A short-lived fish with long-lasting effects: hallmarks of aging in Nothobranchius furzeri [0.03%]
短命鱼的长寿效应——Nothobranchius furzeri 的衰老特征
Oksana Savel,Julien Lehmann,Yusuf Kaan Poyraz et al.
Oksana Savel et al.
Our world is facing a global aging crisis with an increasing number of people living longer in poor health, as indicated by a gap between lifespan and healthspan. It is necessary to improve our knowledge of the biomolecular and cellular pat...
Sex differences in APOE- and PICALM-related cognitive profiles in healthy middle-aged adults [0.03%]
APOE和PICALM相关认知谱系的性别差异：一项针对健康中年人的研究
Adam Bednorz,Paulina Trybek,Minh Tuan Hoang et al.
Adam Bednorz et al.
Introduction: The APOE ε 4 and PICALM GG genotypes are strong genetic risk factors for Alzheimer's disease. This study aimed to identify cognitive subgroups using unsupervised machine learning and to investigate the...
Editorial: Immune senescence: a key driver of aging and age-related disorders [0.03%]
述评：免疫衰老：衰老及相关疾病的始动因素
Jing Luan,Bryan Wu,Xingchun Gao
Jing Luan
RNA transcripts in salivary extracellular vesicle cargo isolated from aged populations [0.03%]
来自老龄人群唾液外泌体中的RNA转录物
Sicheng Wen,Chang Yu,Maxfield M G Kelsey et al.
Sicheng Wen et al.
Introduction: Human saliva contains numerous factors, including DNA, RNA, and protein, that may reflect the health status of the individual. Many of these factors are contained within extracellular vesicles (EVs). The con...
Cellular senescence in age-related cardiovascular disease: past and future [0.03%]
细胞衰老与年龄相关心血管疾病：过去和未来
Xiang Wu,Qingyu Zhou,Yingying Huang et al.
Xiang Wu et al.
Cellular senescence is a distinct and definable biological state characterized by irreversible cell cycle arrest, accompanied by the activation of the DNA damage response (DDR), telomere shortening, the senescence-associated secretory pheno...
The effect of phenotypic aging on the relationship between cancer history and mortality in US adults [0.03%]
表型衰老对癌症史与美国成年人死亡率之间关系的影响
Meng-Hua Tao,Chun-Hui Lin,Shu-Chun Chuang et al.
Meng-Hua Tao et al.
Cancer survivors may have an accelerated biological aging process compared to cancer-free individuals. In this study, we aimed to investigate associations between clinical measures of biological aging and mortality (all-cause, cancer, and c...
Data-driven frailty and reserve phenotypes in older outpatients: a cluster analysis of complementary geriatric assessment [0.03%]
数据驱动的虚弱和储备表型在老年门诊患者中的群集分析：综合老年评估的补充性研究
Maristella Belfiori,Francesco Salis,Benedetta Puxeddu et al.
Maristella Belfiori et al.
Background: The progressive aging of the population represents a critical public health challenge. Within this context, the management of frailty has emerged as a central priority in geriatric care, with Comprehensive Ger...
New insights into the association between cardiometabolic index with metabolic profile, nutritional status, and inflammaging in older adults [0.03%]
心血管代谢指数与老年人代谢特征、营养状况及炎性衰老的关系的新认识
Sylvia Ramuth,Rafael Leite Carvalho,Rafael Zappitelli Moscogliato et al.
Sylvia Ramuth et al.
Introduction: Cardiometabolic index (CMI) has been highlighted as a useful tool for predicting cardiovascular and metabolic disease, but its association with systemic inflammatory status in the aged population is not yet ...
Nicholle Mae Amor Tan Maravilla,Myles Joshua Toledo Tan
Nicholle Mae Amor Tan Maravilla
The Timed Up and Go dual-task test's cognitive and motor outcomes show promising test-retest reliability in older adults with perceived memory impairment [0.03%]
时立走双任务测试在老年人群中具有良好的测评信度：尤其是那些有记忆力下降主诉的老年人群
Niklas Löfgren,Vilmantas Giedraitis,Kjartan Halvorsen et al.
Niklas Löfgren et al.
Background: It is of utmost importance to identify older adults at risk of cognitive impairment at the earliest possible stage. Previous research supports the potential of investigating step parameters and turn duration d...