Columbia, Canada: 20 Years of Population-Based Administrative Data [0.03%]
加拿大不列颠哥伦比亚省脊髓损伤的流行病学：二十年基于人群的行政数据
Michael Bond,Aidan Beresford,Vanessa Noonan et al.
Michael Bond et al.
Traumatic spinal cord injury (TSCI) is a debilitating condition that can have significant effects on physical function and overall quality of life. Mechanisms of injury can vary from major trauma to low-energy falls. There has been a recent...
Feasibility and Acceptability of Telephone-Administered Traumatic Brain Injury Common Data Elements and the Rehabilitation Needs Survey in Community-Dwelling Adults Exposed to the United States Criminal Legal System [0.03%]
面向接触美国刑事司法系统的社区成人开展的电话管理性脑损伤通用数据要素和康复需求调查的可行性和可接受性研究
Casey LaDuke,Kabrianna Tamura,Micaela Linder et al.
Casey LaDuke et al.
Traumatic brain injury (TBI) is common among legally-impacted adults and has also been linked to negative outcomes throughout the criminal legal system. Despite this, relatively limited TBI research has focused on or even included legally-i...
Lessons Learned and Recommendations from a SCOPE Spinal Cord Injury Neurorestorative Clinical Trials Update [0.03%]
SCOPE脊髓损伤神经修复临床试验的经验与建议更新报告
Bethany R Kondiles,Sabhya Rana,David Weiner et al.
Bethany R Kondiles et al.
The Spinal Cord Outcomes Partnership Endeavors presented a clinical trials update (CTU) in collaboration with the International Spinal Research Trust as a precourse to their annual meeting. Selected trials adhered to a priori considerations...