Spinal Cord Injuries Secondary to Mountain Biking Accidents - A Cause for National Alarm [0.03%]
山地自行车事故所致脊髓损伤--全国应敲响警钟
William Chu Kwan,Pedram Laghaei,Harsh Kahlon et al.
William Chu Kwan et al.
While much attention in North America has been placed on hockey and other high impact sports as causes of spinal cord injury (SCI), over the past two decades, our Level 1 trauma center has experienced a much higher number of SCI from off-ro...
Associations of Plasma Lipids with Traumatic Brain Injury Outcomes: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study [0.03%]
血浆脂蛋白与创伤性脑损伤预后的相关性：TRICKS研究结果
Andrea L C Schneider,Benjamin L Brett,Sabrina Abbruzzese et al.
Andrea L C Schneider et al.
Hypocholesterolemia has been observed in acute trauma, but less is known about lipid levels in acute traumatic brain injury (TBI). Our objectives were to (1) compare day 1 post-injury lipid levels from individuals with acute TBI to orthoped...
Dynamic Epidural Monitoring of Spinal Cord Neural Conduction Using a Novel Implantable Electrodiagnostic Sensor: A Pre Clinical Study [0.03%]
一种新型可植入电诊断传感器动态监测脊髓神经传导的临床前研究
Babak Shadgan,Alexander Burden,Jocelyn Bégin et al.
Babak Shadgan et al.
To evaluate the feasibility and diagnostic sensitivity of a novel catheter-based epidural electrodiagnostic (EDX) system for real-time, segment-specific monitoring of spinal somatosensory conduction in a pre-clinical model of acute spinal c...
Blood Levels of Dendritic Cell Populations in Patients with Moderate to Severe Traumatic Brain Injury [0.03%]
中重度创伤性脑损伤患者血液中树突状细胞水平分布特征分析
Patrik Fridh,Ebba Katsler,Niklas Marklund et al.
Patrik Fridh et al.
Traumatic brain injury (TBI) leads to intracerebral inflammation involving resident microglial cells and astrocytes as well as invading peripheral dendritic cells (DCs), monocytes, and neutrophils. However, the profile of immune blood cells...
Mechanical Distention of Organotypic Hippocampal Slice Culture Membranes for High-Throughput In Vitro Modeling of Traumatic Brain Injury [0.03%]
机械性脑外伤的高通量体外建模及器官型海马切片培养膜的扩张研究
Julia Jagielo-Miller,Caleb Bailey,Samir Patel et al.
Julia Jagielo-Miller et al.
Traumatic brain injury (TBI) results from impact to the head that induces both primary and secondary injuries. Secondary injuries are characterized by downstream inflammation, metabolic dysfunction, and cell death manifest from the inflicti...
Letter to the Editor in Response to: Eagle SR, Henry RJ. Applying Dynamical Systems Theory to Improve Personalized Medicine Following Mild Traumatic Brain Injury. Neurotrauma Rep 2024 Jul 16;5(1):671-679; Doi: 10.1089/Neur.2024.0040 [0.03%]
致编辑的信：对Eagle SR和Henry RJ关于应用动力系统理论改善轻度脑外伤后个性化医疗文章的回应
Tim W McGlennon
Tim W McGlennon
Ryanodex Reduces Persistent Hippocampal Effects of Single Mild Traumatic Brain Injury in Rats [0.03%]
瑞安诺缓激肽染料木素减少单次轻度脑损伤的持久海马效应
Reed Berlet,Isabel Bear,Cassidy Kessinger et al.
Reed Berlet et al.
Traumatic brain injury (TBI) affects millions of individuals annually, with a 53% increase in emergency visits since 2006. Despite its prevalence, no FDA-approved treatments exist to mitigate brain damage or promote recovery. While repeated...
The Interaction of Sleep and Mood During Recovery from Mild Traumatic Brain Injury [0.03%]
轻度脑外伤恢复期的睡眠与情绪交互作用
Robin McGee,Melanie A Montoya,Jason Barber et al.
Robin McGee et al.
Insomnia and depression are common co-morbidities associated with mild traumatic brain injury (mTBI). Data from Transforming Research and Clinical Knowledge in TBI, a longitudinal cohort study of TBI and orthopedic controls (OTC), were used...
Muscle-Restricted Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Knockout Partially Corrects Muscle Contractility After Spinal Cord Injury in Mice [0.03%]
肌肉限制性烟酰胺腺嘌呤二核苷酸磷酸氧化酶4敲除部分纠正了脊髓损伤后小鼠的肌肉收缩力
Carlos A Toro,Rita De Gasperi,Abdurrahman Aslan et al.
Carlos A Toro et al.
Spinal cord injury (SCI) results in severe atrophy of skeletal muscle in paralyzed regions, and a decrease in the force generated by muscle per unit of cross-sectional area. Oxidation of skeletal muscle ryanodine 1 receptors (RyR1) reduces ...
MicroRNAs Detected in Whole Blood Following Traumatic Brain Injury Are Associated with Recovery 6 Months after Injury [0.03%]
创伤性脑损伤后外周血液检测到的microRNA与伤后6个月恢复有关
Rogan Magee,Junchao Shen,Alexa E Walter et al.
Rogan Magee et al.
Traumatic brain injury (TBI) is a heterogeneous disease from which incomplete recovery is unfortunately common. Biomarkers prognostic of future recovery are currently lacking. MicroRNAs (miRNAs), small noncoding RNAs, are attractive potenti...