Nanoencapsulation of morin hydrate with BSA for sustained drug release in colorectal carcinoma cells: experimental and computational approach [0.03%]
实验与计算结合的方法制备包载杨梅素的纳米粒并评价其在结直肠癌细胞中持续释放的效果
Sanju Kumari Singh,Amit Kumar Srivastav,Sunaina Chaurasiya et al.
Sanju Kumari Singh et al.
Colorectal cancer is among the most redundant cancer of the gastrointestinal tract, with its burden expected to rise 60% by 2030. Morin hydrate (MH) is a bioflavonoid with anticancer attributes. However, the implementation of MH is limited ...
The stealth effect from a medicinal chemist perspective: definition and updates [0.03%]
从药物化学的角度来看隐身效应的定义和更新
Domenico Fuoco
Domenico Fuoco
In recent years, there has been a significant increase in literature on emerging nanotechnologies, including nanoparticles, nanorobots, and exosomes, for various therapeutic applications. Additionally, politically driven research initiative...
Synergistic mechanotherapy and sonopermeation guided by mathematical modeling for solid tumor treatment [0.03%]
基于数学建模的协同力学治疗与声学穿孔介导的实体瘤治疗
Marina Koutsi,Triantafyllos Stylianopoulos,Fotios Mpekris
Marina Koutsi
The progression of tumors and their response to treatment are significantly influenced by the presence of elevated mechanical solid stress. This solid stress compresses intratumoral blood vessels, leading to reduced blood flow (hypoperfusio...
Gene hydrogel platforms for targeted skin therapy: bridging hereditary disorders, chronic wounds, and immune related skin diseases [0.03%]
用于皮肤治疗的基因水凝胶平台：遗传病、慢性伤口和免疫相关皮肤病之间的桥梁疗法
Liangtao Li
Liangtao Li
Gene therapy, a pivotal cornerstone in biomedical research, has emerged as a transformative approach for addressing a wide spectrum of dermatologic conditions, including hereditary disorders, chronic wounds, and immune related skin diseases...
Corrigendum: Core-shell 3D printed biodegradable calcium phosphate cement - Alginate scaffolds for possible bone regeneration applications [0.03%]
有关可降解的钙磷水泥-海藻酸盐骨支架3D打印核心-壳结构的更正公告
Clara Schweiker,Sergej Zankovic,Anna Baghnavi et al.
Clara Schweiker et al.
[This corrects the article DOI: 10.3389/fddev.2024.1407304.]. Keywords: 3D printing; CPC; alginate; bone reg...
Published Erratum
Frontiers in drug delivery. 2024 Jul 18:4:1452132. DOI:10.3389/fddev.2024.1452132 2024
Choice of adjuvant and antigen composition alters the immunogenic profile of a SARS-CoV-2 subunit vaccine [0.03%]
佐剂和抗原组成的选择改变了SARS-CoV-2亚单位疫苗的免疫原性特征
William R Lykins,Jeroen Pollet,Jessica A White et al.
William R Lykins et al.
Introduction: Since their introduction, adjuvanted recombinant subunit vaccines against COVID-19 have played a pivotal role in protecting global populations. Optimizing the immune response's quality, amplitude, and durability to these vacci...
3D-printed weight holders design and testing in mouse models of spinal cord injury [0.03%]
脊髓损伤小鼠模型中3D打印重量支撑架的设计和测试
Sara De Vincentiis,Francesca Merighi,Peter Blümler et al.
Sara De Vincentiis et al.
This paper details the comprehensive design and prototyping of a 3D-printed wearable device tailored for mouse models which addresses the need for non-invasive applications in spinal cord studies and therapeutic treatments. Our work was pro...
Single cell phototransfection of mRNAs encoding SARS-CoV2 spike and nucleocapsid into human astrocytes results in RNA dependent translation interference [0.03%]
单细胞光转染SARS-CoV-2刺突和核衣壳mRNA进入人类星形胶质细胞导致RNA依赖性翻译干扰
Hyun-Bum Kim,Quentin Brosseau,Julia Radzio et al.
Hyun-Bum Kim et al.
Multi-RNA co-transfection is starting to be employed to stimulate immune responses to SARS-CoV-2 viral infection. While there are good reasons to utilize such an approach, there is little background on whether there are synergistic RNA-depe...
Poly(2-methyl-2-oxazoline) as a polyethylene glycol alternative for lipid nanoparticle formulation [0.03%]
聚（2-甲基-2-恶唑啉）作为脂质纳米颗粒配方中聚乙二醇的替代品
Dwain George van Zyl,Livia Palmerston Mendes,Raphaela Patricia Semper et al.
Dwain George van Zyl et al.
Lipid nanoparticles (LNPs) have emerged as the platform of choice for mRNA delivery. Polyethylene glycol (PEG) is considered a key component of currently approved LNP-based delivery systems as it ensures particle stability and shapes variou...
Corrigendum: Preliminary results on novel adjuvant combinations suggest enhancement immunogenicity of whole inactivated pandemic influenza vaccines [0.03%]
简讯：新型佐剂组合的初步结果表明，佐剂型全病毒甲型H1N1流感疫苗具有增强的免疫原性
Allegra Peletta,Aurélie Marmy,Samo Guzelj et al.
Allegra Peletta et al.
[This corrects the article DOI: 10.3389/fddev.2024.1382266.]. Keywords: NOD2 agonists; adjuvant; formulation...
Published Erratum
Frontiers in drug delivery. 2024 Dec 16:4:1519969. DOI:10.3389/fddev.2024.1519969 2024