Bioactive hemostatic materials: a new strategy for promoting wound healing and tissue regeneration [0.03%]
生物活性止血材料：促进伤口愈合和组织再生的新策略
Zhengyuan Liu,Junnan Xu,Xing Wang
Zhengyuan Liu
Wound healing remains a critical global healthcare challenge, with an annual treatment cost exceeding $50 billion worldwide. Over the past decade, significant advances in wound care have focused on developing sophisticated biomaterials that...
ATP11B Modulates Microglial Lipid Metabolism and Alleviates Alzheimer's Disease Pathology [0.03%]
ATP11B调节小胶质细胞的脂质代谢并缓解阿尔茨海默病病理变化
Yuchen Zhang,Shibo Zhang,Xuyu Zhao et al.
Yuchen Zhang et al.
Abnormal lipid metabolism in microglia leads to the formation of pathological lipid droplets (LDs), a phenomenon also observed in neurodegenerative diseases such as Alzheimer's disease (AD). The abnormal accumulation of LDs disrupts normal ...
Integrated Analysis of the Anoikis-Related Signature Identifies Rac Family Small GTPase 3 as a Novel Tumor-Promoter Gene in Hepatocellular Carcinoma [0.03%]
综合性分析与脱落细胞死亡相关的基因特征鉴定出了Rac家族小GTP酶3是 hepatocellular carcinoma 中新型的肿瘤促进基因
Dong Wu,Ze-Kun Liu,Ying Sun et al.
Dong Wu et al.
Anoikis resistance in hepatocellular carcinoma (HCC) cells boosts survival and metastasis. This study aimed to establish an anoikis-related genes (ARGs)-based model for predicting HCC patients' outcomes and investigate the clinicopathologic...
Rational Design, Synthesis, and Biological Assessment of Potential Indole-Capped HDAC6 Inhibitors for Gastric Cancer Suppression [0.03%]
潜在的吲哚封端HDAC6抑制剂的理性设计、合成及生物活性评价用于胃癌治疗
Ya Gao,Hai-Qian Nie,Hong-Min Liu et al.
Ya Gao et al.
Subsequent Survival and Loss of Lifetime for Patients With Progression-Free 24 Months After Treatment in Nasopharyngeal Carcinoma: A Comprehensive Nationwide Population-Based Analysis [0.03%]
鼻咽癌治疗后24个月无进展患者的后续生存率及生命年限损失：一项全国性基于人群的综合分析
Yang Liu,Yaqian Han,Mei Feng et al.
Yang Liu et al.
Currently, there is little evidence supporting the use of early endpoints to assess primary treatment outcomes in nasopharyngeal carcinoma (NPC). We aim to explore the relationship between 24-month progression-free survival (PFS24) and subs...
Mitigating Early Phosphatidylserine Exposure in a Tmem30a-Dependent Way Ameliorates Neuronal Damages After Ischemic Stroke [0.03%]
以Tmem30a依赖性方式缓解早期卵磷脂酰丝氨酸暴露可减轻缺血性脑卒中后的神经元损伤
Chuanjie Wu,Jiaqi Guo,Yunxia Duan et al.
Chuanjie Wu et al.
Phosphatidylserine (PS) exposes to the outer plasma membrane after a pathological insult (e.g., stroke) but not under normal conditions whereby PS remains within the inner plasma membrane. However, the reversibility and translational potent...
Swimming Exercise Pretreatment Attenuates Postoperative Delirium-Like Behavior in Type 2 Diabetic Rats by Enhancing Mitochondrial Biogenesis Through Activation of SIRT2 Deacetylation [0.03%]
游泳锻炼通过激活SIRT2去乙酰化作用促进线粒体生物合成从而减轻2型糖尿病大鼠术后类似痴呆的行为反应
Kaixi Liu,Lei Chen,Xinning Mi et al.
Kaixi Liu et al.
Postoperative delirium (POD) is a common postsurgical complication that seriously affects patients' prognosis and imposes a heavy burden on families and society. Type 2 diabetes mellitus (T2DM) is a major risk factor for POD. The susceptibi...
A Single-Nucleus Transcriptomic Atlas Reveals Cellular and Genetic Characteristics of Alzheimer's-Like Pathology in Aging Tree Shrews [0.03%]
单核转录组图谱揭示了树鼩在衰老过程中类似阿尔茨海默病病理的细胞和遗传特征
Liu-Lin Xiong,Rong He,Ruo-Lan Du et al.
Liu-Lin Xiong et al.
The lack of natural aging-inducing Alzheimer's disease (AD) model presents a significant gap in the current preclinical research. Here, we identified a unique cohort of 10 naturally aging tree shrews (TSs) displaying distinct Alzheimer's-li...
Erratum: RETRACTION: ENKUR Recruits FBXW7 to Ubiquitinate and Degrade MYH9 and Further Suppress MYH9-Induced Deubiquitination of β-Catenin to Block Gastric Cancer Metastasis [0.03%]
撤稿声明：ENKUR 招募 FBXW7 以泛素化和降解MYH9 并进一步阻断胃癌转移抑制由 MYH9 诱导的β-连环蛋白的去泛素化
[This corrects the article DOI: 10.1002/mco2.185.]. © 2025 The Author(s). MedComm published by Sichuan International Medical Exchange & Promotion Associ...
Published Erratum
MedComm. 2025 Mar 11;6(3):e70160. DOI:10.1002/mco2.70160 2025
Bing Zhong,Jintao Du,Feng Liu et al.
Bing Zhong et al.
Yes-associated protein (YAP) plays a central role in the Hippo pathway, primarily governing cell proliferation, differentiation, and apoptosis. Its significance extends to tumorigenesis and inflammatory conditions, impacting disease initiat...