Advances in anti-aging Drug research leveraging multi-omics and artificial intelligence [0.03%]
利用多组学和人工智能的抗衰老药物研究进展
Lijuan Gao,Yongsheng Qin,Yudai Xu et al.
Lijuan Gao et al.
The intensifying global population aging has rendered the development of anti-aging drugs a core challenge in the life sciences domain. Traditional models struggle to address the systemic and networked nature of aging. Multi-omics technolog...
Loneliness in older women: a multidimensional population-based study of social, health, and life-course factors [0.03%]
老年女性的孤独感：一项基于人口的社会、健康和生命周期因素的多维度研究
Esther Cabrera,Meritxell Puyané,Marc Terradellas et al.
Esther Cabrera et al.
Introduction: Loneliness in older women is a major public health concern in ageing societies and a key determinant of healthy ageing. Despite its multidimensional nature, evidence on the relative contribution of social, h...
Loneliness in older women: a multidimensional population-based study of social, health, and life-course factors [0.03%]
基于人口的女性孤独感因素的多维研究：社会、健康和生命周期因素
Esther Cabrera,Meritxell Puyané,Marc Terradellas et al.
Esther Cabrera et al.
Introduction: Loneliness in older women is a major public health concern in ageing societies and a key determinant of healthy ageing. Despite its multidimensional nature, evidence on the relative contribution of social, h...
Editorial: User-centered approaches for designing assistive technologies to support older adults [0.03%]
以用户为中心的设计辅助技术方法以支持老年人群
Samuel Olatunji,Neziha Akalin,Xiaomei Liu et al.
Samuel Olatunji et al.
Editorial: Machine learning-driven insights into cognitive aging and behavioral changes [0.03%]
机器学习驱动的认知衰老和行为改变的洞察力的观点文章
Jaiteg Singh,Amarjot Kaur Grewal,Sukhjit Singh Sehra et al.
Jaiteg Singh et al.
Mechanisms and management strategies for exacerbated bone loss following denosumab discontinuation [0.03%]
狄诺塞麦停药后的骨丢失加重的机制及管理策略
Jiancheng Yang,Ming Yang,Yuhong Zeng
Jiancheng Yang
Denosumab is a first-line therapy for osteoporosis, yet the rebound increase in bone turnover markers, rapid bone loss, and elevated fracture risk following its discontinuation have become major challenges in clinical management. This revie...
Loneliness and depression among older adults with cancer: an exploratory analysis of psychosocial constructs [0.03%]
老年人癌症患者的孤独和抑郁：心理社会因素的探索性分析
Addison Kitrel,Ellen Park,Elizabeth Schofield et al.
Addison Kitrel et al.
Introduction: Loneliness is a common and clinically significant concern among older adults with cancer (OACs; age ≥70), who often experience heightened psychological distress compounded by aging-related challenges. The c...
Association between frailty and incidence of AMD among middle-aged and older people: evidence from the UK Biobank [0.03%]
脆弱性与中老年人AMD发病率之间的关联：英国生物银行的证据
Hao Mou,Chang-Jun Zhang
Hao Mou
Background: To explore the association between age-related macular degeneration (AMD) and frailty and the link between frailty and neurological aging diseases in AMD patients. ...
Accelerated biological aging: the role of chronic inflammation, weathering and novel therapeutic strategies [0.03%]
加速的生物衰老：慢性炎症、老化磨损及新型治疗策略的作用
Frances M Marin-Maldonado,Mitzy J Santiago-Rosario,Wilfred Fonseca-Ferrer et al.
Frances M Marin-Maldonado et al.
Biological aging is a gradual, multisystem process characterized by progressive functional decline, diminished physiological resilience, and increased susceptibility to chronic diseases. Growing evidence suggests that persistent exposure to...
The negligible biological impact of reproductive history on aging: a high-resolution variance analysis [0.03%]
生育史对衰老的生物学影响微乎其微：高分辨率方差分析揭示了什么？
Marco Roccetti
Marco Roccetti
Modern epigenetics increasingly employs biological clocks to quantify the impact of women's reproductive history on aging, with a very recent study claiming that childbearing significantly decelerates biological senescence in women. This ar...