Michelle A Erickson,Morten S Nielsen
Michelle A Erickson
High-throughput drug screening to investigate blood-brain barrier permeability in vitro with a focus on breast cancer chemotherapeutic agents [0.03%]
一种高通量药物筛选方法 用于体外研究血脑屏障的渗透性 研究重点是乳腺癌化疗药物
Carolin J Curtaz,Sophia Wucherpfennig,Emad Al-Masnaea et al.
Carolin J Curtaz et al.
Therapy of cerebral diseases such as brain metastatic breast cancer is still challenging. Due to the blood-brain barrier (BBB), a tight barrier that protects the brain and prevents the passage of many drugs, therapeutically sufficient drug ...
Glucagon-like peptide-1 receptor agonists for treatment of diabetes and obesity: advantage of oral delivery [0.03%]
口服胰高糖素样肽-1受体激动剂治疗糖尿病和肥胖的优势
R R C New,M Bogus,G N Travers et al.
R R C New et al.
GLP-1 receptor agonists ((GLP-1 RAs) are currently receiving a lot of attention because of their impact in diabetes, weight loss and other areas. While GLP-1 RAs in injectable form are highly efficacious, further work is required to develop...
Future theranostic strategies: emerging ovarian cancer biomarkers to bridge the gap between diagnosis and treatment [0.03%]
未来诊疗策略：衔接卵巢癌诊断与治疗的生物标志物新进展
Weranga Rajapaksha,Riya Khetan,Ian R D Johnson et al.
Weranga Rajapaksha et al.
Ovarian cancers are a complex and heterogenic group of malignancies that are difficult to detect, diagnose and treat. Fortunately, considerable knowledge of ovarian cancer specific biomarkers has been generated, that is pertinent to the dev...
Italo Rodrigo Calori,Dimitrios A Lamprou
Italo Rodrigo Calori
Core-shell 3D printed biodegradable calcium phosphate cement-Alginate scaffolds for possible bone regeneration applications [0.03%]
用于可能的骨再生应用的芯-壳3D打印可降解磷酸钙水泥-藻酸盐支架
Clara Schweiker,Sergej Zankovic,Anna Baghnavi et al.
Clara Schweiker et al.
The core/shell 3D printing process using CPC and alginate is intended to create biodegradable scaffolds that have a similar stability to bone tissue and also offer sufficient and continuous antibiotic release. In this way, a patient-specifi...
Strategies and delivery systems for cell-based therapy in autoimmunity [0.03%]
自身免疫性疾病细胞疗法的治疗策略和递送系统
Matteo Puccetti,Claudio Costantini,Aurélie Schoubben et al.
Matteo Puccetti et al.
This review article explores the potential of engineering antigen-presenting cells (APCs) for the immunotherapy of autoimmune diseases. It discusses various strategies for modifying APCs to induce antigen-specific tolerance, thereby mitigat...
Szilvia Veszelka,Malgorzata Burek,Sarah Ann Thomas
Szilvia Veszelka
Targeting aerosol delivery to regions of nasal-associated lymphoid tissue (NALT) in three dimensional models of human intranasal airways using the BiVax intranasal atomizer [0.03%]
采用BiVax鼻吸入雾化器在人类鼻呼吸道三维模型中针对鼻相关淋巴组织(NALT)区域给药
Beth L Laube,Jana Kesavan,Gonçalo Farias et al.
Beth L Laube et al.
Introduction: Well-organized nasal-associated lymphoid tissue (NALT) has been identified in the pharyngeal and tubal tonsils of both adults and children, and diffuse NALT has been identified in the superior, middle and in...
SpheroMold: modernizing the hanging drop method for spheroid culture [0.03%]
改良悬挂滴培养法的球体培养模具(SpheroMold)
Ana Paula Pereira Guimaraes,Italo Rodrigo Calori,Hong Bi et al.
Ana Paula Pereira Guimaraes et al.
The hanging drop method is a cost-effective approach for 3D spheroid culture. However, obtaining numerous spheroids in a limited area becomes challenging due to the risk of droplet coalescence, primarly during Petri dish handling. In this s...