Protein carbamylation and proteomics: from artifacts to elucidation of biological functions [0.03%]
蛋白质碳酰化与蛋白质组学：从技术干扰到阐明生物功能
Youngki You,Gina Many,Ernesto S Nakayasu
Youngki You
Lysine carbamylation is a non-enzymatic protein post-translational modification (PTM) that plays important roles in regulating enzymatic activity and the pathogenesis of diseases such as atherosclerosis, rheumatoid arthritis, and uremia. Th...
Toward the analysis of functional proteoforms using mass spectrometry-based stability proteomics [0.03%]
基于质谱的稳定性蛋白质组学在功能性蛋白质分析中的应用展望
Ji Kang,Meena Seshadri,Kellye A Cupp-Sutton et al.
Ji Kang et al.
Functional proteomics aims to elucidate biological functions, mechanisms, and pathways of proteins and proteoforms at the molecular level to examine complex cellular systems and disease states. A series of stability proteomics methods have ...
Direct analysis of tobacco specific nitrosamines in tobacco products using a molecularly imprinted polymer-packed column [0.03%]
使用分子印迹聚合物填充柱直接分析烟草制品中的烟草特有亚硝胺
Haley A Mulder,Justin L Poklis,Adam C Pearcy et al.
Haley A Mulder et al.
Tobacco specific nitrosamines (TSNAs) are highly carcinogenic by-products in tobacco samples, and their presence is regulated by the Food and Drug Administration. Molecularly imprinted polymers (MIPs) are synthetic polymers that have been "...
Hydrogen Deuterium Exchange and other Mass Spectrometry-based Approaches for Epitope Mapping [0.03%]
氢氘交换及其他基于质谱的表位测绘方法
Prashant N Jethva,Michael L Gross
Prashant N Jethva
Antigen-antibody interactions are a fundamental subset of protein-protein interactions responsible for the "survival of the fittest". Determining the interacting interface of the antigen, called an epitope, and that on the antibody, called ...
Perspective on the potential of tandem-ion mobility /mass spectrometry methods for structural proteomics applications [0.03%]
串联离子淌度/质谱方法在蛋白质结构组学应用中的潜力展望
Tyler C Cropley,Mengqi Chai,Fanny C Liu et al.
Tyler C Cropley et al.
Cellular processes are usually carried out collectively by the entirety of all proteins present in a biological cell, i.e. the proteome. Mass spectrometry-based methods have proven particularly successful in identifying and quantifying the ...