ET-1 as a Sex-Specific Mechanism Impacting Age-Related Changes in Vascular Function [0.03%]
ET-1作为影响血管功能衰老的性别特异性机制
Andrew V Kuczmarski,Laura M Welti,Kerrie L Moreau et al.
Andrew V Kuczmarski et al.
Aging is a primary risk factor for cardiovascular disease (CVD), which is the leading cause of death in developed countries. Globally, the population of adults over the age of 60 is expected to double by the year 2050. CVD prevalence and mo...
Corrigendum: Key Determinants of Cell-Mediated Immune Responses: A Randomized Trial of High Dose Vs. Standard Dose Split-Virus Influenza Vaccine in Older Adults [0.03%]
高剂量与标准剂量分割流感疫苗对老年人细胞介导的免疫反应的关键决定因素随机试验的勘误表
Chris P Verschoor,Laura Haynes,Graham Pawelec et al.
Chris P Verschoor et al.
[This corrects the article DOI: 10.3389/fragi.2021.649110.]. Keywords: cell-mediated immune responses; cytom...
Published Erratum
Frontiers in aging. 2021 Jun 25:2:718966. DOI:10.3389/fragi.2021.718966 2021
Oral-Gut-Brain Axis in Experimental Models of Periodontitis: Associating Gut Dysbiosis With Neurodegenerative Diseases [0.03%]
实验模型中的牙周炎的口-肠-脑轴：将肠道菌群失调与神经退行性疾病相关联
Luis Daniel Sansores-España,Samanta Melgar-Rodríguez,Katherine Olivares-Sagredo et al.
Luis Daniel Sansores-España et al.
Periodontitis is considered a non-communicable chronic disease caused by a dysbiotic microbiota, which generates a low-grade systemic inflammation that chronically damages the organism. Several studies have associated periodontitis with oth...
Prescription Medications and Co-Morbidities in Late Middle-Age are Associated with Greater Cognitive Declines: Results from WRAP [0.03%]
药物使用和共病与晚期中年认知衰退加剧有关——WRAP的结果
Lianlian Du,Rebecca Langhough Koscik,Nathaniel A Chin et al.
Lianlian Du et al.
The present study investigated: 1) sex differences in polypharmacy, comorbidities, self-rated current health (SRH), and cognitive performance, 2) associations between comorbidities, polypharmacy, SRH, and objective measures of health, and 3...
David Weinkove,Giulia Zavagno
David Weinkove
The increase in our molecular understanding of the biology of aging, coupled with a recent surge in investment, has led to the formation of several companies developing pharmaceuticals to slow aging. Research using the tiny nematode worm Ca...
Attiya A Abbas,Arne N Akbar
Attiya A Abbas
As people around the world continue to live longer, maintaining a good quality of life is of increasing importance. The COVID-19 pandemic revealed that the elderly are disproportionally vulnerable to infectious diseases and Immunosenescence...
Removal of p16 INK4 Expressing Cells in Late Life has Moderate Beneficial Effects on Skeletal Muscle Function in Male Mice [0.03%]
老年期清除p16INK4阳性细胞对雄性小鼠骨骼肌功能的有益影响较小
Steve D Guzman,Jennifer Judge,Shahjahan M Shigdar et al.
Steve D Guzman et al.
Aging results in the progressive accumulation of senescent cells in tissues that display loss of proliferative capacity and acquire a senescence-associated secretory phenotype (SASP). The tumor suppressor, p16 INK4A , which slows the progre...
Integrative Role of Hyperbaric Oxygen Therapy on Healthspan, Age-Related Vascular Cognitive Impairment, and Dementia [0.03%]
高压氧治疗在健康寿命、与年龄相关的血管性认知障碍和痴呆中的整合作用
Priya Balasubramanian,Jordan Delfavero,Adam Nyul-Toth et al.
Priya Balasubramanian et al.
Growing life expectancy will contribute to the on-going shift towards a world population increasingly comprised of elderly individuals. This demographic shift is associated with a rising prevalence of age-related diseases, among all age-rel...
Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence [0.03%]
模式生物中的血管衰老：驱动雌雄血管老化的机制对比研究
Paula R Barros,Tiago J Costa,Eliana H Akamine et al.
Paula R Barros et al.
Increasing scientific interest has been directed to sex as a biological and decisive factor on several diseases. Several different mechanisms orchestrate vascular function, as well as vascular dysfunction in cardiovascular and metabolic dis...
Morgane Davezac,Melissa Buscato,Rana Zahreddine et al.
Morgane Davezac et al.
Cardiovascular diseases remain an age-related pathology in both men and women. These pathologies are 3-fold more frequent in men than in women before menopause, although this difference progressively decreases after menopause. The vasculopr...