Physiological amplitude: a systems-level framework for adaptive capacity in aging and metabolism [0.03%]
生理振幅：衰老和代谢适应能力的系统水平框架
Grazyna Sepczynska
Grazyna Sepczynska
Background: Aging is characterized by progressive loss of physiological complexity, inter-system coordination, and adaptive capacity. While mitochondrial dysfunction, metabolic inflexibility, impaired stress responses, an...
Gut microbiota-epigenetic interactions in systemic aging: mechanistic drivers for endocrine and reproductive network remodeling and therapeutic modulation [0.03%]
肠道微生物组-表观遗传互作与系统性衰老：内分泌及生殖网络重塑的机制驱动因子和治疗干预方式
Christopher Birigwa,Qiang Tong,Bing Qu et al.
Christopher Birigwa et al.
Researchers now see aging as a process shaped by the interactions among metabolism, epigenetics, and hormones. Recent studies suggest that gut microbes play an important role in this system by making metabolites that can affect gene express...
Aging strong: an N = 1 mixed-methods study of long-term supervised high-intensity resistance training in a 71-year-old woman [0.03%]
高强度抗阻训练使七十一岁女性获益：一名受试者长达五年的混合方法研究
Itai Har-Nir,Noam Manor,Jana Pelclova
Itai Har-Nir
Older adults who engage in long-term, supervised high-intensity resistance training (HIRT) may preserve musculoskeletal function, independence, and psychological resources beyond typical age-related expectations. This N = 1 mixed-methods st...
Strategies of oral hygiene care for healthy aging: insights from elderly care in Taiwan [0.03%]
口腔卫生保健的策略与健康老龄化：台湾养老机构的新视角
Ming-Kuo Chen,Patrick Pang,Yi-Huang Shih et al.
Ming-Kuo Chen et al.
Sex-specific differences in vascular circulation and metabolic regulation associated with aging and cardiovascular health problems [0.03%]
性别特异的与衰老和心血管健康问题相关的血管循环和代谢调节差异
Andrzej Marcinek,Joanna Katarzynska,Jerzy Gebicki
Andrzej Marcinek
The Flow Mediated Skin Fluorescence-Post-Occlusive Reactive Hyperemia (FMSF-PORH) technique proves that the skin can serve as an easily accessible and sensitive model for monitoring systemic redox changes in the NADH/NAD+ balance. The three...
Cognitive decline, and quality of life: evidence from community-dwelling older adults in the United Arab Emirates [0.03%]
认知衰退与生活质量：来自阿拉伯联合酋长国社区老年人的证据
Wegdan Bani Issa,Dana N Abdelrahim,Hadia Radwan et al.
Wegdan Bani Issa et al.
Background: Cognitive function and quality of life (QoL) are closely linked in older adults, with accumulating evidence suggesting that cognitive performance is an important determinant of overall perceived QoL in older a...
Physical exercise therapy as an anti-aging strategy for osteosarcopenia: a narrative review [0.03%]
运动疗法作为防治骨肌衰老的策略：综述文章
Ting Ting Liu,Pengwei Zhang,Wan Tao Dong et al.
Ting Ting Liu et al.
With global population aging accelerating, osteosarcopenia-the coexistence of sarcopenia and osteoporosis-has become a critical health challenge leading to frailty, falls, and disability in the elderly. This syndrome is closely linked to ch...
The lifespan and healthspan extending effects of ellagic acid in Caenorhabditis elegans require an intact insulin/IGF-1 signaling pathway [0.03%]
ellagic酸通过完整的胰岛素/IGF-1信号传导途径延长线虫寿命和健康寿命
Lipeng Xu,Jinze Li,Anran Li et al.
Lipeng Xu et al.
Introduction: Ellagic acid (EA) is a naturally occurring polyphenolic antioxidant speculated to influence aging, but its precise biological mechanisms remain poorly understood. ...
Underuse of osteoporosis treatments before and after hip fracture: longitudinal findings from the Gruppo Italiano di Ortogeriatria (GIOG 2.0) study [0.03%]
来自Gruppo Italiano di Ortogeriatria（GIOG 2.0）研究的纵向发现：髋部骨折前后的骨质疏松症治疗不足
Maria Cristina Ferrara,Wenxiang Guo,Eleonora Cucini et al.
Maria Cristina Ferrara et al.
Background: Osteoporosis is a major cause of fragility fractures, with hip fracture (HF) representing the most severe complication in older adults. However, national data on osteoporosis treatment use before and after hip...
Measurement properties of the SARC-T: test-retest reliability, agreement and minimal detectable change in older adults with sarcopenia [0.03%]
SARC-T的测量属性：老年人肌少症患者重测信度、一致性以及最小可检测变化量的评估
Blanca Pedauyé-Rueda,José Luis Maté-Muñoz,Juan Hernández-Lougedo et al.
Blanca Pedauyé-Rueda et al.
Background: The Sarcopenia Optoelectronic Chair-Rise Velocity Test (SARC-T) has been proposed as an instrumented chair-rise measure related to physical function in sarcopenia; however, its test-retest measurement properti...