Belay Tessema,Ulrich Sack,Zoya Serebrovska et al.
Belay Tessema et al.
The effects of short-term hyperoxia on age-related diseases and aging biomarkers have been reported in animal and human experiments using different protocols; however, the findings of the studies remain conflicting. In this systematic revie...
Recent Advances in Studying Age-Associated Lipids Alterations and Dietary Interventions in Mammals [0.03%]
近期关于哺乳动物年龄相关脂质变化及饮食干预的研究进展
Benedikt Gille,Christina E Galuska,Beate Fuchs et al.
Benedikt Gille et al.
Lipids are involved in a broad spectrum of canonical biological functions, from energy supply and storage by triacylglycerols to membrane formation by sphingolipids, phospholipids and glycolipids. Because of this wide range of functions, th...
Shengxin Li,Hyun-Eui Kim
Shengxin Li
Aging is a process leading to a progressive loss of physiological integrity and homeostasis, and a primary risk factor for many late-onset chronic diseases. The mechanisms underlying aging have long piqued the curiosity of scientists. Howev...
mTORC1 Crosstalk With Stress Granules in Aging and Age-Related Diseases [0.03%]
衰老及相关疾病中mTORC1与应激颗粒的互作关系
Marti Cadena Sandoval,Alexander Martin Heberle,Ulrike Rehbein et al.
Marti Cadena Sandoval et al.
The mechanistic target of rapamycin complex 1 (mTORC1) kinase is a master regulator of metabolism and aging. A complex signaling network converges on mTORC1 and integrates growth factor, nutrient and stress signals. Aging is a dynamic proce...
Efficacy of Tai Chi-Style Multi-Component Exercise on Frontal-Related Cognition and Physical Health in Elderly With Amnestic Mild Cognitive Impairment [0.03%]
太极拳多成分锻炼改善遗忘性轻度认知障碍老人额叶相关认知和身心健康的有效性：一项随机对照试验
Shao-Yun Yang,Hsuei-Chen Lee,Chih-Mao Huang et al.
Shao-Yun Yang et al.
Early prevention from accelerated neurocognitive declines with advanced aging and the delay of the onset of dementia have became paramount for the achievement of active aging. The present study examined whether the proposed non-pharmaceutic...
In vivo Pooled Screening: A Scalable Tool to Study the Complexity of Aging and Age-Related Disease [0.03%]
用于研究衰老和与年龄相关疾病的体内汇集筛选：一种可扩展工具
Martin Borch Jensen,Adam Marblestone
Martin Borch Jensen
Biological aging, and the diseases of aging, occur in a complex in vivo environment, driven by multiple interacting processes. A convergence of recently developed technologies has enabled in vivo pooled screening: direct administration of a...
Curiosity-Based Interventions Increase Everyday Functioning Score But Not Serum BDNF Levels in a Cohort of Healthy Older Adults [0.03%]
基于好奇心的干预可以改善健康老年人的日常生活功能评分但不能提高BDNF水平
Allison N Grossberg,Brianne M Bettcher,Kim A Gorgens et al.
Allison N Grossberg et al.
An enriched environment is effective in stimulating learning and memory in animal models as well as in humans. Environmental enrichment increases brain-derived neurotrophic factor (BDNF) in aged rats and reduces levels of Alzheimer-related ...
Consuelo Borrás
Consuelo Borrás
Patterns of Self-Care Behaviors and Their Influence on Maintaining Independence: The National Health and Aging Trends Study [0.03%]
自我保健行为模式及其对维持独立生活的影响：来自《美国国家健康与老龄化趋势研究》的数据分析
Thelma J Mielenz,Sneha Kannoth,Qian-Li Xue
Thelma J Mielenz
Importance: Few studies have addressed the combined effects of health-promoting and self-care behaviors among older adults. Thus, new research is needed to assess the potential for behavior change to prolong independence in later life. Obje...
From Autonomy to Integration, From Integration to Dynamically Balanced Integrated Co-existence: Non-aging as the Third Stage of Development [0.03%]
从自主到融合再到动态均衡共存：不老作为发展的第三阶段
Lev Salnikov,Mamuka G Baramiya
Lev Salnikov
Reversible senescence at the cellular level emerged together with tissue specialization in Metazoans. However, this reversibility (ability to permanently rejuvenate) through recapitulation of early stages of development, was originally a pa...