Deep learning in spatial transcriptomics: Learning from the next next-generation sequencing [0.03%]
深度学习在空间转录组学中的应用：从下一代测序技术中学习
A Ali Heydari,Suzanne S Sindi
A Ali Heydari
Spatial transcriptomics (ST) technologies are rapidly becoming the extension of single-cell RNA sequencing (scRNAseq), holding the potential of profiling gene expression at a single-cell resolution while maintaining cellular compositions wi...
Optical trapping with holographically structured light for single-cell studies [0.03%]
用于单细胞研究的光镊全息结构光捕获技术
Moosung Lee,Hervé Hugonnet,Mahn Jae Lee et al.
Moosung Lee et al.
A groundbreaking work in 1970 by Arthur Ashkin paved the way for developing various optical trapping techniques. Optical tweezers have become an established method for the manipulation of biological objects, due to their noninvasiveness and...
Jiren Luo,Jiangfeng Chen,Yaoge Huang et al.
Jiren Luo et al.
Natural biological materials are programmed by genetic information and able to self-organize, respond to environmental stimulus, and couple with inorganic matter. Inspired by the natural system and to mimic their complex and delicate fabric...
Microfluidic approaches for producing lipid-based nanoparticles for drug delivery applications [0.03%]
用于药物输送的基于脂质的纳米颗粒的微流体生产方法
Caterina Piunti,Elisa Cimetta
Caterina Piunti
The importance of drug delivery for disease treatment is supported by a vast literature and increasing ongoing clinical studies. Several categories of nano-based drug delivery systems have been considered in recent years, among which lipid-...
Stability and robustness properties of bioelectric networks: A computational approach [0.03%]
生物电网络的稳定性和健壮性属性：一种计算方法
Joel Grodstein,Michael Levin
Joel Grodstein
Morphogenesis during development and regeneration requires cells to communicate and cooperate toward the construction of complex anatomical structures. One important set of mechanisms for coordinating growth and form occurs via developmenta...
Forgotten but not gone: Particulate matter as contaminations of mucosal systems [0.03%]
被遗忘但并未消失：颗粒物对粘膜系统的污染问题
Matthias Marczynski,Oliver Lieleg
Matthias Marczynski
A decade ago, environmental issues, such as air pollution and the contamination of the oceans with microplastic, were prominently communicated in the media. However, these days, political topics, as well as the ongoing COVID-19 pandemic, ha...
Self-organization of whole-gene expression through coordinated chromatin structural transition [0.03%]
染色质结构转变的协调调控基因完整表达的自组织作用机制研究
Giovanna Zimatore,Masa Tsuchiya,Midori Hashimoto et al.
Giovanna Zimatore et al.
The human DNA molecule is a 2-m-long polymer collapsed into the micrometer space of the cell nucleus. This simple consideration rules out any "Maxwell demon"-like explanation of regulation in which a single regulatory molecule (e.g., a tran...
Extracting quantitative biological information from bright-field cell images using deep learning [0.03%]
基于深度学习从明场细胞图像中提取定量生物信息
Saga Helgadottir,Benjamin Midtvedt,Jesús Pineda et al.
Saga Helgadottir et al.
Quantitative analysis of cell structures is essential for biomedical and pharmaceutical research. The standard imaging approach relies on fluorescence microscopy, where cell structures of interest are labeled by chemical staining techniques...
Welcome to Biophysics Reviews, a big tent for the biophysics community [0.03%]
欢迎进入生物物理学评论，一个包容性的生物物理学术平台
Kevin Kit Parker,Luigi Longobardi,Amanda N Sulicz
Kevin Kit Parker
Selene De Martino,Paolo Antonio Netti
Selene De Martino
The ability to affect a wide range of biophysical properties through the use of light has led to the development of dynamic cell instructive materials. Using photoresponsive materials such as azopolymers, smart systems that use external, mi...