Effects of Acute Probenecid Administration on Histopathological and Functional Outcomes after Spinal Cord Injury in Rats [0.03%]
急性 probenecid给药对脊髓损伤后大鼠的组织病理学和功能预后的影响
Toru Asari,Sunao Tanaka,Damien D Pearse et al.
Toru Asari et al.
Spinal cord injury (SCI) triggers an inflammatory response that is partially mediated by the inflammasome and the production of pro-inflammatory cytokines. We have previously shown that pannexin-1 is involved in the activation of the inflam...
The Injection of Ghrelin (OXE-103) Improves Subacute Concussion Symptom Burden and Quality of Life [0.03%]
胃泌素神经调节肽(OXE-103)注射改善亚急性脑震荡症状和生活质量
Michael Rippee,Michael Wyand,Jamie Chen et al.
Michael Rippee et al.
Concussions remain the leading form of traumatic brain injury. Despite this, there is a paucity of pharmacologic and evidence-based treatments. The objective of this study was to investigate the benefit of Ghrelin (OXE-103) as a novel treat...
IGF-1 as a Biomarker for Symptom Severity in Adult Traumatic Brain Injury: Evidence from an Observational Study [0.03%]
一项观察性研究：生长因子-1可作为成人创伤性脑损伤症状严重程度的生物标志物的证据
Justin Weppner,Kimberly Rosenthal,Jennifer Bath et al.
Justin Weppner et al.
Traumatic brain injury (TBI)-related growth hormone deficiency is often undertreated, despite documented physical, metabolic, and neuropsychiatric effects. Insulin-like growth factor (IGF-1), with neuroreceptors located in brain regions res...
Quiet Stance Postural Control in Women Who Have a History of Brain Injury from Intimate Partner Violence: A Preliminary Study [0.03%]
既往遭受过亲密伴侣暴力的脑损伤女性在静息站立时的姿势控制：初步研究
Bradi R Lorenz,Shambhu P Adhikari,Jonathan D Smirl et al.
Bradi R Lorenz et al.
Intimate partner violence (IPV) frequently results in brain injury (IPV-BI) among survivors, with potential long-term effects for both physical and psychological health. This study aimed to examine the impact of chronic IPV-BI on postural c...
Progressive Remote Axonal Degeneration Following Spinal Cord Injury: A Histological and MRI Study [0.03%]
脊髓损伤后的轴突进行性远程变性的组织学和MRI研究
Gergely David,Alice Motovylyak,Felix Schlegel et al.
Gergely David et al.
In acute human spinal cord injury (SCI), magnetic resonance imaging (MRI) reveals progressive neuroanatomical changes at the lesion site and in remote regions. Here, we aimed to elucidate the structural underpinnings of these neuroanatomica...
Early-Life Mild Traumatic Brain Injury Alters Neurodevelopment and Behavior in Mice [0.03%]
小鼠早期轻度脑创伤影响神经发育和行为反应
Rachel R Corrigan,Anna O Lanier,Emily S Dresher et al.
Rachel R Corrigan et al.
Approximately 280 children per 100,000 experience closed-head injuries each year, with over 80% being mild in severity. While most children with mild injuries do not require admission to a hospital and recover well over time, some children ...
Exploring the Impact of Mitoquinone Supplementation on Glycan Profiles in a Repeated Mild Traumatic Brain Injury Mouse Model [0.03%]
探究反复轻度创伤性脑损伤小鼠模型中线粒体药物MitoQ对糖链图谱影响的研究
Mona Goli,Akeem Sanni,Sakshi Gautam et al.
Mona Goli et al.
Traumatic brain injury (TBI) represents a significant cause of injury-related deaths and disabilities. Repeated exposure to mechanical impact can lead to metabolic and ionic imbalance, which can cause oxidative stress and worsen the cellula...
Jesse A Stokum,Riccardo Serra,Nicole Gorny et al.
Jesse A Stokum et al.
Spinal cord injury (SCI) remains a major unsolved problem that permanently impairs the lives of innumerable individuals worldwide. Although advances in the basic, pre-clinical and clinical sciences of SCI hold promise for patients, clinicia...
Epidemiology of Traumatic Cervical Spinal Cord Injury in Southeast Norway [0.03%]
挪威东南部创伤性颈椎脊髓损伤的流行病学研究
Mona Strøm,Jalal Mirzamohammadi,Thomas Glott et al.
Mona Strøm et al.
A traumatic cervical spinal cord injury (cSCI) is a severe consequence of trauma to the cervical spine with high mortality and morbidity rates. Epidemiological studies of traumatic cSCIs are necessary for planning preventive measures and he...
Long-Term Survival for Traumatic Spinal Cord Injury in British Columbia, Canada: A Retrospective Evaluation of 20 Years of Linked Health Care Data [0.03%]
加拿大不列颠哥伦比亚省创伤性脊髓损伤的长期生存率：链接医疗保健数据的20年回顾性评估
Michael Bond,Aidan Beresford,Vanessa Noonan et al.
Michael Bond et al.
Patients living with traumatic spinal cord injury (TSCI) have seen many improvements in care and treatment, but life expectancy still falls below the general population. Measuring long-term survival rates and characterizing causes of death ...