CD21+CD11c+ B cells predicting handgrip strength decline in older adults [0.03%]
CD21+CD11c+ B细胞可预测老年人握力下降
Diego Mabe-Castro,Matías Mabe-Castro,Lindybeth Sarmiento Varón et al.
Diego Mabe-Castro et al.
Background: Preserving physical function is central to healthy aging, and declines in handgrip strength are strong predictors of frailty, disability, and mortality. Although immunosenescence has been implicated in age-rel...
An overview of current research on exercise interventions in aging and aging-related disease [0.03%]
运动干预与衰老及衰老相关疾病的当前研究综述
Arad Jain,Campbell Johnston,Yiyu Zhang et al.
Arad Jain et al.
Global declines in physical activity have contributed to an acceleration in immune aging, characterized by systemic inflammation (inflammaging) and impaired immune regulation (immunosenescence). This narrative review provides an overview of...
Tobacco, biological aging and epigenetic resilience: the Andorran paradox [0.03%]
烟草、生物衰老和表观遗传适应性：安道尔悖论
Pooja Reddy,Dhairya Nanavaty,Pradeepkumar Devarakonda et al.
Pooja Reddy et al.
Longevity is not solely determined by the absence of risk factors but often reflects the balance between harmful exposures and protective adaptations. We introduce the framework of epigenetic resilience as a counterbalancing mechanism by wh...
Synergistic effects of group-based exercise to reduce loneliness and social isolation and to prevent cognitive decline among older adults with cancer [0.03%]
基于团队的锻炼对老年癌症患者减少孤独感和社交孤立感及预防认知能力下降的协同作用
Heather J Leach,Jaclyn A Stephens,Diane K Ehlers
Heather J Leach
The growing population of older cancer survivors faces an elevated risk of accelerated cognitive decline due to the combined effects of aging and cancer-related cognitive impairment. Loneliness and social isolation have also been linked to ...
Ahalya Kanakan,Anup Singh,Sarita Kumari et al.
Ahalya Kanakan et al.
Chronic inflammation contributes to the pathogenesis of sarcopenia in older adults. This study aimed to evaluate the correlation between inflammatory biomarkers such as C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), interle...
Association of LDL protein cargo with segmental pulse wave velocity in older adults in the atherosclerosis risk in communities study [0.03%]
动脉粥样硬化社区研究中LDL蛋白货物与老年人节段脉搏波速度的相关性
Binchong An,Pamela L Lutsey,Michelle M Mielke et al.
Binchong An et al.
Background: Low-density lipoprotein cholesterol (LDL-C) is associated with brachial-ankle pulse wave velocity (baPWV). However, its relationship with femoral-ankle PWV (faPWV) or carotid-femoral PWV (cfPWV) is less consis...
Unseen and untreated: implementing sarcopenic obesity care in Nordic general practice [0.03%]
未被发现和治疗的 sarcopenic肥胖在北欧国家基层医疗中的实施状况
Fereshteh Baygi,Peter Haastrup,Sussi Friis Buhl et al.
Fereshteh Baygi et al.
Background: Sarcopenic obesity (SO) is defined as the coexistence of low muscle mass and excess adiposity. Despite growing international attention, SO remains under-researched and under-recognized in Nordic countries, par...
Racial disparities in pain and total knee arthroplasty across knee osteoarthritis phenotypes [0.03%]
不同膝骨关节炎表型的种族疼痛差异和全膝关节置换术
Ahmad Alkhatatbeh,Tariq Alkhatatbeh,Jiechen Chen et al.
Ahmad Alkhatatbeh et al.
Introduction: Knee osteoarthritis is heterogeneous in radiographic severity, pain, and multimorbidity, and racial disparities in pain and knee replacement are documented. We derived knee osteoarthritis phenotypes from ele...
Loneliness and cognitive aging: a brain-heart axis perspective on a modifiable risk [0.03%]
孤独与认知老化：从可改变风险的角度看待脑-心轴线关系
Alison Warren
Alison Warren
Loneliness, the subjective perception of inadequate social connection, is increasingly recognized as a significant and modifiable determinant of health with implications extending beyond psychosocial well-being to cardiovascular and cogniti...
Impact of pulsed electromagnetic fields on intervertebral disc degeneration: a systematic review of preclinical and clinical evidence [0.03%]
脉冲电磁场对椎间盘退变的影响：系统综述证据
Francesca Veronesi,Francesca Salamanna,Lucia Martini et al.
Francesca Veronesi et al.
Introduction: Low back pain (LBP) is a leading cause of disability worldwide, with intervertebral disc degeneration (IDD) as a major contributor. IDD is strongly associated with aging and is characterized by cellular sene...