Construction of EpCAM overexpression and knockdown vectors and their implications in colorectal cancer research [0.03%]
CEA基因高表达及干扰载体的构建及其在结肠癌研究中的初步应用
Bingping Wang,Jinkai Duan,Jie Zhou et al.
Bingping Wang et al.
Background: The functional characterization of Epithelial Cell Adhesion Molecule (EpCAM) in colorectal cancer (CRC) progression has been constrained by methodological limitations, particularly the potential for truncated ...
A long journey towards genome editing technologies in plants: a technical and critical review of genome editing technologies [0.03%]
植物基因组编辑技术的漫长之旅——基因组编辑技术的技术及批判性评论
Dylan Gallo,Anne-Cécile Meunier,Christophe Périn
Dylan Gallo
Advancements in genome editing technologies, notably CRISPR/Cas9, base editing (BE), and prime editing (PE), have revolutionized plant biotechnology, offering unprecedented precision in crop improvement to address the ongoing global warming...
Correction: Rewriting the script: gene therapy and genome editing for von Willebrand Disease [0.03%]
纠正：重写剧本：血管性血友病的基因治疗和基因编辑
Alastair Barraclough,Isabel Bär,Tirsa van Duijl et al.
Alastair Barraclough et al.
[This corrects the article DOI: 10.3389/fgeed.2025.1620438.]. Keywords: CRISPR-Cas; VWD; delivery; endotheli...
Published Erratum
Frontiers in genome editing. 2025 Nov 7:7:1719330. DOI:10.3389/fgeed.2025.1719330 2025
Proceedings of the second annual meeting of GenE-HumDi (COST Action 21113) [0.03%]
GenE-HumDi欧洲成本行动20113第二年会会议纪要
María Ortiz-Bueno,Iris Ramos-Hernández,Luis Algeciras-Jiménez et al.
María Ortiz-Bueno et al.
Genome editing for the treatment of human disease (GenE-HumDi) is an EU-funded COST Action for the development and consolidation of academic, industrial and healthcare feedback networks aiming to accelerate, foster and harmonize the approva...
Genome editing approaches to harness cytokinin-salicylic acid crosstalk for plant protection [0.03%]
利用细胞分裂素-水杨酸互作的植物保护基因编辑策略
Muhammad Naseem,Khalid Muhammad
Muhammad Naseem
Editorial: Genome editing for climate change adaptation in agriculture: innovations, applications, and regulatory considerations [0.03%]
编辑室：用于农业气候适应性管理的基因组编辑：创新、应用与监管问题
Koppolu Raja Rajesh Kumar,Prashant Kumar Singh
Koppolu Raja Rajesh Kumar
CRISPR/Cas9- and Cas3-mediated modification of copy number variation in rice [0.03%]
用于水稻拷贝数变异的CRISPR/Cas9和Cas3介导的方法
Hyungjun Park,Takeshi Kuroha,Hiroaki Saika et al.
Hyungjun Park et al.
Introduction: Copy number variation (CNV) is one of the crucial elements among genomic structural variations that span plant breeding. However, its impact on agricultural traits has remained elusive. ...
From GWAS signal to function: targeted CRISPR activation enables functional characterization of non-coding SNPs in chickens [0.03%]
从GWAS信号到功能：靶向CRISPR激活使鸡非编码SNP的功能表征成为可能
Jaewon Kim,Jeong Hoon Han,Minjun Kim et al.
Jaewon Kim et al.
Genome-wide association studies (GWAS) have identified numerous single nucleotide polymorphisms (SNPs) associated with complex traits in poultry. However, most GWAS-identified variants reside in non-coding regions, making their functional r...
CRISPR-mediated generation of a tumor-associated antigen-deficient Raji platform to investigate antigen loss in CAR-T cell therapy [0.03%]
基于CRISPR技术构建新型Raji细胞平台用于研究CAR-T治疗中肿瘤抗原丢失机制
Aditya Ramdas Iyer,Mehwish Nafiz,Pragya Gupta et al.
Aditya Ramdas Iyer et al.
Tumor-associated antigen (TAA) loss remains a significant mechanism of resistance to chimeric antigen receptor (CAR) T cell therapy, leading to relapse in patients with B-cell malignancies and representing a major clinical challenge. Recent...
Consumer choices regarding genome-edited food crops: lessons from Japan [0.03%]
关于基因组编辑作物的消费者选择：来自日本的经验教训
Tetsuya Ishii
Tetsuya Ishii
Japan has rapidly deregulated certain types of agricultural genome editing, yet the societal integration of these products warrants further investigation. This paper analyzed the sale and people's perception of genome-edited food crops in J...