The Usefulness of Radiomics Methodology for Developing Descriptive and Prognostic Image-Based Phenotyping in the Aging Population: Results From a Small Feasibility Study [0.03%]
放射组学方法在基于影像的表型分型方面的应用价值：一项小型可行性研究的结果
Rebeca Mirón Mombiela,Consuelo Borrás
Rebeca Mirón Mombiela
Background: Radiomics is an emerging field that translates medical images into quantitative data to enable phenotypic profiling of human disease. In this retrospective study, we asked whether it is possible to use image-based phenotyping to...
Association of Vitamin K Insufficiency as Evaluated by Serum Undercarboxylated Osteocalcin With Frailty in Community-Dwelling Older Adults [0.03%]
血清未羧化骨钙素评估的维生素K缺乏与社区居住老年人衰弱的关系
Kotaro Azuma,Yosuke Osuka,Narumi Kojima et al.
Kotaro Azuma et al.
Frailty is the state of having a reduced ability to recover from stress. Intervention in frailty is important for fulfilling healthy longevity. Vitamin K is a fat-soluble vitamin contained in vegetables and fermented foods. Although vitamin...
Drosophila Lipase 3 Mediates the Metabolic Response to Starvation and Aging [0.03%]
ドロソフォラ・ライポーゼ3介导生物应对饥饿和衰老的代谢反应
Lea Hänschke,Christoph Heier,Santiago José Maya Palacios et al.
Lea Hänschke et al.
The human LIPA gene encodes for the enzyme lysosomal acid lipase, which hydrolyzes cholesteryl ester and triacylglycerol. Lysosomal acid lipase deficiency results in Wolman disease and cholesteryl ester storage disease. The Drosophila genom...
Brandt D Pence
Brandt D Pence
Aging increases susceptibility to and severity of a variety of chronic and infectious diseases. Underlying this is dysfunction of the immune system, including chronic increases in low-grade inflammation (inflammaging) and age-related immuno...
Prevalence and Correlates of Motoric Cognitive Risk Syndrome in Chinese Community-Dwelling Older Adults [0.03%]
中国社区老年人中运动认知风险综合征的流行病学特征及影响因素研究
Anying Bai,Weihao Xu,Zhanyi Lin
Anying Bai
Background: Motoric cognitive risk (MCR) syndrome is considered to be a pre-dementia syndrome. Although an increasing number of studies have begun to focus on this syndrome, few investigations have been launched in China. This study was per...
Low But Recoverable Markers of Humoral Immune Response to BNT162b2 in Elderly LTCF Residents Five to Seven Months After Two-Dose Vaccination [0.03%]
居民在老年护理机构接受两剂BNT162b2疫苗五至七个月后的体液免疫反应标志物较低但可恢复
Marla Delbrück,Sebastian Hoehl,Tuna Toptan et al.
Marla Delbrück et al.
The immune response is known to wane after vaccination with BNT162b2, but the role of age, morbidity and body composition is not well understood. We conducted a cross-sectional study in long-term care facilities (LTCFs) for the elderly. All...
The Dangers of Being Old in Rural Tanzania: A Call for Interventions for Strengthening Palliative Care in Low-Income Communities [0.03%]
坦桑尼亚农村老龄化带来的危险——加强低收入社区 palliative care 的对策呼吁
Kahabi Ganka Isangula
Kahabi Ganka Isangula
Sruti Shiva,Namakkal-Soorappan Rajasekaran,Bradford G Hill
Sruti Shiva
Dorota Skowronska-Krawczyk,Priyanka Narayan,Peter Tessarz
Dorota Skowronska-Krawczyk
Differential Effects of 2-Deoxyglucose and Glucose Deprivation on 4-Hydroxynonenal Dependent Mitochondrial Dysfunction in Primary Neurons [0.03%]
2-脱氧葡萄糖和葡萄糖剥夺对主要神经元中4-羟基壬烯醛依赖的线粒体功能障碍的不同影响
Matthew Dodson,Gloria A Benavides,Victor Darley-Usmar et al.
Matthew Dodson et al.
Mitochondrial dysfunction and metabolic decline are prevalent features of aging and age-related disorders, including neurodegeneration. Neurodegenerative diseases are associated with a progressive loss of metabolic homeostasis. This pathoge...