The Interaction of Sleep and Mood During Recovery from Mild Traumatic Brain Injury [0.03%]
轻度脑外伤恢复期的睡眠与情绪交互作用
Robin McGee,Melanie A Montoya,Jason Barber et al.
Robin McGee et al.
Insomnia and depression are common co-morbidities associated with mild traumatic brain injury (mTBI). Data from Transforming Research and Clinical Knowledge in TBI, a longitudinal cohort study of TBI and orthopedic controls (OTC), were used...
Muscle-Restricted Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Knockout Partially Corrects Muscle Contractility After Spinal Cord Injury in Mice [0.03%]
肌肉限制性烟酰胺腺嘌呤二核苷酸磷酸氧化酶4敲除部分纠正了脊髓损伤后小鼠的肌肉收缩力
Carlos A Toro,Rita De Gasperi,Abdurrahman Aslan et al.
Carlos A Toro et al.
Spinal cord injury (SCI) results in severe atrophy of skeletal muscle in paralyzed regions, and a decrease in the force generated by muscle per unit of cross-sectional area. Oxidation of skeletal muscle ryanodine 1 receptors (RyR1) reduces ...
MicroRNAs Detected in Whole Blood Following Traumatic Brain Injury Are Associated with Recovery 6 Months after Injury [0.03%]
创伤性脑损伤后外周血液检测到的microRNA与伤后6个月恢复有关
Rogan Magee,Junchao Shen,Alexa E Walter et al.
Rogan Magee et al.
Traumatic brain injury (TBI) is a heterogeneous disease from which incomplete recovery is unfortunately common. Biomarkers prognostic of future recovery are currently lacking. MicroRNAs (miRNAs), small noncoding RNAs, are attractive potenti...
Mapping the Landscape of Diaschisis in Traumatic Brain Injury: A Scoping Review [0.03%]
外伤性脑损伤中 diaschisis 的范围：系统综述
Madison Evans,Cigdem Tosun,Ruchira M Jha et al.
Madison Evans et al.
Diaschisis is a phenomenon in which damage to one brain region leads to dysfunction in remote, yet functionally connected, areas. Although it has been well characterized in stroke, the complex, multifocal nature of traumatic brain injury (T...
PAR-1 Expression in Chronic Subdural Hematoma: Potential Association with Vascular Permeability [0.03%]
慢性硬膜下血肿中PAR-1的表达及其与血管通透性的潜在关系
Wataru Shimohigoshi,Hajime Takase,Hiromichi Iwashita et al.
Wataru Shimohigoshi et al.
Chronic subdural hematoma (CSDH) is a common neurosurgical disease in the elderly, characterized by inflammation, neovascularization, and increased vascular permeability. Although protease-activated receptor-1 (PAR-1) is known to regulate v...
Concomitant Traumatic Brain Injury Exacerbates Endotheliopathy in Patients with Spinal Cord Injury [0.03%]
脊髓损伤患者并发脑外伤加重内皮细胞病变
Shahab Hafezi,Miguel A Ruiz-Cardozo,Sarbani Ghosh et al.
Shahab Hafezi et al.
Neurotrauma can cause endothelial dysfunction, characterized by neurovascular barrier disruption, tissue edema, neuroinflammation, and coagulation abnormalities, all of which may contribute to secondary injuries and worsened clinical outcom...
Hugh McCloskey,Carolyn Beth McNabb,Pedro Luque Laguna et al.
Hugh McCloskey et al.
Repetitive, sub-concussive head impacts have been associated with increased chronic traumatic encephalopathy (CTE) incidence. CTE diagnosis traditionally relies on postmortem examination, which limits precise correlation between cause and e...
Soluble Glycoprotein 130Fc Reduces Controlled Cortical Impact-Induced Cognitive Deficits in Rats [0.03%]
可溶性糖蛋白130Fc减轻控制性皮层撞击诱导的大鼠认知缺陷
Ashley L Russell,Emma G Dimeo,Anisha Mandava et al.
Ashley L Russell et al.
Traumatic brain injury (TBI) can lead to cognitive dysfunction, with underlying mechanisms poorly understood. Interleukin (IL)-6, particularly via soluble IL-6 receptor (sIL-6R) trans-signaling, can exacerbate neurodegeneration. Soluble gly...
Prior Psychiatric Disorder and Post-Traumatic Stress, Depressive and Anxiety Disorder after Traumatic Brain Injury with Glasgow Coma Scale Score 13-15: A TRACK-TBI Study [0.03%]
昏迷评分13至15分的脑创伤患者的既往精神疾病状况及其对创伤后应激、抑郁和焦虑障碍的影响：TRACK-TBI项目研究结果
Shawn R Eagle,Lindsay D Nelson,Joseph T Giacino et al.
Shawn R Eagle et al.
The most consistent risk factor for developing psychiatric problems post-traumatic brain injury (TBI) is a preexisting psychiatric disorder, but many studies have reported that psychiatric disorders can occur de novo following "mild" TBI. T...
Assessment of Neurobehavioral Performance and Markers of Synaptic Vesicle Trafficking in an Alpha-Synuclein Knockout Mouse Model after Controlled Cortical Impact Injury [0.03%]
基于受控皮层冲击损伤的α-突触核蛋白基因敲除小鼠的行为评估及突触囊泡转运标志物的变化规律研究
Eleni H Moschonas,Zachary Rohde,Madison Parry et al.
Eleni H Moschonas et al.
Traumatic brain injury (TBI) is associated with significant deficits across cognitive, emotional, and somatic functions, contributing to reduced quality of life for TBI survivors. Synaptic vesicle cycling, crucial for neurotransmitter relea...