Healthy Aging: Comparative Analysis of Local Perception and Diet in Two Health Districts of Côte d'Ivoire and Japan [0.03%]
健康老龄化：象牙海岸和日本两个卫生区的当地认知与饮食比较分析
B Bonfoh,B V Koné,Y D Koffi et al.
B Bonfoh et al.
Context: Good health and longevity depend on dynamic interactions between biological, social, psychological, and environmental factors. Aging is globally a big challenge, particularly with the demographic transition, including population gr...
Yasmine J Liu,Rebecca L McIntyre,Georges E Janssens
Yasmine J Liu
Public attention and interest for longevity interventions are growing. These can include dietary interventions such as intermittent fasting, physical interventions such as various exercise regimens, or through supplementation of nutraceutic...
Manish K Gupta,Puneet Kaur Randhawa,Michal M Masternak
Manish K Gupta
Cardiovascular disorder is the major health burden and cause of death among individuals worldwide. As the cardiomyocytes lack the ability for self-renewal, it is utmost necessary to surveil the protein quality in the cells. The Bcl-2 associ...
Progerin-Induced Impairment in Wound Healing and Proliferation in Vascular Endothelial Cells [0.03%]
端粒酶PROGERIN诱导血管内皮细胞损伤修复和增殖能力下降
Yizhi Jiang,Julie Y Ji
Yizhi Jiang
Progerin as a mutated isoform of lamin A protein was first known to induce premature atherosclerosis progression in patients with Hutchinson-Gilford progeria syndrome (HGPS), and its role in provoking an inflammatory response in vascular ce...
Inhibiting BDNF Signaling Upregulates Hippocampal H3K9me3 in a Manner Dependent On In Vitro Aging and Oxidative Stress [0.03%]
BDNF信号抑制以依赖于体外衰老和氧化应激的方式上调海马H3K9me3标记
Andra Ionescu-Tucker,Liqi Tong,Nicole C Berchtold et al.
Andra Ionescu-Tucker et al.
Histone modifications are key contributors to the cognitive decline that occurs in aging and Alzheimer's disease. Our lab has previously shown that elevated H3K9me3 in aged mice is correlated with synaptic loss, cognitive impairment and a r...
The Importance of Motivation to Older Adult Physical and Cognitive Exercise Program Development, Initiation, and Adherence [0.03%]
动机在老年人身体和认知锻炼项目开发、启动和坚持中的重要性
Therese M O&#x;Neil-Pirozzi,Gabriele Cattaneo,Javier Solana-Sánchez et al.
Therese M O&#x;Neil-Pirozzi et al.
Brain health is essential to successful aging, and exercise is essential to brain health. Evidence supports the benefits of regular physical and cognitive exercise in preventing or delaying progressin of mild cognitive impairment and dement...
Translation of Cellular Senescence to Novel Therapeutics: Insights From Alternative Tools and Models [0.03%]
细胞衰老向新型药物的转化：来自替代工具和模型的启示
Nurcan Inci,Dilanur Kamali,Erdogan Oguzhan Akyildiz et al.
Nurcan Inci et al.
Increasing chronological age is the greatest risk factor for human diseases. Cellular senescence (CS), which is characterized by permanent cell-cycle arrest, has recently emerged as a fundamental mechanism in developing aging-related pathol...
Eduardo L Abreu,Amy Vance,An-Lin Cheng et al.
Eduardo L Abreu et al.
Exercise is an essential component of any good health style, being particularly important for older adults to counteract the effects of aging, including sarcopenia and osteoporosis, which can result in lower fall probability. Exercise progr...
Kyoo-A Lee,Rafael R Flores,In Hwa Jang et al.
Kyoo-A Lee et al.
With aging, there is increased dysfunction of both innate and adaptive immune responses, which contributes to impaired immune responses to pathogens and greater mortality and morbidity. This age-related immune dysfunction is defined in gene...
Consuelo Borrás,Laura Haynes,Jianhua Zhang
Consuelo Borrás