Comparing arm to whole-body motor control disambiguates age-related deterioration from compensation [0.03%]
比较单纯手臂与全身运动控制，排除了由于代偿造成的年龄相关功能衰退的影响
Robin Mathieu,Florian Chambellant,Denis Barbusse et al.
Robin Mathieu et al.
Background: As the global population ages, it is crucial to understand sensorimotor compensation mechanisms. These mechanisms are thought to enable older adults to remain in good physical health, but despite important res...
Nutritional status associated with physical activity in active older adults in southern Ecuador [0.03%]
厄瓜多尔南部活跃老年人的营养状况与身体活动关系探讨
Lorena Encalada-Torres,Ivanna Buri-Encalada,Victoria Abril-Ulloa et al.
Lorena Encalada-Torres et al.
Introduction: The increase in the number of older adults at a global level is increasing the incidence of morbidity and mortality associated with lack of physical activity and malnutrition in this vulnerable group. The ob...
Ginsenoside Rg1 antagonizes diabetic osteoporosis by regulating ferroptosis via mitochondrial membrane potential in H-type vascular endothelial cells [0.03%]
人参皂苷Rg1通过调节H型血管内皮细胞线粒体膜电位介导的铁死亡拮抗糖尿病性骨质疏松症
Mi Chen,Hongxiang Zheng,Rui Bai et al.
Mi Chen et al.
Background: Endothelial dysfunction under high-glucose conditions is a key pathological process contributing to the development and progression of diabetic osteoporosis (DOP). High glucose-induced damage to H-type vascula...
Evaluation of bempedoic acid in elderly patients: real-world evidence from the REALIST study [0.03%]
REALIST研究的老年人用药评估：真实世界证据分析
Saverio Muscoli,Emanuele Di Marco,Fiorella Puttini et al.
Saverio Muscoli et al.
Statin intolerance and PCSK9 inhibitor reimbursement restrictions limit lipid-lowering options for elderly patients at high cardiovascular (CV) risk. Bempedoic acid (BA), an ATP-citrate lyase inhibitor, is a promising alternative. This stud...
First metagenomic analysis of age-associated changes in the gut microbiome among healthy Saudi adults: SAMS pilot study [0.03%]
沙特成人健康人群中首个关于肠道菌群随年龄变化的元基因组分析：SAMS初步研究
Roua Almatrafi,Abdulrahman Alasiri,Ghaida Almuneef et al.
Roua Almatrafi et al.
Introduction: The gut microbiome undergoes dynamic changes with aging across diverse healthy populations. However, data from Saudi Arabia remain limited. This pilot study investigated age-related variations in the gut mic...
Anshen Bunao syrup as a potential anti-aging agent: mechanistic insights and pharmacological evidence [0.03%]
安心补脑糖浆作为潜在的抗衰老剂：机制见解和药理证据
Yuanfang Sun,Qi Xia,Ruolan Wu et al.
Yuanfang Sun et al.
Background: Anshen Bunao Syrup (ABS) is a commonly used traditional Chinese patent medicine for insomnia and amnesia, and also has the potential to anti-aging but lacks scientific support of pharmacological and mechanism ...
Neurosenescence, inflammaging and neuroinflammation in neurodegenerative disorders [0.03%]
神经退行性疾病中的神经衰老、炎症和神经炎症
Duraisamy Kempuraj,Prathiv Raj Ramesh Babu,Nithura Jayakumar et al.
Duraisamy Kempuraj et al.
Senescence is the biological aging associated with the gradual deterioration of cells and functions of various organs over time. This irreversible process is caused by genetic, metabolic, and environmental factors, such as telomere shorteni...
Wnt16: a new potential therapeutic target for osteoporotic non-vertebral fracture treatment [0.03%]
Wnt16：治疗骨质疏松性非椎体骨折的新的潜在治疗靶点
Chen Tianpeng,Xia Qishui,Yang Fo et al.
Chen Tianpeng et al.
Osteoporotic non-vertebral fractures are a major clinical burden, with cortical bone impairment being a key pathogenic factor often overlooked in traditional treatments. This review aims to synthesize current evidence on the role of Wnt16 (...
Research hotspots and trends in intrinsic capacity of older people in the context of population aging based on CiteSpace [0.03%]
基于CiteSpace的背景下我国人口老龄化内在能力研究热点及趋势分析
Minhua Ren,Hongtao Guo,Ye Tian et al.
Minhua Ren et al.
Objective: To employ bibliometrics to identify the research hotspots and development trends of the intrinsic capacity of older people, thereby providing novel insights for future studies on the management of intrinsic cap...
SARC-T a new physical test for sarcopenia assessment with development, validation and physiological evaluation [0.03%]
SARC-T：一种新的体能测试方法用于评估肌少症的发展、验证和生理评价
Blanca Pedauyé-Rueda,José Luis Maté-Muñoz,Juan Hernández-Lougedo et al.
Blanca Pedauyé-Rueda et al.
Background: Sarcopenia is a disease characterized by the progressive loss of muscle mass and strength associated with aging. There are marked differences in sarcopenia prevalence depending on the diagnostic algorithm used...