Raghu P Kataru,Hyeung Ju Park,Jinyeon Shin et al.
Raghu P Kataru et al.
Lymphatic structure and function play a critical role in fluid transport, antigen delivery, and immune homeostasis. A dysfunctional lymphatic system is associated with chronic low-grade inflammation of peripheral tissues, poor immune respon...
A Systematic Review of the Effects of Second-Eye Cataract Surgery on Motor Function [0.03%]
第二眼白内障手术对运动功能的影响的系统评价
William E A Sheppard,Dane McCarrick,Richard M Wilkie et al.
William E A Sheppard et al.
Cataract removal surgery is one of the most commonly performed surgical procedure in developed countries. The financial and staff resource cost that first-eye cataract surgery incurs, leads to restricted access to second-eye cataract surger...
Age and Sex Differences in Heart Failure With Preserved Ejection Fraction [0.03%]
射血分数保留的心力衰竭的年龄和性别差异
Kamil Aleksander Kobak,Weronika Zarzycka,Ying Ann Chiao
Kamil Aleksander Kobak
Heart failure with preserved ejection fraction (HFpEF) is a multi-organ disorder that represents about 50% of total heart failure (HF) cases and is the most common form of HF in the elderly. Because of its increasing prevalence caused by th...
Developments in Deep Brain Stimulators for Successful Aging Towards Smart Devices-An Overview [0.03%]
面向成功老龄的深部脑刺激器的发展走向智能设备-综述
Angelito A Silverio,Lean Angelo A Silverio
Angelito A Silverio
This work provides an overview of the present state-of-the-art in the development of deep brain Deep Brain Stimulation (DBS) and how such devices alleviate motor and cognitive disorders for a successful aging. This work reviews chronic dise...
A Randomized Controlled Clinical Trial in Healthy Older Adults to Determine Efficacy of Glycine and N-Acetylcysteine Supplementation on Glutathione Redox Status and Oxidative Damage [0.03%]
一项随机对照临床试验:在健康老年人中确定甘氨酸和N-乙酰半胱氨酸补充对谷胱甘肽氧化还原状态及氧化损伤的效果
Giulia Lizzo,Eugenia Migliavacca,Daniela Lamers et al.
Giulia Lizzo et al.
Glycine and cysteine are non-essential amino acids that are required to generate glutathione, an intracellular tripeptide that neutralizes reactive oxygen species and prevents tissue damage. During aging glutathione demand is thought to inc...
Johannes Leth Nielsen,Daniela Bakula,Morten Scheibye-Knudsen
Johannes Leth Nielsen
The risk of morbidity and mortality increases exponentially with age. Chronic inflammation, accumulation of DNA damage, dysfunctional mitochondria, and increased senescent cell load are factors contributing to this. Mechanistic investigatio...
The FGFR4 Homolog KIN-9 Regulates Lifespan and Stress Responses in Caenorhabditis elegans [0.03%]
FGFR4同源蛋白KIN-9通过调节秀丽隐杆线虫的寿命和应激反应发挥作用
Avijit Mallick,Leo Xu,Sakshi Mehta et al.
Avijit Mallick et al.
Fibroblast growth factor receptors (FGFRs) regulate diverse biological processes in eukaryotes. The nematode Caenorhabditis elegans is a good animal model for studying the roles of FGFR signaling and its mechanism of regulation. In this stu...
A Brief Report on Reviews of Existing Creative Art-Based Interventions in Dementia Care From 2010-2020 [0.03%]
2010至2020年基于创意艺术的痴呆症护理干预措施回顾简报
Irfan Manji,Pascal Fallavollita
Irfan Manji
The following brief report provides an overview of previously published reviews in the context of creative arts-based interventions for persons with dementia. A total of 22 review articles were identified and summarized. Next steps are sugg...
Kavya Leo Vakkayil,Thorsten Hoppe
Kavya Leo Vakkayil
Temperature is an important environmental condition that determines the physiology and behavior of all organisms. Animals use different response strategies to adapt and survive fluctuations in ambient temperature. The hermaphrodite Caenorha...
Recent Advances on Drug Development and Emerging Therapeutic Agents Through Targeting Cellular Homeostasis for Ageing and Cardiovascular Disease [0.03%]
通过靶向细胞稳态防治心血管疾病和衰老的药物研发进展及新兴治疗剂
Tayyiba Azam,Hongyuan Zhang,Fangchao Zhou et al.
Tayyiba Azam et al.
Ageing is a progressive physiological process mediated by changes in biological pathways, resulting in a decline in tissue and cellular function. It is a driving factor in numerous age-related diseases including cardiovascular diseases (CVD...