Sonic Hedgehog Signaling Promotes Peri-Lesion Cell Proliferation and Functional Improvement after Cortical Contusion Injury [0.03%]
Sonic hedgehog信号促进皮层撞击损伤后 peri-lesion 区细胞增殖及功能恢复
Ashley K Pringle,Elshadaie Solomon,Benjamin J Coles et al.
Ashley K Pringle et al.
Traumatic brain injury (TBI) is a leading cause of death and disability globally. No drug treatments are available, so interest has turned to endogenous neural stem cells (NSCs) as alternative strategies for treatment. We hypothesized that ...
Characterization of the Jet-Flow Overpressure Model of Traumatic Brain Injury in Mice [0.03%]
小鼠创伤性脑损伤的喷射流冲击超压模型的特征分析
Min-Kyoo Shin,Edwin Vázquez-Rosa,Coral J Cintrón-Pérez et al.
Min-Kyoo Shin et al.
The jet-flow overpressure chamber (OPC) has been previously reported as a model of blast-mediated traumatic brain injury (bTBI). However, rigorous characterization of the features of this injury apparatus shows that it fails to recapitulate...
Associations between Traumatic Brain Injury, Drug Abuse, Alcohol Use, Adverse Childhood Events, and Aggression Levels in Individuals with Foster Care History [0.03%]
童年受虐经历、药物滥用、饮酒与寄养历史个体脑损伤及攻击性行为之间的关系研究
Michael D Cusimano,Stanley Zhang,Grace Huang et al.
Michael D Cusimano et al.
Nearly 50,000 Canadian children live in foster care. Compared with their peers, foster children experience greater independence and decreased guidance, predisposing them to harmful exposures such as traumatic brain injury (TBI), illicit dru...
Hypertonic Saline for Moderate Traumatic Brain Injury: A Scoping Review of Impact on Neurological Deterioration [0.03%]
高渗盐水治疗中度创伤性脑损伤：对神经功能恶化影响的系统评价研究
Heather Rossong,Mohammed Hasen,Bilal Ahmed et al.
Heather Rossong et al.
Hypertonic saline (HTS) is a commonly administered agent for intracranial pressure (ICP) control in traumatic brain injury (TBI). The literature on its use is mainly in moderate/severe TBI where invasive ICP monitoring is present. The role ...
Robotic Semi-Automated Transcranial Doppler Assessment of Cerebrovascular Autoregulation in Post-Concussion Syndrome: Methodological Considerations [0.03%]
机器人半自动经颅多普勒检查脑血管自身调节在轻微创伤性脑损伤后综合征中的应用：方法学考虑因素
Danyal Z Khan,Michal M Placek,Peter Smielewski et al.
Danyal Z Khan et al.
Post-concussion syndrome (PCS) refers to a constellation of physical, cognitive, and emotional symptoms after traumatic brain injury (TBI). Despite its incidence and impact, the underlying mechanisms of PCS are unclear. We hypothesized that...
P-glycoprotein Expression Is Upregulated in a Pre-Clinical Model of Traumatic Brain Injury [0.03%]
创伤性脑损伤动物模型中p-糖蛋白的表达上调
Sydney M Vita,John B Redell,Mark E Maynard et al.
Sydney M Vita et al.
Athletes participating in contact sports are at risk for sustaining repeat mild traumatic brain injury (rmTBI). Unfortunately, no pharmacological treatment to lessen the pathophysiology of brain injury has received U.S. Food and Drug Admini...
Differential Change in Oculomotor Performance among Female Collegiate Soccer Players versus Non-Contact Athletes from Pre- to Post-Season [0.03%]
基于季节变换的女子足球运动员与非身体接触类运动员眼动表现差异性分析
Virginia T Gallagher,Prianka Murthy,Jane Stocks et al.
Virginia T Gallagher et al.
Sensitive and reliable tools are needed to evaluate potential behavioral and cognitive changes following head impact exposure in contact and collision sport participation. We evaluated change in oculomotor testing performance among female, ...
The Impact of Vasopressor and Sedative Agents on Cerebrovascular Reactivity and Compensatory Reserve in Traumatic Brain Injury: An Exploratory Analysis [0.03%]
血管加压药和镇静剂对创伤性脑损伤患者脑血管反应性和代偿储备的影响：一项探索性分析
Logan Froese,Joshua Dian,Carleen Batson et al.
Logan Froese et al.
The impact of vasopressor and sedative drugs on cerebrovascular reactivity in traumatic brain injury (TBI) remains unclear. The aim of this study was to evaluate the impact of changes of doses of commonly administered sedation (i.e., propof...
Best Practices for Progressive Return to Activity after Concussion: Lessons Learned from a Prospective Study of U.S. Military Service Members [0.03%]
一项关于美国现役军人的前瞻性研究得出的脑震荡后逐步恢复活动的最佳实践教训
Mark L Ettenhofer,Rosemay A Remigio-Baker,Jason M Bailie et al.
Mark L Ettenhofer et al.
Primary care providers can play a crucial role in the clinical management of concussion. However, many providers lack up-to-date information about best practices for rest and return to activity after these injuries. Most research on this to...
Cerebrovascular Response to Propofol, Fentanyl, and Midazolam in Moderate/Severe Traumatic Brain Injury: A Scoping Systematic Review of the Human and Animal Literature [0.03%]
异丙酚、芬太尼和咪达唑仑对中重度创伤性脑损伤患者脑血管反应的影响：人类及动物文献综述式系统评价
Logan Froese,Joshua Dian,Carleen Batson et al.
Logan Froese et al.
Intravenous propofol, fentanyl, and midazolam are utilized commonly in critical care for metabolic suppression and anesthesia. The impact of propofol, fentanyl, and midazolam on cerebrovasculature and cerebral blood flow (CBF) is unclear in...