Ultradeformable liposomal delivery of vismodegib modulates its biological activity in melanoma cells [0.03%]
超可变形脂质体递送vorinostat调节其在黑色素瘤细胞中的生物活性
Maria Natalia Calienni,Cristian Sandoval-Acuña,Petra Potomová et al.
Maria Natalia Calienni et al.
Introduction: Vismodegib (VDG), a Smoothened inhibitor approved for basal cell carcinoma, has potential for repurposing in other tumors in which Hedgehog (Hh) signaling contributes to malignancy. However, systemic VDG tre...
Development of remote radar based vital sign acquisition for emergency department patient triage [0.03%]
基于远程雷达的生命体征获取在急诊科分级中的应用开发
Yossi Shaya,Gil Levy,Akiva Esterson et al.
Yossi Shaya et al.
Introduction: To enable remote acquisition of patients' vital signs, ELTA Systems Ltd. developed a Radar remote vital signs acquisition system (TAMAR). The system identifies chest and neck respiratiory movements and pulse...
Hospital efficiency assessment: a systematic review of DEA and hybrid DEA-machine learning approaches [0.03%]
基于DEA和混合DEA-机器学习方法的医院效率评价系统性研究
Nesrin Alkan,Ubeyde Kaan Koluk,Bilal Baris Alkan et al.
Nesrin Alkan et al.
The increasing complexity of healthcare systems and growing resource constraints have made hospital efficiency assessment central to healthcare management and policy. Data Envelopment Analysis (DEA) has been widely used to evaluate hospital...
A stacked cavity-backed metamaterial antenna for confined hyperthermia of subcutaneous fat in ISM band [0.03%]
一种用于ISM波段皮下脂肪局域化热疗的多层空腔耦合超材料天线
Dong-Min Lee,Yun-Jae Jung,Ikhwan Kim et al.
Dong-Min Lee et al.
Introduction: Hyperthermia has emerged as a versatile modality in oncology, rehabilitation, and aesthetic medicine, yet conventional RF devices often suffer from insufficient penetration and collateral epidermal heating. ...
Case Report: Listeria monocytogenes meningitis complicated by an acute exacerbation of chronic obstructive pulmonary disease: the key diagnostic role of metagenomic high-throughput sequencing [0.03%]
病例报告：李斯特菌引起的脑膜炎合并慢性阻塞性肺病急性加重：宏基因组高通量测序在关键诊断中的作用
Yiwei Chen,Dacheng Tian,Yixuan Bai et al.
Yiwei Chen et al.
Background: Listeria monocytogenes is an opportunistic foodborne pathogen that causes severe invasive infections, such as meningitis, primarily in immunocompromised individuals, the elderly, and pregnant women. Diagnosis ...
China's regulatory regime for medical biotechnology: evolution, challenges, and future perspectives [0.03%]
中国医药生物技术监管体系的演进、挑战与未来展望
Enkai Zhang
Enkai Zhang
Modern medical biotechnology, while reshaping human healthcare and enhancing social welfare, may also pose biological risks. During the past 40 years, China has made considerable strides in becoming a global leader in biotechnology, necessi...
Gold nanoparticles in skin drug delivery: a bibliometric analysis of research trends from 2015 to 2025 [0.03%]
皮肤药物输送中金纳米颗粒的研究趋势（2015-2025年）文献计量分析
Mohammed Arif,Karim Mousa,Haider Butt
Mohammed Arif
Gold nanoparticles (AuNPs) have emerged as highly effective nanocarriers for skin drug delivery due to their tunable physicochemical properties, large surface area, and ease of functionalization. Over the past decade, research in this field...
Public trust in AI-enabled telemedicine: affective, cognitive, and structural dimensions insights from multi-platform big data analytics [0.03%]
基于多平台大数据分析的AI赋能型远程医疗公共信任情感、认知和结构维度启示
Faisal Binsar,Mohammad Hamsal,Erwin Tenggono et al.
Faisal Binsar et al.
Artificial intelligence (AI) is transforming healthcare delivery, with telemedicine emerging as one of its most viable and socially impactful applications, raising important questions about how public trust is formed and sustained in AI-ena...
Attention-guided and MIL-constrained CycleGAN for high-fidelity virtual p16 and Ki-67 staining [0.03%]
一种注意引导和MIL约束的CycleGAN用于虚拟p16和Ki-67染色_HIGH_fidility虚拟p16和ki-67染色的Attention-guided and MIL-constrained CycleGAN方法研究
Xinli Lei,Yuefeng Xie,Andi Duan et al.
Xinli Lei et al.
Cervical intraepithelial neoplasia (CIN) grading relies on both morphological assessment from hematoxylin and eosin (H&E) slides and biomarker expression from immunohistochemistry (IHC), such as p16 and Ki-67. However, conventional IHC stai...
Mamba-ADR: adverse drug reaction detection from social-media using state-space regression model [0.03%]
基于状态空间回归模型的社交媒体药物不良反应检测方法(Mamba-ADR)
Shanwen Zhang,Ting Zhang,Yahong Ma
Shanwen Zhang
Drug adverse reactions (ADRs) is vital to minimize health risks and reduce drug development costs. Extracting ADRs (ADRE) from social media is a vital supplement to conventional pharmacovigilance databases. However, it remains particularly ...